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1
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7244256407
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SuperGen Submits Application for EMEA Approval of Orathecin™
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SuperGen Inc. Media Release: 1 Jul Available from URL
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SuperGen Inc. SuperGen Submits Application for EMEA Approval of Orathecin™. Media Release: 1 Jul 2004. Available from URL: http://www.supergen.com
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(2004)
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2
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7244262285
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SuperGen's Orathecin (rubitecan) capsules granted 'orphan product' status in Europe
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SuperGen Inc. Media Release: 11 Jun Available from URL
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SuperGen Inc. SuperGen's Orathecin (rubitecan) capsules granted 'orphan product' status in Europe. Media Release: 11 Jun 2003. Available from URL: http://www.supergen.com
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(2003)
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3
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7244250579
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SuperGen Reports Results of Phase III Study of Orathecin™ In Patients With Advanced Pancreatic Cancer
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SuperGen Inc. Media Release: 30 May Available from: URL
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SuperGen Inc. SuperGen Reports Results of Phase III Study of Orathecin™ In Patients With Advanced Pancreatic Cancer. Media Release: 30 May 2003. Available from: URL: http://www.supergen.com
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(2003)
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4
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7244247640
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SuperGen Announces Additional Data from (Phase III Study of Orathecin™ in Patients With Advanced Pancreatic Cancer
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SuperGen Inc. Media Release: 2 Jun Available from URL
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SuperGen Inc. SuperGen Announces Additional Data from (Phase III Study of Orathecin™ in Patients With Advanced Pancreatic Cancer. Media Release: 2 Jun 2003. Available from URL: http:/ /www.supergen.com
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(2003)
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5
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7244253461
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SuperGen Receives Patent Notices of Allowance for Rubitecan-Related Claims
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SuperGen Inc. Media Release: 16 Jul Available from URL http://www.supergen.com
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SuperGen Inc. SuperGen Receives Patent Notices of Allowance for Rubitecan-Related Claims. Media Release: 16 Jul 2003. Available from URL: http://www.supergen.com
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(2003)
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6
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0031909978
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A phase I clinical and pharmacological study of oral 9-nitrocamptothecin, a novel water-insoluble topoisomerase I inhibitor
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Jan
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Verschraegen CF, Natelson EA, Giovanella BC, et al. A phase I clinical and pharmacological study of oral 9-nitrocamptothecin, a novel water-insoluble topoisomerase I inhibitor. Anti-Cancer Drugs 9: 36-44, Jan 1998
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(1998)
Anti-Cancer Drugs
, vol.9
, pp. 36-44
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Verschraegen, C.F.1
Natelson, E.A.2
Giovanella, B.C.3
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7
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7244228395
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Pharmacology study of multiple oral doses of 9-nitro-camptothecin
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Verschraegen CF, Harris N, Steger M. Pharmacology study of multiple oral doses of 9-nitro-camptothecin. Annals of Oncology 9 (Suppl. 2): 70, 1998
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(1998)
Annals of Oncology
, vol.9
, Issue.SUPPL. 2
, pp. 70
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Verschraegen, C.F.1
Harris, N.2
Steger, M.3
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8
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0033110137
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A phase II clinical and pharmacological study of oral 9-nitrocamptothecin in patients with refractory epithelial ovarian, tubal or peritoneal cancer
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Apr
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Verschraegen CF, Gupta E, Loyer E. A phase II clinical and pharmacological study of oral 9-nitrocamptothecin in patients with refractory epithelial ovarian, tubal or peritoneal cancer. Anti-Cancer Drugs 10: 375-383, Apr 1999
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(1999)
Anti-Cancer Drugs
, vol.10
, pp. 375-383
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Verschraegen, C.F.1
Gupta, E.2
Loyer, E.3
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9
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0006677085
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Effect of food intake on the pharmacokinetics of a single administration of oral Rubitecan (RFS-2000), a topoisomerase-I-inhibiting camptothecin analogue
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11th NCI-EORTC-AACR symposium on new drugs in cancer therapy: (plus poster), 7 Nov
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Schöffski P, Herr A, Beijnen J, et al. Effect of food intake on the pharmacokinetics of a single administration of oral Rubitecan (RFS-2000), a topoisomerase-I-inhibiting camptothecin analogue. 11th NCI-EORTC-AACR symposium on new drugs in cancer therapy: 91 (plus poster), 7 Nov 2000
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(2000)
, pp. 91
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Schöffski, P.1
Herr, A.2
Beijnen, J.3
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10
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7244226787
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Effect of food intake on the pharmacokinetics of the oral camptothecin analogue rubitecan: Phase II- and pharmacologic evaluation in non-pretreated patients with metastatic colorectal cancer
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Sep
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Schöffski P, Herr A, van den Brande J, et al. Effect of food intake on the pharmacokinetics of the oral camptothecin analogue rubitecan: phase II- and pharmacologic evaluation in non-pretreated patients with metastatic colorectal cancer. Onkologie 24 (Suppl. 6): 4, Sep 2001
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(2001)
Onkologie
, vol.24
, Issue.SUPPL. 6
, pp. 4
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Schöffski, P.1
Herr, A.2
van den Brande, J.3
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11
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7244226788
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SuperGen's RFS 2000 shows 63% response or stable disease in pancreatic cancer patients. Longest survival data - 16.2 months - Ever reported for pancreatic cancer patients
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SuperGen. Media Release [2 pages], 27 May
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SuperGen. SuperGen's RFS 2000 shows 63% response or stable disease in pancreatic cancer patients. Longest survival data - 16.2 months - ever reported for pancreatic cancer patients. Media Release [2 pages], 27 May 1998
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(1998)
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12
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7244244394
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M.D. Anderson study concludes SuperGen's rubitecan is active in chronic myelomonocytic leukemia (CM-ML) and myelodysplastic syndromes (MDS)
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SuperGen Inc. Media Release [2 pages], 11 Dec Available from URL
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SuperGen Inc. M.D. Anderson study concludes SuperGen's rubitecan is active in chronic myelomonocytic leukemia (CM-ML) and myelodysplastic syndromes (MDS). Media Release [2 pages], 11 Dec 2001. Available from URL: http://www.supergen.com
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(2001)
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14
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0036185945
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Phase II trial of 9-nitrocamptothecin (RFS 2000) for patients with metastatic cutaneous or uveal melanoma
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Feb
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Ellerhorst JA, Bedikian AY, Smith TM, et al. Phase II trial of 9-nitrocamptothecin (RFS 2000) for patients with metastatic cutaneous or uveal melanoma. Anti-Cancer Drugs 13: 169-172, Feb 2002
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(2002)
Anti-Cancer Drugs
, vol.13
, pp. 169-172
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Ellerhorst, J.A.1
Bedikian, A.Y.2
Smith, T.M.3
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15
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0037216220
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A phase I study of 9-nitrocamptothecin given concurrently with capecitabine in patients with refractory, metastatic solid tumors
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1 Jan
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Michaelson MD, Ryan DP, Fuchs CS, et al. A phase I study of 9-nitrocamptothecin given concurrently with capecitabine in patients with refractory, metastatic solid tumors. Cancer 97: 148-154, 1 Jan 2003
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(2003)
Cancer
, vol.97
, pp. 148-154
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Michaelson, M.D.1
Ryan, D.P.2
Fuchs, C.S.3
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16
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0027399619
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9-Nitro-camptothecin delays growth of U-937 leukemia tumors in nude mice and is cytotoxic or cytostatic for human myelomonocytic leukemia lines in vitro
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Feb
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Pantazis P, Mendoza JT, Early JA, et al. 9-Nitro-camptothecin delays growth of U-937 leukemia tumors in nude mice and is cytotoxic or cytostatic for human myelomonocytic leukemia lines in vitro. European Journal of Haematology 50: 81-89, Feb 1993
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(1993)
European Journal of Haematology
, vol.50
, pp. 81-89
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Pantazis, P.1
Mendoza, J.T.2
Early, J.A.3
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17
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0027467836
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Regression of human breast carcinoma tumors in immunodeficient mice treated with 9-nitrocamptothecin: Differential response of nontumorigenic and tumorigenic human breast cells in vitro
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1 Apr
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Pantazis P, Early JA, Kozielski AJ, et al. Regression of human breast carcinoma tumors in immunodeficient mice treated with 9-nitrocamptothecin: differential response of nontumorigenic and tumorigenic human breast cells in vitro. Cancer Research 53: 1577-1582, 1 Apr 1993
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(1993)
Cancer Research
, vol.53
, pp. 1577-1582
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Pantazis, P.1
Early, J.A.2
Kozielski, A.J.3
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18
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0031963961
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9-Nitrocamptothecin inhibits tumor necrosis factor-mediated activation of human immunodeficiency virus type 1 and enhances apoptosis in a latently infected T cell clone
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1 Jan
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Moulton S, Pantazis P, Epstein JS, et al. 9-Nitrocamptothecin inhibits tumor necrosis factor-mediated activation of human immunodeficiency virus type 1 and enhances apoptosis in a latently infected T cell clone. AIDS Research and Human Retroviruses 14: 39-49, 1 Jan 1998
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(1998)
AIDS Research and Human Retroviruses
, vol.14
, pp. 39-49
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Moulton, S.1
Pantazis, P.2
Epstein, J.S.3
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19
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0034967284
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9-Nitrocamptothecin inhibits HIV-1 replications in human peripheral blood lymphocytes: A potential alternative for HIV-infection/AIDS therapy
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No
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Hung C-L, Doniger J, Palini A, et al. 9-Nitrocamptothecin inhibits HIV-1 replications in human peripheral blood lymphocytes: a potential alternative for HIV-infection/AIDS therapy. Journal of Medical Virology 64: 238-244, No. 3, 2001
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(2001)
Journal of Medical Virology
, vol.64
, Issue.3
, pp. 238-244
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Hung, C.-L.1
Doniger, J.2
Palini, A.3
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20
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7244220430
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Study shows SuperGen's rubitecan has significant activity in several hematological malignancies
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SuperGen Inc. Media Release [2 pages], 15 Sep Available from URL
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SuperGen Inc. Study shows SuperGen's rubitecan has significant activity in several hematological malignancies. Media Release [2 pages], 15 Sep 2000. Available from URL: http://www.supergen.com
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(2000)
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21
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7244259370
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Independent Review of Orathecin™ Phase III Trial Supports Drug's Activity in Pancreatic Cancer Patients who Failed Prior Treatments
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SuperGen Inc. Media Release: 17 Nov Available from URL
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SuperGen Inc. Independent Review of Orathecin™ Phase III Trial Supports Drug's Activity in Pancreatic Cancer Patients who Failed Prior Treatments. Media Release: 17 Nov 2003. Available from URL: http://www.supergen.com
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(2003)
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