Doxorubicin induces senescence or apoptosis in rat neonatal cardiomyocytes by regulating the expression levels of the telomere binding factors 1 and 2

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 297, Issue 6, 2009, Pages

  Spallarossa, Paolo ^a   Altieri, Paola ^a   Aloi, Concetta ^a   Garibaldi, Silvano ^a   Barisione, Chiara ^a   Ghigliotti, Giorgio ^a   Fugazza, Giuseppina ^b   Barsotti, Antonio ^a   Brunelli, Claudio ^a  

^a UNIVERSITY OF GENOA   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

Author keywords

Anthracyclines; Mitogen activated protein kinases; P53

Indexed keywords

BETA GALACTOSIDASE; CHECKPOINT KINASE 2; DOXORUBICIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN P53; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; TELOMERIC REPEAT BINDING FACTOR 1; TELOMERIC REPEAT BINDING FACTOR 2;

ANAPHASE; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CYCLE; CELL STRESS; CHROMOSOME ABERRATION; CLINICAL ASSESSMENT; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; GENE EXPRESSION REGULATION; HEART MUSCLE CELL; MICRONUCLEUS; MITOSIS; NEWBORN; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RAT; RNA INTERFERENCE; SENESCENCE;

ANIMALS; ANIMALS, NEWBORN; ANTHRACENES; ANTIBIOTICS, ANTINEOPLASTIC; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BENZOTHIAZOLES; CELL AGING; CELLS, CULTURED; CYTOSKELETON; DOSE-RESPONSE RELATIONSHIP, DRUG; DOXORUBICIN; IMIDAZOLES; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MITOSIS; MYOCYTES, CARDIAC; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHENOTYPE; PROTEIN KINASE INHIBITORS; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-BCL-2; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; RNA INTERFERENCE; TELOMERIC REPEAT BINDING PROTEIN 1; TELOMERIC REPEAT BINDING PROTEIN 2; TIME FACTORS; TOLUENE; TUMOR SUPPRESSOR PROTEIN P53;

EID: 72249121009     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00068.2009     Document Type: Article

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