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Volumn 144, Issue 4, 2009, Pages 339-349

Cytokines in autoimmune bullous skin diseases. Epiphenomena or contribution to pathogenesis?

Author keywords

Cytokines; Interleukins; Pemphigoid, bullous; Pemphigus; Tumor necrosis factor alpha

Indexed keywords

ADALIMUMAB; ALEFACEPT; AZATHIOPRINE; CERTOLIZUMAB PEGOL; CLOBETASOL PROPIONATE; CYCLOPHOSPHAMIDE; CYCLOSPORIN; CYTOKINE; DAPSONE; ETANERCEPT; ETRETIN; GLUCOCORTICOID; GOLIMUMAB; IMMUNOGLOBULIN; IMMUNOGLOBULIN G; INFLIXIMAB; INTERLEUKIN 1; INTERLEUKIN 6; ISIS 104838; LEFLUNOMIDE; METHOTREXATE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISOLONE; PREDNISONE; RITUXIMAB; TUMOR NECROSIS FACTOR ALPHA;

EID: 72249104893     PISSN: 03920488     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (35)

References (97)
  • 1
    • 70349560760 scopus 로고    scopus 로고
    • Autoimmune bullous skin diseases
    • Burgdorf WHC, Plewig G, Wolff HH, Landthaler M, editors. 3rd ed. Heidelberg: Springer
    • Zillikens D. Autoimmune bullous skin diseases. In: Burgdorf WHC, Plewig G, Wolff HH, Landthaler M, editors. Braun-Falco's Dermatology. 3rd ed. Heidelberg: Springer; 2009. p. 641-670
    • (2009) Braun-Falco's Dermatology , pp. 641-670
    • Zillikens, D.1
  • 4
    • 0034519478 scopus 로고    scopus 로고
    • Antibodies against keratinocyte antigens other than desmogleins 1 and 3 can induce pemphigus vulgaris-like lesions
    • Nguyen VT, Ndoye A, Shultz LD, Pittelkow MR, Grando SA. Antibodies against keratinocyte antigens other than desmogleins 1 and 3 can induce pemphigus vulgaris-like lesions. J Clin Invest 2000;106:1467-1479 (Pubitemid 32038585)
    • (2000) Journal of Clinical Investigation , vol.106 , Issue.12 , pp. 1467-1479
    • Nguyen, V.T.1    Ndoye, A.2    Shultz, L.D.3    Pittelkow, M.R.4    Grando, S.A.5
  • 5
    • 0026726642 scopus 로고
    • Autoantibodies against the amino-terminal cadherin-like binding domain of pemphigus vulgaris antigen are pathogenic
    • Amagai M, Karpati S, Prussick R, Klaus-Kovtun V, Stanley JR. Autoantibodies against the amino-terminal cadherin-like binding domain of pemphigus vulgaris antigen are pathogenic. J Clin Invest 1992;90:919-926
    • (1992) J Clin Invest , vol.90 , pp. 919-926
    • Amagai, M.1    Karpati, S.2    Prussick, R.3    Klaus-Kovtun, V.4    Stanley, J.R.5
  • 6
    • 0028321742 scopus 로고
    • Absorption of pathogenic autoantibodies by the extracellular domain of pemphigus vulgaris antigen (Dsg3) produced by baculovirus
    • Amagai M, Hashimoto T, Shimizu N, Nishikawa T. Absorption of pathogenic autoantibodies by the extracellular domain of pemphigus vulgaris antigen (Dsg3) produced by baculovirus. J Clin Invest 1994;94:59-67. (Pubitemid 24218077)
    • (1994) Journal of Clinical Investigation , vol.94 , Issue.1 , pp. 59-67
    • Amagai, M.1    Hashimoto, T.2    Shimizu, N.3    Nishikawa, T.4
  • 7
    • 44449092953 scopus 로고    scopus 로고
    • The desmosome and pemphigus
    • Waschke J. The desmosome and pemphigus. Histochem Cell Biol 2008;130:21-54.
    • (2008) Histochem Cell Biol , vol.130 , pp. 21-54
    • Waschke, J.1
  • 10
    • 0036226456 scopus 로고    scopus 로고
    • Autoantibodies to bullous pemphigoid antigen 180 induce dermal-epidermal separation in cryosections of human skin
    • DOI 10.1046/j.1523-1747.2002.01720.x
    • Sitaru C, Schmidt E, Petermann S, Munteanu LS, Brocker EB, Zillikens D. Autoantibodies to bullous pemphigoid antigen 180 induce dermal-epidermal separation in cryosections of human skin. J Invest Dermatol 2002;118:664-671 (Pubitemid 34309987)
    • (2002) Journal of Investigative Dermatology , vol.118 , Issue.4 , pp. 664-671
    • Sitaru, C.1    Schmidt, E.2    Petermann, S.3    Munteanu, L.S.4    Brocker, E.-B.5    Zillikens, D.6
  • 11
    • 0036784637 scopus 로고    scopus 로고
    • Macrophages, but not T and B lymphocytes, are critical for subepidermal blister formation in experimental bullous pemphigoid: Macrophage-mediated neutrophil infiltration depends on mast cell activation
    • Chen R, Fairley JA, Zhao ML, Giudice GJ, Zillikens D, Diaz LA, et al. Macrophages, but not T and B lymphocytes, are critical for subepidermal blister formation in experimental bullous pemphigoid: macrophage-mediated neutrophil infiltration depends on mast cell activation. J Immunol 2002;169:3987-3992
    • (2002) J Immunol , vol.169 , pp. 3987-3992
    • Chen, R.1    Fairley, J.A.2    Zhao, M.L.3    Giudice, G.J.4    Zillikens, D.5    Diaz, L.A.6
  • 15
    • 47249153519 scopus 로고    scopus 로고
    • Role of cytokines in rheumatoid arthritis: An education in pathophysiology and therapeutics
    • Feldmann M, Maini SR. Role of cytokines in rheumatoid arthritis: an education in pathophysiology and therapeutics. Immunol Rev 2008;223:7-19.
    • (2008) Immunol Rev , vol.223 , pp. 7-19
    • Feldmann, M.1    Maini, S.R.2
  • 16
    • 0028117299 scopus 로고
    • Cytokine therapeutics: Lessons from interferon alpha
    • Gutterman JU. Cytokine therapeutics: lessons from interferon alpha. Proc Natl Acad Sci U S A 1994;91:1198-1205
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 1198-1205
    • Gutterman, J.U.1
  • 17
    • 0032413352 scopus 로고    scopus 로고
    • Anti-TNFalpha therapy is useful in rheumatoid arthritis and Crohn's disease: Analysis of the mechanism of action predicts utility in other diseases
    • DOI 10.1016/S0041-1345(98)01365-7, PII S0041134598013657
    • Feldman M, Taylor P, Paleolog E, Brennan FM, Maini RN. Anti-TNF alpha therapy is useful in rheumatoid arthritis and Crohn's disease: analysis of the mechanism of action predicts utility in other diseases. Transplant Proc 1998;30:4126-4127 (Pubitemid 29013179)
    • (1998) Transplantation Proceedings , vol.30 , Issue.8 , pp. 4126-4127
    • Feldman, M.1    Taylor, P.2    Paleolog, E.3    Brennan, F.M.4    Maini, R.N.5
  • 18
    • 0034729950 scopus 로고    scopus 로고
    • Etanercept in the treatment of psoriatic arthritis and psoriasis: A randomised trial
    • Mease PJ, Goffe BS, Metz J, VanderStoep A, Finck B, Burge DJ. Etanercept in the treatment of psoriatic arthritis and psoriasis: a randomised trial. Lancet 2000;356:385-390 (Pubitemid 30487495)
    • (2000) Lancet , vol.356 , Issue.9227 , pp. 385-390
    • Mease, P.J.1    Goffe, B.S.2    Metz, J.3    Vanderstoep, A.4    Finck, B.5    Burge, D.J.6
  • 21
    • 0021681058 scopus 로고
    • Human tumour necrosis factor: Precursor structure, expression and homology to lymphotoxin
    • Pennica D, Nedwin GE, Hayflick JS, Seeburg PH, Derynck R, Palladino MA, et al. Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin. Nature 1984;312:724-729
    • (1984) Nature , vol.312 , pp. 724-729
    • Pennica, D.1    Nedwin, G.E.2    Hayflick, J.S.3    Seeburg, P.H.4    Derynck, R.5    Palladino, M.A.6
  • 22
    • 1542376173 scopus 로고    scopus 로고
    • The transfer of a laboratory based hypothesis to a clinically useful therapy: The development of anti-TNF therapy of rheumatoid arthritis
    • DOI 10.1016/j.berh.2003.09.010
    • Feldmann M, Brennan FM, Williams RO, Woody JN, Maini RN. The transfer of a laboratory based hypothesis to a clinically useful therapy: the development of anti-TNF therapy of rheumatoid arthritis. Best Pract Res Clin Rheumatol 2004;18:59-80. (Pubitemid 38324659)
    • (2004) Best Practice and Research: Clinical Rheumatology , vol.18 , Issue.1 , pp. 59-80
    • Feldmann, M.1    Brennan, F.M.2    Williams, R.O.3    Woody, J.N.4    Maini, R.N.5
  • 23
    • 0033543754 scopus 로고    scopus 로고
    • Transmembrane tumor necrosis factor (TNF)-alpha inhibits adipocyte differentiation by selectively activating TNF receptor 1
    • Xu H, Sethi JK, Hotamisligil GS. Transmembrane tumor necrosis factor TNF)-alpha inhibits adipocyte differentiation by selectively activating TNF receptor 1. J Biol Chem 1999;274:26287-26295 (Pubitemid 129520059)
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.37 , pp. 26287-26295
    • Xu, H.1    Sethi, J.K.2    Hotamisligil, G.S.3
  • 24
    • 0025149247 scopus 로고
    • A nonsecretable cell surface mutant of tumor necrosis factor (TNF) kills by cell-to-cell contact
    • Perez C, Albert I, DeFay K, Zachariades N, Gooding L, Kriegler M. A nonsecretable cell surface mutant of tumor necrosis factor (TNF) kills by cell-to-cell contact. Cell 1990;63:251-258
    • (1990) Cell , vol.63 , pp. 251-258
    • Perez, C.1    Albert, I.2    DeFay, K.3    Zachariades, N.4    Gooding, L.5    Kriegler, M.6
  • 26
    • 0028811230 scopus 로고
    • Effects of recombinant dimeric TNF receptor on human inflammatory responses following intravenous endotoxin administration
    • Suffredini AF, Reda D, Banks SM, Tropea M, Agosti JM, Miller R. Effects of recombinant dimeric TNF receptor on human inflammatory responses following intravenous endotoxin administration. J Immunol 1995;155:5038-5045
    • (1995) J Immunol , vol.155 , pp. 5038-5045
    • Suffredini, A.F.1    Reda, D.2    Banks, S.M.3    Tropea, M.4    Agosti, J.M.5    Miller, R.6
  • 27
    • 0036201985 scopus 로고    scopus 로고
    • Long term anti-tumour necrosis factor alpha monotherapy in rheumatoid arthritis: Effect on radiological course and prognostic value of markers of cartilage turnover and endothelial activation
    • den Broeder AA, Joosten LA, Saxne T, Heinegard D, Fenner H, Miltenburg AM et al. Long term anti-tumour necrosis factor alpha monotherapy in rheumatoid arthritis: effect on radiological course and prognostic value of markers of cartilage turnover and endothelial activation. Ann Rheum Dis 2002;61:311-318
    • (2002) Ann Rheum Dis , vol.61 , pp. 311-318
    • Den Broeder, A.A.1    Joosten, L.A.2    Saxne, T.3    Heinegard, D.4    Fenner, H.5    Miltenburg, A.M.6
  • 28
    • 0031435327 scopus 로고    scopus 로고
    • Cytokines in the sera of patients with pemphigus vulgaris: Interleukin-6 and tumour necrosis factor-alpha levels are significantly increased as compared to healthy subjects and correlate with disease activity
    • D'Auria L, Bonifati C, Mussi A, D'Agosto G, De SC, Giacalone B et al. Cytokines in the sera of patients with pemphigus vulgaris: interleukin-6 and tumour necrosis factor-alpha levels are significantly increased as compared to healthy subjects and correlate with disease activity. Eur Cytokine Netw 1997;8:383-387
    • (1997) Eur Cytokine Netw , vol.8 , pp. 383-387
    • D'Auria, L.1    Bonifati, C.2    Mussi, A.3    D'Agosto, G.4    De, S.C.5    Giacalone, B.6
  • 29
    • 0033303154 scopus 로고    scopus 로고
    • Anti-intercellular substance antibody log titres are correlated with serum concentrations of interleukin-6, interleukin-15 and tumor necrosis factor-alpha in patients with Pemphigus vulgaris relationships with peripheral blood neutrophil counts, disease severity and duration and patients' age
    • Ameglio F, D'Auria L, Cordiali-Fei P, Trento E, D'Agosto G, Mastroianni A et al. Anti-intercellular substance antibody log titres are correlated with serum concentrations of interleukin-6, interleukin-15 and tumor necrosis factor-alpha in patients with Pemphigus vulgaris relationships with peripheral blood neutrophil counts, disease severity and duration and patients' age. J Biol Regul Homeost Agents 1999;13:220-224
    • (1999) J Biol Regul Homeost Agents , vol.13 , pp. 220-224
    • Ameglio, F.1    D'Auria, L.2    Cordiali-Fei, P.3    Trento, E.4    D'Agosto, G.5    Mastroianni, A.6
  • 30
    • 0033117980 scopus 로고    scopus 로고
    • ICAM-1, ELAM-1, TNF-alpha and IL-6 in serum and blister liquid of pemphigus vulgaris patients
    • Alecu M, Alecu S, Coman G, Galatescu E, Ursaciuc C. ICAM-1, ELAM-1, TNF-alpha and IL-6 in serum and blister liquid of pemphigus vulgaris patients. Roum Arch Microbiol Immunol 1999;58:121-130
    • (1999) Roum Arch Microbiol Immunol , vol.58 , pp. 121-130
    • Alecu, M.1    Alecu, S.2    Coman, G.3    Galatescu, E.4    Ursaciuc, C.5
  • 32
    • 0034040593 scopus 로고    scopus 로고
    • In vitro and in vivo expression of interleukin-1 alpha and tumor necrosis factor-alpha mRNA in pemphigus vulgaris: Interleukin-1 alpha and tumor necrosis factor-alpha are involved in acantholysis
    • Feliciani C, Toto P, Amerio P, Pour SM, Coscione G, Shivji G et al. In vitro and in vivo expression of interleukin-1 alpha and tumor necrosis factor-alpha mRNA in pemphigus vulgaris: interleukin-1 alpha and tumor necrosis factor-alpha are involved in acantholysis. J Invest Dermatol 2000;114:71-77
    • (2000) J Invest Dermatol , vol.114 , pp. 71-77
    • Feliciani, C.1    Toto, P.2    Amerio, P.3    Pour, S.M.4    Coscione, G.5    Shivji, G.6
  • 34
    • 0023233253 scopus 로고
    • Involvement of urokinase-type plasminogen activator in acantholysis induced by pemphigus IgG
    • Morioka S, Lazarus GS, Jensen PJ. Involvement of urokinase-type plasminogen activator in acantholysis induced by pemphigus IgG. J Invest Dermatol 1987;89:474-477
    • (1987) J Invest Dermatol , vol.89 , pp. 474-477
    • Morioka, S.1    Lazarus, G.S.2    Jensen, P.J.3
  • 36
    • 0042063736 scopus 로고    scopus 로고
    • Urokinase plasminogen activator mRNA is induced by IL-1alpha and TNF-alpha in in vitro acantholysis
    • Feliciani C, Toto P, Wang B, Sauder DN, Amerio P, Tulli A. Urokinase plasminogen activator mRNA is induced by IL-1alpha and TNF-alpha in in vitro acantholysis. Exp Dermatol 2003;12:466-471
    • (2003) Exp Dermatol , vol.12 , pp. 466-471
    • Feliciani, C.1    Toto, P.2    Wang, B.3    Sauder, D.N.4    Amerio, P.5    Tulli, A.6
  • 37
    • 0032809239 scopus 로고    scopus 로고
    • Pemphigus vulgaris and pemphigus foliaceus antibodies are pathogenic in plasminogen activator knockout mice
    • Mahoney MG, Wang ZH, Stanley JR. Pemphigus vulgaris and pemphigus foliaceus antibodies are pathogenic in plasminogen activator knockout mice. J Invest Dermatol 1999;113:22-25
    • (1999) J Invest Dermatol , vol.113 , pp. 22-25
    • Mahoney, M.G.1    Wang, Z.H.2    Stanley, J.R.3
  • 39
  • 41
    • 35448994836 scopus 로고    scopus 로고
    • Tumour necrosis factor-alpha in conjunctivae affected by ocular cicatricial pemphigoid
    • DOI 10.1111/j.1600-0420.2007.00941.x
    • Cordero CM, Yilmaz T, Foster CS. Tumour necrosis factor-alpha in conjunctivae affected by ocular cicatricial pemphigoid. Acta Ophthalmol Scand 2007;85:753-755 (Pubitemid 47616792)
    • (2007) Acta Ophthalmologica Scandinavica , vol.85 , Issue.7 , pp. 753-755
    • Coma, M.C.1    Yilmaz, T.2    Foster, C.S.3
  • 42
    • 72249110288 scopus 로고    scopus 로고
    • Tumour Necrosis Factor-{alpha in Ocular Mucous Membrane Pemphigoid and its effect on Conjunctival Fibroblasts
    • Jun 3. [Epub ahead of print]
    • Saw VP, Dart RJ, Galatowicz G, Daniels JT, Dart J, Calder VL. Tumour Necrosis Factor-{alpha) in Ocular Mucous Membrane Pemphigoid and its effect on Conjunctival Fibroblasts. Invest Ophthalmol Vis Sci 2009 Jun 3. [Epub ahead of print]
    • (2009) Invest Ophthalmol Vis Sci
    • Saw, V.P.1    Dart, R.J.2    Galatowicz, G.3    Daniels, J.T.4    Dart, J.5    Calder, V.L.6
  • 43
    • 70349497499 scopus 로고    scopus 로고
    • Development of bullous pemphigoid during treatment of psoriasis with adalimumab
    • May 5. [Epub ahead of print]
    • Stausbol-Gron B, Deleuran M, Sommer HE, Kragballe K. Development of bullous pemphigoid during treatment of psoriasis with adalimumab. Clin Exp Dermatol 2009 May 5. [Epub ahead of print]
    • (2009) Clin Exp Dermatol
    • Stausbol-Gron, B.1    Deleuran, M.2    Sommer, H.E.3    Kragballe, K.4
  • 44
    • 18144417512 scopus 로고    scopus 로고
    • Lymphocyte trafficking to inflamed skin - Molecular mechanisms and implications for therapeutic target molecules
    • DOI 10.1517/14728222.9.2.225
    • Schön M, Ludwig RJ. Leukocyte trafficking to inflamed skin - molecular mechanisms and implications for therapeutic target mole- cules. Expert Opin Ther Targets 2005;9:225-243 (Pubitemid 40613865)
    • (2005) Expert Opinion on Therapeutic Targets , vol.9 , Issue.2 , pp. 225-243
    • Schon, M.P.1    Ludwig, R.J.2
  • 47
    • 31544441368 scopus 로고    scopus 로고
    • Differential roles for beta2 integrins in experimental autoimmune bullous pemphigoid
    • DOI 10.1182/blood-2005-08-3123
    • Liu Z, Zhao M, Li N, Diaz LA, Mayadas TN. Differential roles for beta2 integrins in experimental autoimmune bullous pemphigoid. Blood 2006;107:1063-1069 (Pubitemid 43156306)
    • (2006) Blood , vol.107 , Issue.3 , pp. 1063-1069
    • Liu, Z.1    Zhao, M.2    Li, N.3    Diaz, L.A.4    Mayadas, T.N.5
  • 48
    • 0036467389 scopus 로고    scopus 로고
    • IL-1 and IL-18 receptors, and their extended family
    • Sims JE. IL-1 and IL-18 receptors, and their extended family. Curr Opin Immunol 2002;14:117-122
    • (2002) Curr Opin Immunol , vol.14 , pp. 117-122
    • Sims, J.E.1
  • 49
    • 2642559875 scopus 로고    scopus 로고
    • Targeting IL-1 in inflammatory disease: New opportunities for therapeutic intervention
    • Braddock M, Quinn A. Targeting IL-1 in inflammatory disease: new opportunities for therapeutic intervention. Nat Rev Drug Discov 2004;3:330-339 (Pubitemid 38499760)
    • (2004) Nature Reviews Drug Discovery , vol.3 , Issue.4 , pp. 330-339
    • Braddock, M.1    Quinn, A.2
  • 50
    • 0029009910 scopus 로고
    • Molecular cloning and characterization of a second subunit of the interleukin 1 receptor complex
    • Greenfeder SA, Nunes P, Kwee L, Labow M, Chizzonite RA, Ju G. Molecular cloning and characterization of a second subunit of the interleukin 1 receptor complex. J Biol Chem 1995;270:13757-13765
    • (1995) J Biol Chem , vol.270 , pp. 13757-13765
    • Greenfeder, S.A.1    Nunes, P.2    Kwee, L.3    Labow, M.4    Chizzonite, R.A.5    Ju, G.6
  • 51
    • 0343278979 scopus 로고    scopus 로고
    • Interleukin 1 receptor accessory protein (IL-1RAcP) is necessary for centrally mediated neuroendocrine and immune responses to IL-1beta
    • DOI 10.1016/S0165-5728(00)00331-3, PII S0165572800003313
    • Liege S, Laye S, Li KS, Moze E, Neveu PJ. Interleukin 1 receptor accessory protein (IL-1RAcP) is necessary for centrally mediated neuroendocrine and immune responses to IL-1beta. J Neuroimmunol 2000;110:134-139 (Pubitemid 30750465)
    • (2000) Journal of Neuroimmunology , vol.110 , Issue.1-2 , pp. 134-139
    • Liege, S.1    Laye, S.2    Li, K.-S.3    Moze, E.4    Neveu, P.J.5
  • 52
    • 0036839416 scopus 로고    scopus 로고
    • Potential therapeutic uses of interleukin 1 receptor antagonists in human diseases
    • DOI 10.1136/ard.61.11.960
    • Hallegua DS, Weisman MH. Potential therapeutic uses of interleukin 1 receptor antagonists in human diseases. Ann Rheum Dis 2002;61:960-967 (Pubitemid 35221682)
    • (2002) Annals of the Rheumatic Diseases , vol.61 , Issue.11 , pp. 960-967
    • Hallegua, D.S.1    Weisman, M.H.2
  • 54
    • 0028239555 scopus 로고
    • Recombinant human interleukin 1 receptor antagonist in the treatment of patients with sepsis syndrome. Results from a randomized, double-blind, placebo-controlled trial
    • Phase III rhIL-1ra Sepsis Syndrome Study Group
    • Fisher CJ, Jr., Dhainaut JF, Opal SM, Pribble JP, Balk RA, Slotman GJ et al. Recombinant human interleukin 1 receptor antagonist in the treatment of patients with sepsis syndrome. Results from a randomized, double-blind, placebo-controlled trial. Phase III rhIL-1ra Sepsis Syndrome Study Group. JAMA 1994;271:1836-1843
    • (1994) JAMA , vol.271 , pp. 1836-1843
    • Fisher Jr., C.J.1    Dhainaut, J.F.2    Opal, S.M.3    Pribble, J.P.4    Balk, R.A.5    Slotman, G.J.6
  • 55
    • 0029943271 scopus 로고    scopus 로고
    • Dose-range and dose-frequency study of recombinant human interleukin-1 receptor antagonist in patients with rheumatoid arthritis
    • The IL-1Ra Arthritis Study Group
    • Campion GV, Lebsack ME, Lookabaugh J, Gordon G, Catalano M. Dose-range and dose-frequency study of recombinant human interleukin-1 receptor antagonist in patients with rheumatoid arthritis. The IL-1Ra Arthritis Study Group. Arthritis Rheum 1996;39:1092-101.
    • (1996) Arthritis Rheum , vol.39 , pp. 1092-1101
    • Campion, G.V.1    Lebsack, M.E.2    Lookabaugh, J.3    Gordon, G.4    Catalano, M.5
  • 57
    • 84898706954 scopus 로고    scopus 로고
    • Anakinra - open studies at 2009, July 14
    • Anakinra - open studies at ClinicalTrials.gov. http://clinicaltrialsgov/ ct2/results?term=anakinra&recr=Open2009, July 14
  • 58
    • 58849156486 scopus 로고    scopus 로고
    • Canakinumab, a fully-human mAb against IL-1 beta for the potential treatment of inflammatory disorders
    • Church LD, McDermott MF. Canakinumab, a fully-human mAb against IL-1 beta for the potential treatment of inflammatory disorders. Curr Opin Mol Ther 2009;11:81-89
    • (2009) Curr Opin Mol Ther , vol.11 , pp. 81-89
    • Church, L.D.1    McDermott, M.F.2
  • 61
    • 84898709361 scopus 로고    scopus 로고
    • Canakinumab - open studies at 2009, July 12
    • Canakinumab - open studies at ClinicalTrials.gov. http:// clinicaltrialsgov/ct2/results?term=canakinumab 2009, July 12
  • 63
    • 39749119781 scopus 로고    scopus 로고
    • Cytokine profiles in pemphigus vulgaris patients treated with intravenous immunoglobulins as compared to conventional immunosuppressive therapy
    • Keskin DB, Stern JN, Fridkis-Hareli M, Razzaque AA. Cytokine profiles in pemphigus vulgaris patients treated with intravenous immunoglobulins as compared to conventional immunosuppressive therapy. Cytokine 2008;41:315-321
    • (2008) Cytokine , vol.41 , pp. 315-321
    • Keskin, D.B.1    Stern, J.N.2    Fridkis-Hareli, M.3    Razzaque, A.A.4
  • 64
    • 0034904154 scopus 로고    scopus 로고
    • Pemphigus vulgaris: The role of IL-1 and IL-1 receptor antagonist in pathogenesis and effects of intravenous immunoglobulin on their production
    • DOI 10.1006/clim.2001.5061
    • Bhol KC, Desai A, Kumari S, Colon JE, Ahmed AR. Pemphigus vulgaris: the role of IL-1 and IL-1 receptor antagonist in pathogenesis and effects of intravenous immunoglobulin on their production. Clin Immunol 2001;100:172-180 (Pubitemid 32703422)
    • (2001) Clinical Immunology , vol.100 , Issue.2 , pp. 172-180
    • Bhol, K.C.1    Desai, A.2    Kumari, S.3    Colon, J.E.4    Ahmed, A.R.5
  • 65
    • 0031900029 scopus 로고    scopus 로고
    • Cytokine pattern in blister fluid and serum of patients with bullous pemphigoid: Relationships with disease intensity
    • DOI 10.1046/j.1365-2133.1998.02169.x
    • Ameglio F, D'Auria L, Bonifati C, Ferraro C, Mastroianni A, Giacalone B. Cytokine pattern in blister fluid and serum of patients with bullous pemphigoid: Relationships with disease intensity. Br J Dermatol 1998;138:611-614 (Pubitemid 28212243)
    • (1998) British Journal of Dermatology , vol.138 , Issue.4 , pp. 611-614
    • Ameglio, F.1    D'Auria, L.2    Bonifati, C.3    Ferraro, C.4    Mastroianni, A.5    Giacalone, B.6
  • 66
  • 70
    • 0036899812 scopus 로고    scopus 로고
    • Therapeutic benefit of blocking interleukin-6 activity with an anti-interleukin-6 receptor monoclonal antibody in rheumatoid arthritis: A randomized, double-blind, placebo-controlled, dose-escalation trial
    • Choy EH, Isenberg DA, Garrood T, Farrow S, Ioannou Y, Bird H et al. Therapeutic benefit of blocking interleukin-6 activity with an anti-interleukin-6 receptor monoclonal antibody in rheumatoid arthritis: a randomized, double-blind, placebo-controlled, dose-escalation trial. Arthritis Rheum 2002;46:3143-3150
    • (2002) Arthritis Rheum , vol.46 , pp. 3143-3150
    • Choy, E.H.1    Isenberg, D.A.2    Garrood, T.3    Farrow, S.4    Ioannou, Y.5    Bird, H.6
  • 71
    • 0026620124 scopus 로고
    • Autoimmune features in atherosclerotic ischemic cardiomyopathy
    • Paris
    • Rorito S, Magrini L. Autoimmune features in atherosclerotic ischemic cardiomyopathy. Allerg Immunol (Paris) 1992;24:336-341
    • (1992) Allerg Immunol , vol.24 , pp. 336-341
    • Rorito, S.1    Magrini, L.2
  • 72
    • 84898705765 scopus 로고    scopus 로고
    • Open studies with tocilizumab on 2009 July 12
    • Open studies with tocilizumab on ClinicalTriaIs.gov. http:// clinicaltrialsgov/ct2/results?term=tocilizumab&recr=Open&show-flds=Y, 2009 July 12
  • 73
    • 0032978423 scopus 로고    scopus 로고
    • Elevated serum levels of interleukin-6 in paraneoplastic pemphigus
    • Nousari HC, Kimyai-Asadi A, Anhalt GJ. Elevated serum levels of interleukin-6 in paraneoplastic pemphigus. J Invest Dermatol 1999;112:396-398
    • (1999) J Invest Dermatol , vol.112 , pp. 396-398
    • Nousari, H.C.1    Kimyai-Asadi, A.2    Anhalt, G.J.3
  • 76
    • 0030635274 scopus 로고    scopus 로고
    • Increased serum levels of interleukin (IL)-5, IL-6 and IL-8 in bullous pemphigoid
    • Inaoki M, Takehara K. Increased serum levels of interleukin (IL)-5, IL-6 and IL-8 in bullous pemphigoid. J Dermatol Sci 1998;16:152-7.
    • (1998) J Dermatol Sci , vol.16 , pp. 152-157
    • Inaoki, M.1    Takehara, K.2
  • 77
    • 0033747517 scopus 로고    scopus 로고
    • Autoantibodies to BP180 associated with bullous pemphigoid release interleukin-6 and interleukin-8 from cultured human keratinocytes
    • Schmidt E, Reimer S, Kruse N, Jainta S, Brocker EB, Marinkovich MP et al. Autoantibodies to BP180 associated with bullous pemphigoid release interleukin-6 and interleukin-8 from cultured human keratinocytes. J Invest Dermatol 2000;115:842-848
    • (2000) J Invest Dermatol , vol.115 , pp. 842-848
    • Schmidt, E.1    Reimer, S.2    Kruse, N.3    Jainta, S.4    Brocker, E.B.5    Marinkovich, M.P.6
  • 79
    • 67449132596 scopus 로고    scopus 로고
    • A comparison of two regimens of topical corticosteroids in the treatment of patients with bullous pemphigoid: A multicenter randomized study
    • Joly P, Roujeau JC, Benichou J, Delaporte E, D'Incan M, Dreno B, et al. A comparison of two regimens of topical corticosteroids in the treatment of patients with bullous pemphigoid: a multicenter randomized study. J Invest Dermatol 2009;129:1681-1687
    • (2009) J Invest Dermatol , vol.129 , pp. 1681-1687
    • Joly, P.1    Roujeau, J.C.2    Benichou, J.3    Delaporte, E.4    D'Incan, M.5    Dreno, B.6
  • 80
    • 0036796777 scopus 로고    scopus 로고
    • Efficacy of a novel PEGylated humanized anti-TNF fragment (CDP870) in patients with rheumatoid arthritis: A phase II double-blinded, randomized, dose-escalating trial
    • Choy EH, Hazleman B, Smith M, Moss K, Lisi L, Scott DG et al. Efficacy of a novel PEGylated humanized anti-TNF fragment (CDP870) in patients with rheumatoid arthritis: a phase II double-blinded, randomized, dose-escalating trial. Rheumatology (Oxford) 2002;41: 1133-1137 (Pubitemid 35203540)
    • (2002) Rheumatology , vol.41 , Issue.10 , pp. 1133-1137
    • Choy, E.H.S.1    Hazleman, B.2    Smith, M.3    Moss, K.4    Lisi, L.5    Scott, D.G.I.6    Patel, J.7    Sopwith, M.8    Isenberg, D.A.9
  • 82
    • 0036896204 scopus 로고    scopus 로고
    • Phase I trial of ISIS 104838, a 2′-methoxyethyl modified antisense oligonucleotide targeting tumor necrosis factor-alpha
    • Sewell KL, Geary RS, Baker BF, Glover JM, Mant TG, Yu RZ et al. Phase I trial of ISIS 104838, a 2′-methoxyethyl modified antisense oligonucleotide targeting tumor necrosis factor-alpha. J Pharmacol Exp Ther 2002;303:1334-1343
    • (2002) J Pharmacol Exp Ther , vol.303 , pp. 1334-1343
    • Sewell, K.L.1    Geary, R.S.2    Baker, B.F.3    Glover, J.M.4    Mant, T.G.5    Yu, R.Z.6
  • 84
    • 65249137637 scopus 로고    scopus 로고
    • Golimumab, a new human tumor necrosis factor alpha antibody, administered every four weeks as a subcutaneous injection in psoriatic arthritis: Twenty-four-week efficacy and safety results of a randomized, placebo-controlled study
    • Kavanaugh A, McInnes I, Mease P, Krueger GG, Gladman D, Gomez-Reino J et al. Golimumab, a new human tumor necrosis factor alpha antibody, administered every four weeks as a subcutaneous injection in psoriatic arthritis: Twenty-four-week efficacy and safety results of a randomized, placebo-controlled study. Arthritis Rheum 2009;60:976-986
    • (2009) Arthritis Rheum , vol.60 , pp. 976-986
    • Kavanaugh, A.1    McInnes, I.2    Mease, P.3    Krueger, G.G.4    Gladman, D.5    Gomez-Reino, J.6
  • 85
    • 7744242111 scopus 로고    scopus 로고
    • Treatment of recalcitrant pemphigus vulgaris with the tumor necrosis factor alpha antagonist etanercept
    • Berookhim B, Fischer HD, Weinberg JM. Treatment of recalcitrant pemphigus vulgaris with the tumor necrosis factor alpha antagonist etanercept. Cutis 2004;74:245-247 (Pubitemid 39462890)
    • (2004) Cutis , vol.74 , Issue.4 , pp. 245-247
    • Berookhim, B.1    Fischer, H.D.2    Weinberg, J.M.3
  • 86
    • 21844437632 scopus 로고    scopus 로고
    • Successful treatment of recalcitrant pemphigus vulgaris and pemphigus vegetans with etanercept and carbon dioxide laser
    • Lin MH, Hsu CK, Lee JY. Successful treatment of recalcitrant pemphigus vulgaris and pemphigus vegetans with etanercept and carbon dioxide laser. Arch Dermatol 2005;141:680-682
    • (2005) Arch Dermatol , vol.141 , pp. 680-682
    • Lin, M.H.1    Hsu, C.K.2    Lee, J.Y.3
  • 89
    • 24144491556 scopus 로고    scopus 로고
    • Rapid control of therapy-refractory pemphigus vulgaris by treatment with the tumour necrosis factor-alpha inhibitor infliximab [6]
    • DOI 10.1111/j.1365-2133.2005.06744.x
    • Jacobi A, Shuler G, Hertl M. Rapid control of therapy-refractory pemphigus vulgaris by treatment with the tumour necrosis factor-alpha inhibitor infliximab. Br J Dermatol 2005;153:448-449 (Pubitemid 41228454)
    • (2005) British Journal of Dermatology , vol.153 , Issue.2 , pp. 448-449
    • Jacobi, A.1    Schuler, G.2    Hertl, M.3
  • 90
    • 23944441181 scopus 로고    scopus 로고
    • Rapid response of IgA pemphigus of the subcorneal pustular dermatosis subtype to treatment with adalimumab and mycophenolate mofetil
    • Howell SM, Bessinger GT, Altman CE, Belnap CM. Rapid response of IgA pemphigus of the subcorneal pustular dermatosis subtype to treatment with adalimumab and mycophenolate mofetil. J Am Acad Dermatol 2005;53:541-543
    • (2005) J Am Acad Dermatol , vol.53 , pp. 541-543
    • Howell, S.M.1    Bessinger, G.T.2    Altman, C.E.3    Belnap, C.M.4
  • 92
    • 32644449004 scopus 로고    scopus 로고
    • Treatment of coexisting bullous pemphigoid and psoriasis with the tumor necrosis factor antagonist etanercept [2]
    • DOI 10.1016/j.jaad.2005.10.055, PII S0190962205045779
    • Yamauchi PS, Lowe NJ, Gindi V. Treatment of coexsiting bullous pemphigoid and psoriasis with the tumor necrosis factor antagonist etanercept. J Am Acad Dermatol 2005;54:S121-S122. (Pubitemid 43243484)
    • (2006) Journal of the American Academy of Dermatology , vol.54 , Issue.3 SUPPL. 2
    • Yamauchi, P.S.1    Lowe, N.J.2    Gindi, V.3
  • 93
    • 33751210090 scopus 로고    scopus 로고
    • Successful treatment of mucous membrane pemphigoid with etanercept in 3 patients
    • DOI 10.1001/archderm.142.11.1457
    • Canizares MJ, Smith DI, Conners MS, Maverick KJ, Heffernan MP. Successful treatment of mucous membrane pemphigoid with etanercept in 3 patients. Arch Dermatol 2006;142:1457-1461 (Pubitemid 44790639)
    • (2006) Archives of Dermatology , vol.142 , Issue.11 , pp. 1457-1461
    • Canizares, M.J.1    Smith, D.I.2    Conners, M.S.3    Maverick, K.J.4    Heffernan, M.P.5
  • 94
    • 33846857347 scopus 로고    scopus 로고
    • Treatment of ocular cicatricial pemphigoid with the tumour necrosis factor alpha antagonist etanercept
    • Prey S, Robert PY, Drouet M, Sparsa A, Roux C, Bonnetblanc JM et al. Treatment of ocular cicatricial pemphigoid with the tumour necrosis factor alpha antagonist etanercept. Acta Derm Venereol 2007;87:74-75
    • (2007) Acta Derm Venereol , vol.87 , pp. 74-75
    • Prey, S.1    Robert, P.Y.2    Drouet, M.3    Sparsa, A.4    Roux, C.5    Bonnetblanc, J.M.6
  • 95
    • 35948930238 scopus 로고    scopus 로고
    • Successful biologic treatment of ocular mucous membrane pemphigoid with anti-TNF-alpha [7]
    • DOI 10.1038/sj.eye.6702948, PII 6702948
    • John H, Whallett A, Quinlan M. Successful biologic treatment of ocular mucous membrane pemphigoid with anti-TNF-alpha. Eye 2007;21:1434-1435 (Pubitemid 350066484)
    • (2007) Eye , vol.21 , Issue.11 , pp. 1434-1435
    • John, H.1    Whallett, A.2    Quinlan, M.3
  • 96
    • 38849175499 scopus 로고    scopus 로고
    • A biological approach in a patient with psoriasis and bullous pemphigoid associated with losartan therapy
    • DOI 10.1111/j.1365-2230.2007.02603.x
    • Saraceno R, Citarella L, Spallone G, Chimenti S. A biological approach in a patient with psoriasis and bullous pemphigoid associated with losartan therapy. Clin Exp Dermatol 2008;33:154-155 (Pubitemid 351197207)
    • (2008) Clinical and Experimental Dermatology , vol.33 , Issue.2 , pp. 154-155
    • Saraceno, R.1    Citarella, L.2    Spallone, G.3    Chimenti, S.4
  • 97
    • 33750065694 scopus 로고    scopus 로고
    • Successful treatment of mucous membrane pemphigoid with infliximab
    • Heffernan MP, Bentley DD. Successful treatment of mucous membrane pemphigoid with infliximab. Arch Dermatol 2006;142:1268-70.
    • (2006) Arch Dermatol , vol.142 , pp. 1268-1270
    • Heffernan, M.P.1    Bentley, D.D.2


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