Jatrophalactam, a novel diterpenoid lactam isolated from Jatropha curcas

Organic Letters

Volumn 11, Issue 23, 2009, Pages 5522-5524

  Wang, Xia Chang ^a   Zheng, Zong Ping ^a   Gan, Xian Wen ^a   Hu, Li Hong ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

[No Author keywords available]

Indexed keywords

DITERPENE; LACTAM;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; DRUG SCREENING; HUMAN; ISOLATION AND PURIFICATION; JATROPHA; NUCLEAR MAGNETIC RESONANCE; PLANT ROOT; X RAY CRYSTALLOGRAPHY;

CRYSTALLOGRAPHY, X-RAY; DITERPENES; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; JATROPHA; LACTAMS; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PLANT ROOTS;

EID: 72449167881     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol902349f     Document Type: Article

References (9)

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8. 3, 331.2147)
9. 3, crystal dimensions 0.02 × 0.07 × 0.10 mm was used for measurement on a Bruker APEX SMART-CCD diffractometer with a graphite monochromater. The total number of reflections measured was 48.13, of which 3157 were observed, T > 2σ(T). Final indices: R = 0.0702, wR2 = 0. 1990. The crystal structure of 1 was solved by direct method SHLXS-97 (Sheldrick, 1990) and expanded using difference Fourier technique, refined by the program SHLXL-97 (Sheldrick, 1997) and the full-matrix least-squares calculations. Crystallographic data for compound 1 have been deposited with the Cambridge Crystallographic Data Centre (deposition number CCDC 7435.16). Copies of the data can be obtained, free of charge, on application to the director, CCDC 12 Union Road, Cambridge CB2 1EZ, UK (fax: +44 1223 336033 or email: deposit@ccdc.cam.ac.uk).