Indole-diterpenes and ergot alkaloids in Cynodon dactylon (Bermuda grass) infected with Claviceps cynodontis from an outbreak of tremors in cattle

Journal of Agricultural and Food Chemistry

Volumn 57, Issue 23, 2009, Pages 11112-11119

  Uhlig, Silvio ^a   Botha, Christo J ^b   Vrålstad, Trude ^a   Rolén, Elin ^a   Miles, Christopher O ^a  

^a NORWEGIAN VETERINARY INSTITUTE   (Norway)

^b UNIVERSITY OF PRETORIA   (South Africa)

Author keywords

C. paspali; Claviceps; Cynodon; Mycotoxin; Paspalitrem; Staggers; Tremorgen

Indexed keywords

DITERPENE; ERGOT ALKALOID; INDOLE; INDOLE DERIVATIVE; MYCOTOXIN;

ANIMAL; ANIMAL DISEASE; ANIMAL FOOD; ARTICLE; CATTLE; CATTLE DISEASE; CHEMISTRY; CYNODON; EPIDEMIC; GENETICS; HYPOCREALES; ISOLATION AND PURIFICATION; METABOLISM; MICROBIOLOGY; PLANT DISEASE; TREMOR;

ANIMAL FEED; ANIMALS; CATTLE; CATTLE DISEASES; CYNODON; DISEASE OUTBREAKS; DITERPENES; ERGOT ALKALOIDS; HYPOCREALES; INDOLES; MYCOTOXINS; PLANT DISEASES; TREMOR;

BOS; CLAVICEPS; CLAVICEPS CYNODONTIS; CLAVICEPS PASPALI; CYNODON DACTYLON; MAMMALIA;

EID: 72449149208     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf902208w     Document Type: Article

References (23)

1. Saikia, S.; Nicholson, M. J.; Young, C.; Parker, E. J.; Scott, B. The genetic basis for indole - diterpene chemical diversity in filamentous fungi. Mycol. Res. 2008, 112, 184-199.
2. Křen, V.; Cvak, L. Ergot - The Genus Claviceps; Harwood Academic Publishers: Amsterdam, The Netherlands, 1999.
3. (3) Botha, C. J.; Kellerman, T. S.; Fourie, N. A tremorgenic mycotoxicosis in cattle caused by Paspalum distichum (L.) infected by Claviceps paspali. J. S. Afr. Vet. Assoc. 1996, 67, 36-37. (Pubitemid 126443897)
4. Muthusubramanian, V.; Bandyopadhyay, R.; Reddy, D. R.; Tooley, P. W. Cultural characteristics, morphology, and variation within Claviceps africana and C. sorghi from India. Mycol. Res. 2006, 110, 452-464.
5. (5) Saikia, S.; Parker, E. J.; Koulman, A.; Scott, B. Four gene products are required for the fungal synthesis of the indole-diterpene, paspaline. FEBS Lett. 2006, 580, 1625-1630. (Pubitemid 43290362)
6. + channels. J. Pharmacol, Exp. Ther. 2008, 327, 657-664.
7. Knaus, H. G.; McManus, O. B.; Lee, S. H.; Schmalhofer, W. A.; Garcia-Calvo, M.; Helms, L. M.; Sanchez, M.; Giangiacomo, K.; Reuben, J. P.; Smith, A. B. III. Tremorgenic indole alkaloids potently inhibit smooth muscle high-conductance calcium-activated potassium channels. Biochemistry 1994, 33, 5819-5828.
8. Cole, R. J.; Dorner, J. W.; Lansden, J. A.; Cox, R. H.; Pape, C.; Cunfer, B.; Nicholson, S. S.; Bedell, D. M. Paspalum staggers: isolation and identification of tremorgenic metabolites from sclerotia of Claviceps pospali. J. Agric. Food Chem. 1977, 25, 1197-1201.
9. Kellerman, T. S.; Coetzer, J. A. W.; Naude, T. W.; Botha, C. J. Plant Poisoning and Mycotoxkoses in Livestock in Southern Africa; Oxford University Press: Cape Town, South Africa, 2005.
10. Porter, J. K.; Bacon, C. W.; Robbins, J. D. Major alkaloids of a Claviceps isolated from toxic Bermuda grass. J. Agric. Food Chem. 1974, 22, 838-841.
11. Langdon, R. F. New species of Claviceps. Univ. Queensl. Pap., Dep. Bot. 1954, 3, 37-40.
12. Conway, K. E.; Shelby, R. A. First report on formation of sclerotia of Claviceps purpurea on Bermuda grass (Cynodon dactylon). Plant Dis. 1992, 76, 1077.
13. Gardes, M.; Bruns, T. D. ITS primers with, enhanced specificity for basidiomycetes -application to the identification of mycorrhizae and rust. Mol. Ecol. 1993, 2, 113-118.
14. Vrålstad, T.; Knutsen, A. K.; Tengs, T.; Hoist-Jensen, A. A quantitative TaqMan MGB real-time polymerase chain reaction based assay for detection of the causative agent of crayfish plague Aphanomyces astaci. Vet. Microbiol. 2009, 137, 146-155.
15. Hall, T. A. BioEdit: a user friendly biological sequence alignment editor and analysis program for Windows 95/98/NT. Nucleic Acids Symp. Ser. 1999, 41, 95-98.
16. Kibbe, W. A. OligoCalc: an online oligonucleotide properties calculator, Nucleic Acids Res. 2007, 35 (Suppl. 2), W43-W46.
17. Altschul, S. F.; Madden, T. L.; Schaffer, A. A.; Zhang, J. H.; Zhang, Z.; Miller, W.; Lipman, D. J. Gapped BLAST and PSI-BLAST: a new generation, of protein database search programs. Nucleic Acids Res. 1997, 25, 3389-3402.
18. Cole, R. J.; Jarvis, B. B.; Schweikert, M. A. Secondary Fungal Metabolites; Academic Press: San Diego, CA, 2003; Vol.I.
19. Pažoutová, S.; Parbery, D. P. The taxonomy and phytogeny of Claviceps. In Ergot - The Genus Claviceps; Křen, V.; Cvak, L. Eds.; Harwood Academic Publishers: Amsterdam, The Netherlands, 1999; pp 57-77.
20. Pažoutová, S. The phytogeny and evolution, of the genus Claviceps. Mycol. Res. 2001, 105, 275-283.
21. (21) Pažoutová, S.; Olšovská, J.; Šulc, M.; Chudíčková, M.; Flieger, M. Claviceps nigricans and Claviceps grohii: their alkaloids and phylogenetic placement, J. Nlat. Prod. 2008, 71, 1085-1088. (Pubitemid 352008914)
22. Pažoutová, S.; Odvody, G.; Frederickson, D. E. Ergot fungus Claviceps cynodontis found on Bermuda grass (Cynodon dactylon) in the Americas. Can. J. Plant Pathol. 2005, 27, 541-546.
23. (23) Young, C. A.; Felitti, S.; Shields, K.; Spangenberg, G.; Johnson, R. D.; Bryan, G. T.; Saikia, S.; Scott, B. A complex gene cluster for indole-diterpene biosynthesis in the grass endophyte Neotyphodium lolii. Fungal Gen. Biol. 2006, 43, 679-693. (Pubitemid 44292548)