Staphylococcus aureus 3-hydroxy-3-methylglutaryl-CoA synthase: Crystal structure and mechanism

Journal of Biological Chemistry

Volumn 279, Issue 43, 2004, Pages 44883-44888

  Campobasso, Nino ^a   Patel, Mehul ^c   Wilding, Imogen E ^b   Kallender, Howard ^b   Rosenberg, Martin ^d   Gwynn, Michael N ^b  

^a GLAXOSMITHKLINE   (United States)

^b Microbial Musculoskel P   (United States)

^c Assay Devmt and Compound Profiling   (United States)

^d PROMEGA CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTICS; CHOLESTEROL; CONDENSATION; CRYSTAL STRUCTURE; ENZYMES; ESCHERICHIA COLI;

ACETOACETYL-COA; HOMODIMERS; STAPHYLOCOCCUS AUREUS; SYNTHASE;

COBALT COMPOUNDS;

ACETYL COENZYME A; ASPARAGINE; BACTERIAL ENZYME; CITRATE SYNTHASE; CYSTEINE; GENE PRODUCT; HISTIDINE; HYDROXYMETHYLGLUTARYL COENZYME A SYNTHASE; MONOMER;

ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ASSAY; ENZYME STRUCTURE; ESCHERICHIA COLI; GENE EXPRESSION; NONHUMAN; PRIORITY JOURNAL; PURIFICATION; STAPHYLOCOCCUS AUREUS;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ASPARAGINE; BINDING SITES; CATALYSIS; CHOLESTEROL; CLONING, MOLECULAR; CRYSTALLOGRAPHY, X-RAY; CYSTEINE; DIMERIZATION; ESCHERICHIA COLI; HISTIDINE; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; KINETICS; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY, AMINO ACID; STAPHYLOCOCCUS AUREUS;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; POSIBACTERIA; STAPHYLOCOCCUS; STAPHYLOCOCCUS AUREUS;

EID: 7244223384     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M407882200     Document Type: Article

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