Optimization and validation of a high performance liquid chromatography method for rapid determination of sinafloxacin, a novel fluoroquinolone in rat plasma using a fused-core C18-silica column

Journal of Pharmaceutical and Biomedical Analysis

Volumn 51, Issue 4, 2010, Pages 889-893

  Wang, Shuowen ^a,b   Wen, Jun ^a,b   Cui, Lijun ^a,b   Zhang, Xiurong ^c   Wei, Hua ^a,b   Xie, Rui ^a,b   Feng, Bo ^c   Wu, Yutian ^a,b   Fan, Guorong ^a,b  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b SHANGHAI KEY LABORATORY FOR PHARMACEUTICAL METABOLITE RESEARCH   (China)

^c JILIN MEDICAL COLLEGE   (China)

Author keywords

96 well protein precipitation; Fluorescence detection; Fused core C18 silica column; High performance liquid chromatography; Sinafloxacin

Indexed keywords

6 FLUORO 1 METHYL 4 OXO 7 (1 PIPERAZINYL) 4H 1,3 THIAZETO[3,2 A]QUINOLINE 3 CARBOXYLIC ACID; ACETONITRILE; CIPROFLOXACIN; GATIFLOXACIN; LOMEFLOXACIN; NORFLOXACIN; OFLOXACIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT; SILICON DIOXIDE; SINAFLOXACIN; UNCLASSIFIED DRUG;

ACCURACY; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DETERMINATION; DRUG HALF LIFE; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MAXIMUM PLASMA CONCENTRATION; MEAN RESIDENCE TIME; NONHUMAN; PRECIPITATION; PRIORITY JOURNAL; PROCESS OPTIMIZATION; RAT; SENSITIVITY ANALYSIS; SINGLE DRUG DOSE; VALIDATION PROCESS;

ANIMALS; ANTI-BACTERIAL AGENTS; BUFFERS; CHEMICAL PRECIPITATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG STABILITY; FEMALE; FLUOROQUINOLONES; HYDROGEN-ION CONCENTRATION; INJECTIONS, INTRAVENOUS; MALE; RATS; RATS, SPRAGUE-DAWLEY; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SILICON DIOXIDE;

EID: 72149119460     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2009.09.046     Document Type: Article

References (21)

1. Li Z.Y., Lu G.C., Yuan B.J., Jiang H., Dai Y.M., She J.H., and Huang M. Chondrotoxicity of sinafloxacin in immature rats. Chin. J. New Drugs 15 (2006) 274-276
2. Lu G.C., She J.H., Jiang H., Li Z.Y., and Yuan B.J. Sixty-day repeated dose toxicity of sinafloxacin in rats and dogs. Food Chem. Toxicol. 46 (2008) 575-580
3. Jiang H., Lu G.C., Yuan B.J., Li Z.Y., and She J.H. Safety pharmacology study of KNT009. Pharm. Practic. 23 (2005) 266-269
4. Fei Y., Lu G.C., Fan G.R., Qi Y.P., Wu H.L., and Wu Y.T. Studies on interaction between sinafloxacin and bovine serum albumin as well as effect of the coexistent metal ions on the reaction. Guang Pu Xue Yu Guang Pu Fen Xi 28 (2008) 2609-2614
5. Y. Fei, G.C. Lu, G.R., Fan, Y.T. Wu, Spectroscopic studies on the binding of a new quinolone antibacterial agent: sinafloxacin to DNA, Anal. Sci. 25 (2009), in press.
6. Gritti F., and Guiochon G. Unusual behavior of the height equivalent to a theoretical plate of a new poroshell stationary phase at high temperatures. J. Chromatogr. A 1169 (2007) 125-138
7. Hsieh Y., Duncan C.J.G., and Brisson J.M. Fused-core silica column high-performance liquid chromatography/tandem mass spectrometric determination of rimonabant in mouse plasma. Anal. Chem. 79 (2007) 5668-5673
8. Cunliffe J.M., and Maloney T.D. Fused-core particle technology as an alternative to sub-2-μm particle to achieve high separation efficiency with low backpressure. J. Sep. Sci. 30 (2007) 3104-3109
9. 18-bonded silica materials. J. Chromatogr. A 1157 (2007) 289-303
10. DeStefano J.J., Langlois T.J., and Kirkland J.J. Characteristics of superficially-porous silica particles for fast HPLC: some performance comparisons with sub-2-μm particles. J. Chromatogr. Sci. 46 (2008) 254-260
11. Abia J.A., Mriziq K.S., and Guiochon G.A. Rapid heterogeneity of some analytical used in high-performance liquid chromatography. J. Chromatogr. A 1216 (2009) 3185-3191
12. Gritti F., and Guiochon G. Comparative study of the performance of columns packed with several new fine silica particles would the external roughness of the particles affect column properties. J. Chromatogr. A 1166 (2007) 30-46
13. Gritti F., and Guiochon G. Comparison between the loading capacities of column packed with partially and totally porous fine particles what is the effective surface area available for adsorption?. J. Chromatogr. A 1176 (2007) 107-122
14. McCalley D.V. Evaluation of the properties of a superficially porous silica stationary phase in hydrophilic interaction chromatography. J. Chromatogr. A 1193 (2008) 85-91
15. 3 antagonist in human plasma and urine using liquid chromatography-tandem mass spectrometry. J. Chromatogr. B 806 (2004) 167-175
16. Wen J., Wu Y.W., Zhang L.L., Qi Y.P., Fan G.R., Wu Y.T., and Li Z. High-throughput determination of fudosteine in human plasma by liquid chromatography-tandem mass spectrometry, following protein precipitation in the 96-well plate format. J. Chromatogr. B 867 (2008) 153-159
17. Stass H., and Dalhoff A. Determination of BAY 12-8039, a new 8-methoxyquinolone, in human body fluids by high-performance liquid chromatography with fluorescence detection using on-column focusing. J. Chromatogr. B 702 (1997) 163-174
18. Dalhoff A., and Strass H. Determination of moxifloxacin by HPLC and bioassay. Practicality and limitations. Drugs 58 (1999) 239-241
19. Cohen E., Maxwell R.J., and Donoghue D.J. Automated multi-residue isolation of fluoroquinolone antimicrobials from fortified and incurred chicken liver using on-line microdialysis and high-performance liquid chromatography with programmable fluorescence detection. J. Chromatogr. B 724 (1999) 137-145
20. Horie M., Ssito K., Nose N., and Nakazawa H. Simultaneous determination of eight quinolone antibacterials in meat and fish by high performance liquid chromatography. J. Food Hyg. Soc. Jpn. 36 (1995) 62-67
21. Samanidou V.F., Demetriou C.E., and Papadoyannis I.N. Direct determination of four fluoroquinolones, enoxacin, norfloxacin, ofloxacin, and ciprofloxacin, in pharmaceuticals and blood serum by HPLC. Anal. Bioanal. Chem. 375 (2003) 623-629