Phosphonoformate: A minimal transition state analogue inhibitor of the fosfomycin resistance protein, FosA

Biochemistry

Volumn 43, Issue 43, 2004, Pages 13666-13673

  Rigsby, Rachel E ^a   Rife, Chris L ^a,c   Fillgrove, Kerry L ^a   Newcomer, Marcia E ^b   Armstrong, Richard N ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b LOUISIANA STATE UNIVERSITY   (United States)

^c STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTICS; BINDING ENERGY; BIOCHEMISTRY; CATALYSIS; MICROORGANISMS;

ANTIBACTERIAL ACTIVITY; OXIRANE RING; PHOSPHONOFORMATE; TRANSITION STATE;

PROTEINS;

ETHYLENE OXIDE; FOSA PROTEIN; FOSCARNET; FOSFOMYCIN; FOSFOMYCIN RESISTANCE PROTEIN; LEWIS ACID; MANGANESE; OXYGEN; PHOSPHATE; PROTEIN DERIVATIVE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENOME; BINDING AFFINITY; CATALYSIS; CATALYST; CORRELATION ANALYSIS; CROSS LINKING; DIFFUSION COEFFICIENT; GENETIC CODE; GEOMETRY; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; ISOMER; MOLECULAR BIOLOGY; PHASE TRANSITION; PLASMID; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; REACTION ANALYSIS; SEQUENCE HOMOLOGY;

BACTERIAL PROTEINS; BINDING SITES; CATALYSIS; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; DRUG RESISTANCE, BACTERIAL; FOSCARNET; FOSFOMYCIN; GLUTATHIONE TRANSFERASE; KINETICS; MANGANESE; PHOSPHONIC ACIDS; PSEUDOMONAS AERUGINOSA;

BACTERIA (MICROORGANISMS); NEGIBACTERIA; POSIBACTERIA; PSEUDOMONAS; PSEUDOMONAS AERUGINOSA;

EID: 7244237919     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi048767h     Document Type: Article

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