Cidofovir on HHV-8 in BCBL-1 cells

Antiviral Therapy

Volumn 9, Issue 5, 2004, Pages 823-825

  Pica, Francesca ^a   Serafino, Annalucia ^a   Garaci, Enrico ^a   Volpi, Antonio ^b  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b CNR   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CIDOFOVIR; VIRUS DNA;

ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DNA CONTENT; DNA SYNTHESIS; HUMAN; HUMAN HERPESVIRUS 8; KAPOSI SARCOMA; PRIORITY JOURNAL; QUALITATIVE DIAGNOSIS; QUANTITATIVE DIAGNOSIS; TRANSMISSION ELECTRON MICROSCOPY; VIRUS PARTICLE;

ANTIVIRAL AGENTS; CELL LINE, TUMOR; CYTOSINE; DNA, VIRAL; HERPESVIRUS 8, HUMAN; HUMANS; PHOSPHONIC ACIDS; VIRION; VIRUS REPLICATION;

EID: 7244228196     PISSN: 13596535     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Antman K & Chang Y. Kaposi's sarcoma. New England Journal of Medicine 2002; 342:1027-1038.
2. Kedes DH & Ganem D. Sensitivity of Kaposi's sarcoma-associated herpesvirus replication to antiviral drugs. Implications for potential therapy. Journal of Clinical Investigation 1997; 99:2082-2086.
3. Neyts J & De Clercq E. Antiviral drug susceptibility of human herpes virus 8. Antimicrobial Agents & Chemotherapy 1997; 41:2754-2756,
4. Fife K, Gill J, Bourboulia D, Gazzard B, Nelson M & Bower M. Cidofovir for the treatment of Kaposi's sarcoma in an HIV-negative homosexual man. British Journal of Dermatology 1999; 141:1148-1150.
5. Mazzi R, Parisi SG, Sarmati L, Uccella I, Nicastri E, Carolo G, Gatti F, Concia E & Andreoni M. Efficacy of cidofovir on human herpesvirus 8 viraemia and Kaposi's sarcoma progression in two patients with AIDS. AIDS 1997; 15:2061-2063.
6. Little RF, Merced-Galindez F, Staskus K, Whitby D, Aoki Y, Humphrey R, Pluda JM, Marshall V, Walters M, Welles L, Rodriguez-Chavez IR, Pittaluga S, Tosato G & Yarchoan R. A pilot study of cidofovir in patients with Kaposi's sarcoma. Journal of Infectious Diseases 2003; 187:149-153.
7. Simonart T, Noel JC, De Dobbeleer G, Parent D, Van Vooren JP, De Clercq E & Snoeck R. Treatment of classical Kaposi's sarcoma with intralesional injections of cidofovir: report of a case. Journal of Medical Virology 1998; 55:215-218.
8. Pica F, Volpi A, Serafino A, Fraschetti M, Franzese O & Garaci E. Autocrine nerve growth factor is essential for cell survival and viral maturation in HHV-8-infected primary effusion lymphoma cells. Blood 2000; 95:2905-2912.
9. Wachsman M, Petty BG, Cundy KC, Jaffe HS, Fisher PE, Pastelak A & Lietman PS. Pharmacokinetics, safety and bioavailability of HPMPC (cidofovir) in human immunodeficiency virus-infected subjects. Antiviral Research 1996; 29:153-161.
10. Stamey FR, Patel MM, Halloway BP & Pellett PE. Quantitative, fluorogenic probe PCR assay for detection of human herpesvirus 8 DNA in clinical specimens. Journal of Clinical Microbiology 2001; 39:3537-3540.
11. Said JW, Chien K, Tasaka T & Koeffler P. Ultrastructural characterization of Human herpesvirus 8 (Kaposi's sarcoma associated herpesvirus) in Kaposi's sarcoma lesions: electron microscopy permits distinction from cytomegalovirus (CMV). Journal of Pathology 1997; 182:273-281.
12. Irmiere A & Gibson W. Isolation and characterization of a noninfectious virion-like particle released from cells infected with human strains of cytomegalovirus. Virology 1983; 130:118-133.