Development and validation of a sensitive LC-MS method for the determination of Promethazine hydrochloride in human plasma and urine

European Journal of Drug Metabolism and Pharmacokinetics

Volumn 34, Issue 3-4, 2009, Pages 177-184

  Liu, Ping ^a   Liang, Sun ^b   Wang, Ben Jie ^a   Guo, Rui Chen ^a  

^a SHANDONG UNIVERSITY   (China)

^b Shandong Traditional Chinese Medicine University College of Pharmacy   (China)

Author keywords

Compound tramadol hydrochloride injection; CTHI; Liquid chromatography mass spectrometry; Plasma; Promethazine; Urine

Indexed keywords

PROMETHAZINE;

ACCURACY; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG DETERMINATION; DRUG HALF LIFE; DRUG STRUCTURE; HUMAN; HUMAN EXPERIMENT; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MAXIMUM PLASMA CONCENTRATION; MEAN RESIDENCE TIME; NORMAL HUMAN; PLASMA; PLASMA CONCENTRATION-TIME CURVE; RELIABILITY; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; TIME TO MAXIMUM PLASMA CONCENTRATION; URINE; VALIDITY;

EID: 72149111395     PISSN: 03787966     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF03191171     Document Type: Article

References (18)

1. Tarkkila P., Torn K., Tuominen M., Lindgren L., (1995): J. Acta Anaesthesiol. Scand., 39. 983.
2. Scherl E.R., Wilson J.F., (1995): J. Headache. 35, 256.
3. Buzdar A.U., Esparza L., Natale R., Cody R., Calzone K., Benson A.B., Sheehan T., Berry W., (1994): Am. J. Clin. Oncol., 17, 417.
4. Terndrup T.E., Dire D.J., Madden C.M., Davis H., Cantor R.M., Gavula D.P., (1991): J. Ann Emerg. Med., 20, 31.
5. Conner J.T., Bellville J.W., Wender R., Wapner S., Dorey F.J., Katz R.L., (1977): J. Anesth Anaig., 56, 801.
6. Ron M., Menashe M., Hochner-Celnikier D., Palti Z., (1984): Eur. J. Obstet. Gynecol. Reprod. Biol., 18, 25.
7. Lackner J.R., Graybiel A., (1994) : J. Clin Pharmacol., 34, 644.
8. Campbell M., Bateman D.N., (1992): J. Clin Pharmacokinet., 23, 147.
9. Stavchansky S., Wallace J.E., Geary R., Hecht G., Robb C.A., Wu P., (1987): J. Pharm Sci..76, 441.
10. Ponder G.W., Stewart J.T., (1995): J. Pharm. Biomed. Anal., 13, 1161.
11. Zaman R., Honigberg I.L., Francisco G.E., Kotzan J.A., Stewart J.T., Brown W.J., Shah V.P., Pelsor F.R., (1986): J. Biopharm Drug Dispos., 7, 281..
12. Schwinghammer T.L., Juhl R.P., Dittert L.W., Melethil S.K., Kroboth F.J., Chung V.S., (1984): J. Biopharm. Drug Dispos., 5, 185.
13. Fox A.R , McLoughlin D.A., (1993): J. Chromatogr., 631, 255.
14. Wallace J.E., Shimek E.L,Jr., Ilarris S.C., Stavchansky S., (1991): J. Clin. Chem., 27, 253.
15. Tompsett S.L., (1968): J. Acta Pharmacol.Toxicol., 26, 298.
16. Martin E.A., (1966): Can. J. Chem., 44, 1783.
17. Vanapalli S.R., Kambhampati S.P., Putcha L., Bourne D.W., (2001): J. Chromatogr. Sci.. 39, 70.
18. Guidance for industry, Bioanalytical Method Validation, US Department of Health and Human Services, May 2001.