Indirect detection of protein-metal binding: Interaction of serum transferrin with In 3+ and Bi 3+

Journal of the American Society for Mass Spectrometry

Volumn 15, Issue 11, 2004, Pages 1658-1664

  Zhang, Mingxuan ^a   Gumerov, Dmitry R ^a   Kaltashov, Igor A ^a   Mason, Anne B ^b  

^a UNIVERSITY OF MASSACHUSETTS   (United States)

^b UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IRON SEQUESTRATION; PROTEIN-METAL BINDING;

CELLS; CONFORMATIONS; IONS; IRON; MONOMERS;

PROTEINS;

ANTIULCER AGENT; BISMUTH; INDIUM; LIGAND; METAL DERIVATIVE; TRANSFERRIN RECEPTOR;

ARTICLE; CIRCULAR DICHROISM; ELECTROSPRAY MASS SPECTROMETRY; GAS; MEASUREMENT; METAL BINDING; PROTEIN CONFORMATION; PROTEIN INTERACTION; PROTEIN STRUCTURE; SPECTROSCOPY; TRANSFERRIN BLOOD LEVEL; ULTRAVIOLET SPECTROSCOPY;

BISMUTH; HUMANS; INDIUM; PROTEIN BINDING; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TRANSFERRIN;

VERTEBRATA;

EID: 7244229728     PISSN: 10440305     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jasms.2004.08.009     Document Type: Article

References (31)

1. H. Sun, H. Li, P.J. Sadler Transferrin as a metal ion mediator Chem. Rev. 99 1999 2817 2842
2. H. Li, H. Sun, Z.M. Qian The role of the transferrin-transferrin-receptor system in drug delivery and targeting Trends Pharmacol. Sci. 23 2002 206 209
3. X. Yu, M. Wojciechowski, C. Fenselau Assessment of metals in reconstituted metallothioneins by electrospray mass spectrometry Anal. Chem. 65 1993 1355 1359
4. P. Hu, Q.Z. Ye, J.A. Loo Calcium stoichiometry determination for calcium binding proteins by electrospray ionization mass spectrometry Anal. Chem. 66 1994 4190 4194
5. D.R. Gumerov, I.A. Kaltashov Dynamics of iron release from transferrin N-lobe studied by electrospray ionization mass spectrometry Anal. Chem. 73 2001 2565 2570
6. D.R. Gumerov, A.B. Mason, I.A. Kaltashov Interlobe communication in human serum transferrin Metal binding and conformational dynamics investigated by electrospray ionization mass spectrometry Biochemistry 42 2003 5421 5428
7. C.J. Anderson, M.J. Welch Radiometal-labeled agents (nontechnetium) for diagnostic imaging Chem. Rev. 99 1999 2219 2234
8. G.G. Briand, N. Burford Bismuth compounds and preparations with biological or medicinal relevance Chem. Rev. 99 1999 2601 2658
9. 213Bi, and their decay chain related radionucleotides, for therapeutic applications Chem. Rev. 101 2001 2019 2036
10. W.R. Harris, L. Messori A comparative study of aluminum(III), gallium(III), indium(III), and thallium(III) binding to human serum transferrin Coord. Chem. Rev. 228 2002 237 262
11. H. Sun, K.Y. Szeto Binding of bismuth to serum proteins implication for targets of Bi(III) in blood plasma J. Inorg. Biochem. 94 2003 114 120
12. L.A. Tillman, F.M. Drake, J.S. Dixon, J.R. Wood Review article Safety of bismuth in the treatment of gastrointestinal diseases Aliment. Pharmacol. Ther. 10 1996 459 467
13. H. Sun, H. Li, A.B. Mason, R.C. Woodworth, P.J. Sadler Competitive binding of bismuth to transferrin and albumin in aqueous solution and in blood plasma J. Biol. Chem. 276 2001 8829 8835
14. S.P. Summers, K.A. Abboud, S.R. Farrah, G.J. Palenik Syntheses and structures of Bismuth(III) complexes with nitrilotriacetic acid, ethylenediaminetetraacetic acid, and diethylenetriaminepentaacetic acid Inorg. Chem. 33 1994 88 92
15. 3+ to human serum transferrin J. Biol. Chem. 271 1996 9483 9489
16. P.J. Sadler, H. Li, H. Sun Coordination chemistry of metals in medicine Target sites for bismuth Coord. Chem. Rev. 185/186 1999 689 709
17. W.R. Harris, B. Yang, S. Abdollahi, Y. Hamada Steric restrictions on the binding of large metal ions to serum transferrin J. Inorg. Biochem. 76 1999 231 242
18. J.G. Grossmann, M. Neu, R.W. Evans, P.F. Lindley, H. Appel, S.S. Hasnain Metal-induced conformational changes in transferrins J. Mol. Biol. 229 1993 585 590
19. W. Zhong, J.A. Parkinson, M. Guo, P.J. Sadler Unusual features for zirconium(IV) binding to human serum transferrin J. Biol. Inorg. Chem. 7 2002 589 599
20. 13C] NMR determination of the order of lobe loading of human transferrin with iron Comparison with other metal ions FEBS Lett. 422 1998 315 320
21. H. Sun, H. Li, A.B. Mason, R.C. Woodworth, P.J. Sadler N-lobe versus C-lobe complexation of bismuth by human transferrin Biochem. J. 337 1999 105 111
22. N. Sreerama, R.W. Woody Circular dichroism of peptides and proteins N. Berova K. Nakanishi R.W. Woody Circular Dichroism Principles and applications 2000 Wiley-VCH New York 601 620
23. S. Tang, R. Maccoll, P.J. Parsons Spectroscopic study of the interaction of aluminum ions with human transferrin J. Inorg. Biochem. 60 1995 175 185
24. G. Battistuzzi, L. Calzolai, L. Messori, M. Sola Metal-induced conformational heterogeneity of transferrins A spectroscopic study of Indium(III) and other metal(III)-substituted transferrins Biochem. Biophys. Res. Commun. 206 1995 161 170
25. K. Mizutani, H. Yamashita, H. Kurokawa, B. Mikami, M. Hirose Alternative structural state of transferrin. The crystallographic analysis of iron-loaded but domain-opened ovotransferrin N-lobe J. Biol. Chem. 274 1999 10190 10194
26. 3+ binding pathway of camel lactoferrin at 2.7 Å resolution J. Biol. Chem. 276 2001 36817 36823
27. H.M. Baker, B.F. Anderson, E.N. Baker Dealing with iron Common structural principles in proteins that transport iron and heme Proc. Natl. Acad. Sci. U.S.A. 100 2003 3579 3583
28. I.A. Kaltashov, S.J. Eyles Studies of biomolecular conformations and conformational dynamics by mass spectrometry Mass Spectrom. Rev. 21 2002 37 71
29. R.D. Shannon Revised effective ionic-radii and systematic studies of interatomic distances in halides and chalcogenides Acta Cryst. A 32 1976 751 767
30. P. Aisen, A. Leibman, J. Zweier Stoichiometric and site characteristics of the binding of iron to human transferrin J. Biol. Chem. 253 1978 1930 1937
31. W.R. Harris, Y. Chen, K. Wein Equilibrium constants for the binding of Indium(III) to human serum transferrin Inorg. Chem. 33 1994 4991 4998