Adaptations to free-fall impact are different in the shafts and bone ends of rat forelimbs

Journal of Applied Physiology

Volumn 97, Issue 5, 2004, Pages 1859-1865

  Welch, J M ^a   Weaver, C M ^a   Turner, C H ^b  

^a PURDUE UNIVERSITY   (United States)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Bone strength; Exercise; Ground reaction force; Peripheral quantitative computed tomography; Rats

Indexed keywords

ADAPTATION; ANIMAL EXPERIMENT; ARTICLE; BIOMECHANICS; BONE DENSITY; BONE GROWTH; BONE MINERAL; BONE STRENGTH; COMPRESSIVE STRENGTH; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; FALLING; FEMALE; FOREFOOT; FORELIMB; GEOMETRY; LEG; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; TIBIA; TIBIA SHAFT; TRABECULAR BONE; VOLUMETRY; WEIGHT BEARING;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; BONE AND BONES; BONE DENSITY; COMPRESSIVE STRENGTH; DIAPHYSES; FEMALE; FORELIMB; FRACTURES, BONE; HINDLIMB; RATS; RATS, INBRED F344; TOMOGRAPHY, X-RAY COMPUTED; ULNA;

EID: 7244244130     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/japplphysiol.00438.2004     Document Type: Article

References (39)

1. Arts CJ, Govers CA, van den Berg H, and Thijssen JH. Effects of wheat bran and energy restriction on onset of puberty, cell proliferation and development of mammary tissue in female rats. Acta Endocrinol 126: 451-459, 1992.
2. Bain LJ and Engelhardt M. Introduction to Probability and Mathematical Statistics: N. Scituate, MA: Duxbury, 2000.
3. Bass SL, Saxon L, Daly RM, Turner CH, Robling AG, Seeman E, and Stuckey S. The effect of mechanical loading on the size and shape of bone in pre-, peri-, and postpubertal girls: a study in tennis players. J Bone Miner Res 17: 2274-2280, 2002.
4. Bennell K, Crossley K, Jayarajan J, Walton E, Warden S, Kiss ZS, and Wrigley T. Ground reaction forces and bone parameters in females with tibial stress fracture. Med Sci Sports Exerc 36: 397-404, 2004.
5. Bourrin S, Palle S, Pupier R, Vico L, and Alexandre C. Effect of physical training on bone adaptation in three zones of the rat tibia. J Bone Miner Res 10: 1745-1752, 1995.
6. Fuchs RK, Bauer JJ, and Snow CM. Jumping improves hip and lumbar spine bone mass in prepubescent children: a randomized controlled trial. J Bone Miner Res 16: 148-156, 2001.
7. Gross TS, Poliachik SL, Ausk BJ, Sandford DA, Becker BA, and Srinivasan S. Why rest stimulates bone formation: a hypothesis based on complex adaptive phenomenon. Exerc Sport Sci Rev 32: 9-13, 2004.
8. Heinonen A, Sievänen H, Kyröläinen H, Perttunen J, and Kannus P. Mineral mass, size, and estimated mechanical strength of triple jumpers' lower limb. Bone 29: 279-285, 2001.
9. Hernandez CJ, Beaupre GS, and Carter DR. A theoretical analysis of the relative influences of peak BMD, age-related bone loss and menopause on the development of osteoporosis. Osteoporos Int 14: 843-847, 2003.
10. Hockly E, Cordery PM, Woodman B, Mahal A, van Dellen A, Blakemore C, Lewis CM, Hannan AJ, and Bates GP. Environmental enrichment slows disease progression in R6/2 Huntington's disease mice. Ann Neurol 51: 235-242, 2002.
11. Honda A, Umemura Y, and Nagasawa S. Effect of high-impact and low-repetition training on bones in ovariectomized rats. J Bone Miner Res 16: 1688-1693, 2001.
12. Hsieh YF and Silva MJ. In vivo fatigue loading of the rat ulna induces both bone formation and resorption and leads to time-related changes in bone mechanical properties and density. J Orthop Res 20: 764-771, 2002.
13. Huang TH, Lin SC, Chang FL, Hsieh SS, Liu SH, and Yang RS. Effects of different exercise modes on mineralization, structure, and biomechanical properties of growing bone. J Appl Physiol 95: 300-307, 2003.
14. Huang TH, Yang RS, Hsieh SS, and Liu SH. Effects of caffeine and exercise on the development of bone: a densitometric and histomorphometric study in young Wistar rats. Bone 30: 293-299, 2002.
15. Järvinen TL, Kannus P, and Sievänen H. Have the DXA-based exercise studies seriously underestimated the effects of mechanical loading on bone? J Bone Miner Res 14: 1634-1635, 1999.
16. Karlsson MK, Johnell O, and Obrant KJ. Is bone mineral density advantage maintained long-term in previous weight lifters? Calcif Tissue Int 57: 325-328, 1995.
17. Kodama Y, Umemura Y, Nagasawa S, Beamer WG, Donahue LR, Rosen CJ, Bavlink DJ, and Farley JR. Exercise and mechanical loading increase periosteal bone formation and whole bone strength in C57BL/6J mice but not in C3H/Hej mice. Calcif Tissue Int 66: 298-306, 2000.
18. Kontulainen S, Kannus P, Haapasalo H, Sievänen H, Pasanen M, Heinonen A, Oja P, and Vuori I. Good maintenance of exercise-induced bone gain with decreased training of female tennis and squash players: a prospective 5-year follow-up study of young and old starters and controls. J Bone Miner Res 16: 195-201, 2001.
19. Kontulainen S, Sievänen H, Kannus P, Pasanen M, and Vuori I. Effect of long-term impact-loading on mass, size, and estimated strength of humerus and radius of female racquet-sports players: a peripheral quantitative computed tomography study between young and old starters and controls. J Bone Miner Res 17: 2281-2289, 2002.
20. Kotha SP, Hsieh YF, Strigel RM, Müller R, and Silva MJ. Experimental and finite element analysis of the rat ulnar loading model - correlations between strain and bone formation following fatigue loading. J Biomech 37: 541-548, 2004.
21. Liu L, Maruno R, Mashimo T, Sanka K, Higuchi T, Hayashi K, Shirasaki Y, Mukai N, Saitoh S, and Tokuyama K. Effects of physical training on cortical bone at midtibia assessed by peripheral QCT. J Appl Physiol 95: 219-224, 2003.
22. Nagasawa S and Umemura Y. Bone hypertrophy in rats: effects of jump number and height. Adv Exerc Sports Physiol 8: 87-92, 2002.
23. Nurmi-Lawton JA, Baxter-Jones AD, Mirwald RL, Bishop JA, Taylor P, Cooper C, and New SA. Evidence of sustained skeletal benefits from impact-loading exercise in young females: a 3-year longitudinal study. J Bone Miner Res 19: 314-322, 2004.
24. Pajamaki I, Kannus P, Vuohelainen T, Sievänen H, Tuukkanen J, Järvinen M, and Järvinen TL. The bone gain induced by exercise in puberty is not preserved through a virtually life-long deconditioning: a randomized controlled experimental study in male rats. J Bone Miner Res 18: 544-552, 2003.
25. Robling AG, Hinant FM, Burr DB, and Turner CH. Improved bone structure and strength after long-term mechanical loading is greatest if loading is separated into short bouts. J Bone Miner Res 17: 1545-1554, 2002.
26. Robling AG, Hinant FM, Burr DB, and Turner CH. Shorter, more frequent mechanical loading sessions enhance bone mass. Med Sci Sports Exerc 34: 196-202, 2002.
27. Seeman E. Invited Review: Pathogenesis of osteoporosis. J Appl Physiol 95: 2142-2151, 2003.
28. Sievänen H, Uusi-Rasi K, Heinonen A, Oja P, and IV. Disproportionate, age-related bone loss in long bone ends: a structural analysis based on dual-energy X-ray absorptiometry. Osteoporos Int 10: 295-302, 1999.
29. Singh R, Umemura Y, Honda A, and Nagasawa S. Maintenance of bone mass and mechanical properties after short-term cessation of high impact exercise in rats. Int J Sports Med 23: 77-81, 2002.
30. Turner CH and Burr DB. Basic biomechanical measurements of bone: a tutorial. Bone 14: 595-608, 1993.
31. Turner CH, Forwood MR, Rho JY, and Yoshikawa T. Mechanical loading thresholds for lamellar and woven bone formation. J Bone Miner Res 9: 87-97, 1994.
32. Turner CH, Woltman TA, and Belongia DA. Structural changes in rat bone subjected to long-term, in vivo mechanical loading. Bone 13: 417-422, 1992.
33. Umemura Y, Baylink DJ, Wergedal JE, Mohan S, and Srivastava AK. A time course of bone response to jump exercise in C57BL/6J mice. J Bone Miner Metab 20: 209-215, 2002.
34. Umemura Y, Ishiko T, Tsujimoto H, Miura H, Mokushi N, and Suzuki H. Effects of jump training on bone hypertrophy in young and old rats. Int J Sports Med 16: 364-367, 1995.
35. Umemura Y, Ishiko T, Yamauchi T, Kurono M, and Mashiko S. Five jumps per day increase bone mass and breaking force in rats. J Bone Miner Res 12: 1480-1485, 1997.
36. Umemura Y, Sogo N, and Honda A. Effects of intervals between jumps or bouts on osteogenic response to loading. J Appl Physiol 93: 1345-1348, 2002.
37. Yen JK, Aloia JF, and Yasumura S. Effect of physical activity on calcium and phosphorus metabolism in the rat. Am J Physiol Endocrinol Metab 256: E1-E6, 1989.
38. Zanker CL, Osborne C, Cooke CB, Oldroyd B, and Truscott JG. Bone density, body composition and menstrual history of sedentary female former gymnasts, aged 20-32 years. Osteoporos Int 15: 145-154, 2004.
39. Zittermann A, Sabatschus O, Jantzen S, Platen P, Danz A, and Stehle P. Evidence for an acute rise of intestinal calcium absorption in response to aerobic exercise. Eur J Nutr 41: 189-196, 2002.