What lies beneath? a lesson for the clinician. intraoperative frozen section appearance of persistent basal cell carcinoma after apparent cure with imiquimod 5% cream: Communications and brief reports

Dermatologic Surgery

Volumn 35, Issue 11, 2009, Pages 1831-1834

  Sukal, Sean A ^a   Mahlberg, Matthew J ^b   Brightman, Lori ^a   Daniel, David R ^c   Mintzis, Medwin M ^b   Geronemus, Roy G ^b  

^a LASER AND SKIN SURGERY CENTER OF NEW YORK   (United States)

^b NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

^c JACOBI MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMIQUIMOD;

ADULT; ARTICLE; BASAL CELL CARCINOMA; CASE REPORT; CHEMOSURGERY; CREAM; DERMIS; FEMALE; FROZEN SECTION; HISTOLOGY; HUMAN; HUMAN TISSUE; INTRAOPERATIVE PERIOD; NOSE; PAPULE; PHYSICIAN; PRIORITY JOURNAL; RECURRENT CANCER; TUMOR BIOPSY; UPPER LIP;

ADMINISTRATION, TOPICAL; ADULT; AMINOQUINOLINES; ANTINEOPLASTIC AGENTS; CARCINOMA, BASAL CELL; FACIAL NEOPLASMS; FEMALE; FROZEN SECTIONS; HUMANS; MIDDLE AGED; MOHS SURGERY; NEOPLASM RECURRENCE, LOCAL; OINTMENTS;

EID: 72349090840     PISSN: 10760512     EISSN: 15244725     Source Type: Journal    
DOI: 10.1111/j.1524-4725.2009.01300.x     Document Type: Article

References (17)

1. Wilkin J. 2004. FDA Approval Letter. Available at : Accessed November 1, 2008.
2. Raasch B, Woolley T. Management of primary superficial basal cell carcinoma. Aust Fam Physician 2006 35 : 455 458.
3. Bath-Hextall FJ, Perkins W, Bong J, Williams HC. Interventions for basal cell carcinoma of the skin. Cochrane Database Syst Rev. 2007;1:CD003412.
4. Eigentler TK, Kamin A, Weide BM, et al. A phase III, randomized, open label study to evaluate the safety and efficacy of imiquimod 5% cream applied thrice weekly for 8 and 12 weeks in the treatment of low-risk nodular basal cell carcinoma. J Am Acad Dermatol 2007 57 : 616 621.
5. Oster-Schmidt C, Altmeyer P, Stücker M. Successful treatment of basal cell carcinoma on the face with imiquimod 5% cream. Acta Derm Venereol 2002 82 : 477.
6. Micali M, Nasca MR, Musumeci ML. Treatment of an extensive superficial basal cell carcinoma of the face with imiquimod 5% cream. Int J Tissue React 2005 27 : 111 114.
7. Marks R, Gebauer K, Shumack S, et al. Imiquimod 5% cream in the treatment of superficial basal cell carcinoma: results of a multicenter 6-week dose response trial. J Am Acad Dermatol 2001 44 : 807 813.
8. Geisse JK, Caro I, Lindholm J, et al. Imiquimod 5% cream for the treatment of superficial basal cell carcinoma: results from two phase III, randomized, vehicle-controlled studies. J Am Acad Dermatol 2004 50 : 722 733.
9. Peris K, Campione E, Micantonio T, et al. Imiquimod treatment of superficial and nodular basal cell carcinoma: 12-week open-label trial. Dermatol Surg 2005 31 : 318 323.
10. Quirk C, Gebauer K, Owens M, et al. Two-year interim results from a 5-year study evaluating clinical recurrence of superficial basal cell carcinoma after treatment with imiquimod 5% cream daily for 6 weeks. Australas J Dermatol 2006 47 : 258 265.
11. Gollnick H, Barona CG, Shumack S, et al. Recurrence rate of superficial basal cell carcinoma following successful treatment with imiquimod 5% cream: interim 2-year results from an ongoing 5-year follow-up study in Europe. Eur J Dermatol 2005 15 : 374 381.
12. Leibovitch I, Huilgol SC, Selva D, et al. Basal cell carcinoma treated with Mohs surgery in Australia II. Outcome at 5-year follow-up. J Am Acad Dermatol 2005 53 : 452 457. (Pubitemid 41195967)
13. Shriner DL, McCoy DK, Goldberg DJ, et al. Mohs micrographic surgery. J Am Acad Dermatol 1998 39 : 79 97.
14. Rowe DE. Comparison of treatment modalities for basal cell carcinoma. Clin Dermatol 1995 13 : 617 620.
15. Silverman MK, Kopf AW, Grin CM, et al. Recurrence rates of treated basal cell carcinomas. Part 2: curettage-electrodesiccation. J Dermatol Surg Oncol 1991 17 : 720 726.
16. Cohen PR, Schulze KE, Nelson BR. Basal cell carcinoma with mixed histology: a possible pathogenesis for recurrent skin cancer. Dermatol Surg 2006 32 : 542 551.
17. Jones MS, Maloney ME, Billingsley EM. The heterogenous nature of in vivo basal cell carcinoma. Dermatol Surg 1998 24 : 881 884.