Progressive improvement in cardiac performance with continuous aortic flow augmentation (aortic flow therapy) in patients hospitalized with severe heart failure: Results of the Multicenter Trial of the Orqis Medical Cancion System for the Enhanced Treatment of Heart Failure Unresponsive to Medical Therapy (MOMENTUM)

Journal of Heart and Lung Transplantation

Volumn 29, Issue 1, 2010, Pages 86-92

  Zile, Michael R ^a   Colombo, Paolo C ^b   Mehra, Mandeep ^c   Greenberg, Barry ^d   Brown, Scott ^e   Konstam, Marvin A ^f  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

^c UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e Integra Group   (United States)

^f TUFTS UNIVERSITY   (United States)

Author keywords

heart failure; heart assist device; hemodynamics; systolic function

Indexed keywords

ALDOSTERONE; ANGIOTENSIN RECEPTOR ANTAGONIST; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DOBUTAMINE; DOPAMINE; FUROSEMIDE; GLYCERYL TRINITRATE; INOTROPIC AGENT; MILRINONE; NESIRITIDE; NITROPRUSSIDE SODIUM; VASODILATOR AGENT;

ADULT; AORTA FLOW; ARTICLE; BETA ADRENERGIC RECEPTOR BLOCKING; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROL GROUP; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; HEART FAILURE; HEART INDEX; HEART LEFT VENTRICLE EJECTION FRACTION; HEART PERFORMANCE; HEART STROKE VOLUME; HEMODYNAMICS; HOSPITAL PATIENT; HUMAN; KIDNEY FUNCTION; MAJOR CLINICAL STUDY; MALE; MEAN ARTERIAL PRESSURE; MULTICENTER STUDY; PRIORITY JOURNAL; PULMONARY ARTERY OCCLUSION PRESSURE; RANDOMIZED CONTROLLED TRIAL; TREATMENT RESPONSE;

ADULT; AGED; BLOOD PRESSURE; CARDIAC OUTPUT; FEMALE; HEART; HEART FAILURE; HEART RATE; HEART-ASSIST DEVICES; HUMANS; MALE; MIDDLE AGED; PULMONARY WEDGE PRESSURE; STROKE VOLUME; TREATMENT OUTCOME;

EID: 72249094732     PISSN: 10532498     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.healun.2009.10.005     Document Type: Article

References (15)

1. Greenberg B., Czerska B., Abraham W.T., et al. Rationale, design, and methods for a pivotal randomized clinical trial of continuous aortic flow augmentation in patients with exacerbation of heart failure: the MOMENTUM Trial. J Cardiac Fail 13 (2007) 715-721
2. Konstam M.A., Czerska B., Böhm M., et al. Continuous aortic flow augmentation: hemodynamic and renal responses to a novel percutaneous intervention in patients with decompensated heart failure. Circulation 112 (2005) 3107-3114
3. Haithcock B.E., Morita H., Fanous N.H., Suzuki G., and Sabbah H.N. Hemodynamic unloading of the failing left ventricle using an arterial-to-arterial extracorporeal flow circuit. Ann Thorac Surg 77 (2004) 158-163
4. Greenberg B., Czerska B., Delgado R.M., et al. Effects of continuous aortic flow augmentation in patients with exacerbation of heart failure inadequately responsive to medical therapy-results of the Multicenter Trial of the Orqis Medical Cancion System for the Enhanced Treatment of Heart Failure Unresponsive to Medical Therapy (MOMENTUM). Circulation 118 (2008) 1241-1249
5. Baicu C.F., Zile M.R., Aurigemma G.P., and Gaasch W.H. Left ventricular systolic performance, function, and contractility in patients with diastolic heart failure. Circulation 111 (2005) 2306-2312
6. Cohn J.N. Blood pressure and cardiac performance. Am J Med 55 (1973) 351-361
7. Sarnoff S.J., and Berglund E. Ventricular function-I. Starling's law of the heart studied by means of simultaneous right and left ventricular function curves in the dog. Circulation 9 (1954) 706-718
8. MacGregor D.C., Covell J.W., Mahler F., Dilley R.B., and Ross J. Relations between afterload, stroke volume, and descending limb of Starling's curve. Am J Physiol 227 (1974) 884-890
9. Ross J., and Braunwald E. The study of left ventricular function in man by increasing resistance to ventricular ejection with angiotensin. Circulation 29 (1964) 739-749
10. Rosamond W., Flegal K., Friday G., et al., American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Heart disease and stroke statistics: 2007 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation 115 (2007) e69-e171
11. Jain P., Massie B.M., Gattis W.A., Klein L., and Gheorghiade M. Current medical treatment for the exacerbation of chronic heart failure resulting in hospitalization. Am Heart J 145 (2003) S3-S17
12. Frazier O.H., Rose E.A., Oz M.C., et al., HeartMate Investigators. Multicenterclinical evaluation of the HeartMate vented electric left ventricular assist system in patients awaiting heart transplantation. J Thorac Cardiovasc Surg 122 (2001) 1186-1195
13. Rose E.A., Gelijns A.C., Moskowitz A.J., et al. Long-term use of a left ventricular assist device for end-stage heart failure. N Engl J Med 345 (2001) 1435-1443
14. Gharib M., and Beizaie M. Correlation between negative near-wall shear stress in human aorta and various stages of congestive heart failure. Ann Biomed Eng 3 (2003) 678-685
15. Lu X., and Kassab G.S. Nitric oxide is significantly reduced in ex-vivo porcine arteries during reverse flow because of increased superoxide production. J Physiol 561 (2004) 575-582