Direct detection of Δ9-tetrahydrocannabinol in saliva using a novel homogeneous competitive immunoassay with fluorescence quenching

Analytica Chimica Acta

Volumn 658, Issue 2, 2010, Pages 187-192

  Tan, Chongxiao ^a   Gajovic Eichelmann, Nenad ^a   Stöcklein, Walter F M ^a   Polzius, Rainer ^b   Bier, Frank F ^a  

^a FRAUNHOFER INSTITUTE FOR BIOMEDICAL ENGINEERING   (Germany)

^b Architecture of Drägerwerk AG and Co KGaA   (Germany)

Author keywords

9 Tetrahydrocannabinol; Drug test; Fluorescence quenching; Fluorescence resonance energy transfer; Homogeneous immunoassay; Saliva

Indexed keywords

ACTIVE COMPONENTS; AQUEOUS SAMPLES; BOVINE SERUM ALBUMINS; COMPETITIVE IMMUNOASSAY; CONCENTRATION OF; DETECTION LIMITS; DIRECT DETECTION; DRUG TESTS; FLUORESCENCE QUENCHING; FLUORESCENCE RESONANCE ENERGY TRANSFER; QUENCHING EFFECT; TEST DURATION;

ANTIBODIES; ANTIGENS; BINDING ENERGY; BINDING SITES; BODY FLUIDS; ENERGY TRANSFER; IMMUNOLOGY; QUENCHING; RESONANCE;

FLUORESCENCE;

BOVINE SERUM ALBUMIN; DRONABINOL; FLUORESCENT DYE; ANTIBODY; TETRAHYDROCANNABINOL;

ADULT; ANTIBODY LABELING; AQUEOUS SOLUTION; ARTICLE; BINDING COMPETITION; BINDING SITE; CANNABIS ADDICTION; COMPLEX FORMATION; CONCENTRATION (PARAMETERS); CONJUGATION; CONTROLLED STUDY; FEMALE; FLUORESCENCE ANALYSIS; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMAN; IMMUNOASSAY; MALE; PRIORITY JOURNAL; SALIVA ANALYSIS; SENSITIVITY AND SPECIFICITY; CHEMISTRY; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOLOGY; METABOLISM; METHODOLOGY; SALIVA; STATISTICAL PARAMETERS;

BOVINAE; CANNABIS;

ADULT; ANTIBODIES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLUORESCENCE RESONANCE ENERGY TRANSFER; FLUORESCENT DYES; HUMANS; LIMIT OF DETECTION; MALE; SALIVA; TETRAHYDROCANNABINOL;

EID: 72049133415     PISSN: 00032670     EISSN: 18734324     Source Type: Journal    
DOI: 10.1016/j.aca.2009.11.012     Document Type: Article

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