Should we prescribe blood pressure lowering drugs to every patient with advanced chronic kidney disease? A comment on two recent meta-analyses

Polskie Archiwum Medycyny Wewnetrznej

Volumn 119, Issue 10, 2009, Pages 644-647

  Gross, Peter ^a   Schirutschke, Holger ^a   Barnett, Kerstin ^a  

^a UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

Author keywords

Angiotensin converting enzyme inhibitors; Antihypertensive treatment; Chronic renal failure; Dialysis patients

Indexed keywords

ANTIHYPERTENSIVE AGENT;

CARDIOVASCULAR RISK; CHRONIC KIDNEY DISEASE; CLINICAL TRIAL; DIALYSIS; HUMAN; HYPERTENSION; META ANALYSIS; MORBIDITY; MORTALITY; NOTE; RISK REDUCTION; SYSTEMATIC REVIEW;

EID: 72249116011     PISSN: 00323772     EISSN: None     Source Type: Journal    
DOI: 10.20452/pamw.793     Document Type: Note

References (7)

1. Heerspink HJ, Ninomiya T, Zoungas S, et al. Effect of lowering blood pressure on cardiovascular events and mortality in patients on dialysis: a systematic review and meta-analysis of randomised controlled trials. Lancet. 2009; 373: 1009-1015.
2. Balamuthusamy S, Srinivasan L, Verma M, et al. Renin angiotensin system blockade and cardiovascular outcomes in patients with chronic kidney disease and proteinuria: a meta-analysis. Am Heart J. 2008; 155: 791-805. (Pubitemid 351601744)
3. Foley RN, Parfrey PS, Sarnak MJ. Clinical epidemiology of cardiovascular disease in chronic renal disease. Am J Kidney Dis. 1998; 32 (5 Suppl 3): S112-119.
4. Wanner C, Krane V, März W, et al. Atorvastatin in patients with type 2 diabetes mellitus undergoing hemodialysis. N Engl J Med. 2005; 353: 238-248. (Pubitemid 41058323)
5. Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure. The SOLVD Investigators. N Engl J Med. 1991; 325: 293-302.
6. Yusuf S, Sleight P, Pogue J, et al. Effects of an angiotensin-converting enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators. N Engl J Med. 2000; 342: 145-153.
7. Williams B, Lacy PS, Thom SM, et al. Differential impact of blood pressure-lowering drugs on central aortic pressure and clinical outcomes: principal results of the Conduit Artery Function Evaluation (CAFE) study. Circulation. 2006; 113: 1213-1225. (Pubitemid 43754247)