Obstructive Sleep Apnea as a Risk Factor for Type 2 Diabetes

American Journal of Medicine

Volumn 122, Issue 12, 2009, Pages 1122-1127

  Botros, Nader ^a   Concato, John ^a,b   Mohsenin, Vahid ^a   Selim, Bernardo ^a   Doctor, Kervin ^b   Yaggi, Henry Klar ^a,b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VA CONNECTICUT HEALTHCARE SYSTEM   (United States)

Author keywords

Sleep apnea syndrome; Type 2 diabetes mellitus

Indexed keywords

GLUCOSE;

ADULT; AGED; APNEA HYPOPNEA INDEX; ARTICLE; COHORT ANALYSIS; DISEASE SEVERITY; FEMALE; FUNCTION TEST; GLUCOSE BLOOD LEVEL; GLUCOSE INTOLERANCE; HUMAN; INSULIN RESISTANCE; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PATIENT COMPLIANCE; POLYSOMNOGRAPHY; POSITIVE END EXPIRATORY PRESSURE; PRIORITY JOURNAL; RISK FACTOR; SLEEP APNEA SYNDROME; SLEEP DISORDERED BREATHING; TREATMENT OUTCOME;

AGED; COHORT STUDIES; CONTINUOUS POSITIVE AIRWAY PRESSURE; DIABETES MELLITUS, TYPE 2; FEMALE; HUMANS; HYPERTENSION; MALE; MIDDLE AGED; OBESITY; POLYSOMNOGRAPHY; RISK FACTORS; SEVERITY OF ILLNESS INDEX; SLEEP APNEA, OBSTRUCTIVE;

EID: 72049129932     PISSN: 00029343     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.amjmed.2009.04.026     Document Type: Article

References (45)

1. American Diabetes Association. Diagnosis and classification of diabetes mellitus. Diabetes Care 28 Suppl 1 (2005) S37-S42
2. Young T., Palta M., Dempsey J., et al. The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med 328 (1993) 1230-1235
3. Drager L.F., Bortolotto L.A., Figueiredo A.C., et al. Effects of continuous positive airway pressure on early signs of atherosclerosis in obstructive sleep apnea. Am J Respir Crit Care Med 176 (2007) 706-712
4. Marin J.M., Carrizo S.J., Vicente E., and Agusti A.G. Long-term cardiovascular outcomes in men with obstructive sleep apnoea-hypopnoea with or without treatment with continuous positive airway pressure: an observational study. Lancet 365 9464 (2005) 1046-1053
5. Peppard P., Young T., Palta M., and Skatrud J.B. Prospective study of the association between sleep-disordered breathing and hypertension. N Engl J Med 342 (2000) 1378-1384
6. Yaggi H., Concato J., Kernan W., et al. Obstructive sleep apnea as a risk factor for stroke and death. N Engl J Med 353 (2005) 2034-2041
7. Young T., Finn L., Peppard P., et al. Sleep disordered breathing and mortality: eighteen-year follow-up of the Wisconsin sleep cohort. Sleep 31 (2008) 1071-1078
8. Punjabi N.M., Shahar E., Redline S., et al. Sleep-disordered breathing, glucose intolerance, and insulin resistance: the Sleep Heart Health Study. Am J Epidemiol 160 (2004) 521-530
9. Yaggi H.K., Araujo A.B., and McKinlay J.B. Sleep duration as a risk factor for the development of type 2 diabetes. Diabetes Care 29 (2006) 657-661
10. Coughlin S.R., Mawdsley L., Mugarza J.A., et al. Obstructive sleep apnoea is independently associated with an increased prevalence of metabolic syndrome. Eur Heart J 25 (2004) 735-741
11. Ip M.S., Lam B., Ng M.M., et al. Obstructive sleep apnea is independently associated with insulin resistance. Am J Respir Crit Care Med 165 (2002) 670-676
12. Meslier N., Gagnadoux F., Giraud P., et al. Impaired glucose-insulin metabolism in males with obstructive sleep apnoea syndrome. Eur Respir J 22 (2003) 156-160
13. Punjabi N.M., Sorkin J.D., Katzel L.I., et al. Sleep-disordered breathing and insulin resistance in middle-aged and overweight men. Am J Respir Crit Care Med 165 (2002) 677-682
14. Resnick H.E., Redline S., Shahar E., et al. Diabetes and sleep disturbances: findings from the Sleep Heart Health Study. Diabetes Care 26 (2003) 702-709
15. Tiihonen M., Partinen M., and Narvanen S. The severity of obstructive sleep apnoea is associated with insulin resistance. J Sleep Res 2 (1993) 56-61
16. Johns M.W. A new method for measuring daytime sleepiness: the Epworth Sleepiness Scale. Sleep 14 (1991) 540-545
17. Sleep-related breathing disorders in adults: recommendations for syndrome definition and measurement techniques in clinical research. The Report of an American Academy of Sleep Medicine Task Force. Sleep 22 (1999) 667-689
18. Meoli A.L., Casey K.R., Clark R.W., et al. Hypopnea in sleep-disordered breathing in adults. Sleep 24 (2001) 469-470
19. Rechtschaffen A., and Kales A. A Manual of Standardized Terminology, Techniques and scoring System for Sleep Stages of Human Subjects (1968), UCLA Brain Information Service/Brain Research Institute, Los Angeles, CA
20. American Diabetes Association. Diagnosis and classification of diabetes mellitus. Diabetes Care 31 Suppl 1 (2008) S55-S60
21. Loube D.I., Gay P.C., Strohl K.P., et al. Indications for positive airway pressure treatment of adult obstructive sleep apnea patients: a consensus statement. Chest 115 (1999) 863-866
22. Schoenfeld P. Sample-size formula for the proportional-hazards regression model. Biometrics 39 (1983) 499-503
23. Coughlin S.R., Mawdsley L., Mugarza J.A., et al. Cardiovascular and metabolic effects of CPAP in obese males with OSA. Eur Respir J 29 (2007) 720-727
24. Reichmuth K.J., Austin D., Skatrud J.B., and Young T. Association of sleep apnea and type II diabetes: a population-based study. Am J Respir Crit Care Med 172 (2005) 1590-1595
25. West S.D., Nicoll D.J., Wallace T.M., et al. Effect of CPAP on insulin resistance and HbA1c in men with obstructive sleep apnoea and type 2 diabetes. Thorax 62 (2007) 969-974
26. West S. Prevalence of obstructive sleep apnea in men with type 2 diabetes. Thorax 61 (2006) 945-950
27. Ficker J.H., Dertinger S.H., Siegfried W., et al. Obstructive sleep apnoea and diabetes mellitus: the role of cardiovascular autonomic neuropathy. Eur Respir J 11 (1998) 14-19
28. Bottini P. Sleep-disordered breathing in nonobese diabetic subjects with autonomic neuropathy. Eur Respir J 22 (2003) 654-660
29. Al-Delaimy W.K., Manson J.E., Willett W.C., et al. Snoring as a risk factor for type II diabetes mellitus: a prospective study. Am J Epidemiol 155 (2002) 387-393
30. Elmasry A., Janson C., Lindberg E., et al. The role of habitual snoring and obesity in the development of diabetes: a 10-year follow-up study in a male population. J Intern Med 248 (2000) 13-20
31. Marshall N.S., Wong K.K., Phillips C.L., et al. Is sleep apnea an independent risk factor for prevalent and incident diabetes in the Busselton Health Study?. J Clin Sleep Med 5 (2009) 15-20
32. Redline S., Storfer-Isser A., Rosen C.L., et al. Association between metabolic syndrome and sleep-disordered breathing in adolescents. Am J Respir Crit Care Med 176 (2007) 401-408
33. Sulit L., Storfer-Isser A., Kirchner H.L., and Redline S. Differences in polysomnography predictors for hypertension and impaired glucose tolerance. Sleep 29 (2006) 777-783
34. Polotsky V.Y., Li J., Punjabi N.M., et al. Intermittent hypoxia increases insulin resistance in genetically obese mice. J Physiol 552 Pt 1 (2003) 253-264
35. Yamauchi M., Nakano H., Maekawa J., et al. Oxidative stress in obstructive sleep apnea. Chest 127 (2005) 1674-1679
36. Punjabi N. Disorders of glucose metabolism in sleep apnea. J Appl Physiol 99 (2005) 1998-2007
37. Chasens E.R., Weaver T.E., and Umlauf M.G. Insulin resistance and obstructive sleep apnea: is increased sympathetic stimulation the link?. Biol Res Nurs 5 (2003) 87-96
38. Somers V.K., Mark A.L., and Abboud F.M. Sympathetic activation by hypoxia and hypercapnia-implications for sleep apnea. Clin Exp Hypertens A 10 Suppl 1 (1988) 413-422
39. Somers V.K., Dyken M.E., Clary M.P., and Abboud F.M. Sympathetic neural mechanisms in obstructive sleep apnea. J Clin Invest 96 (1995) 1897-1904
40. Babu A.R., Herdegen J., Fogelfeld L., et al. Type 2 diabetes, glycemic control, and continuous positive airway pressure in obstructive sleep apnea. Arch Intern Med 165 (2005) 447-452
41. Harsch I.A., Schahin S.P., Bruckner K., et al. The effect of continuous positive airway pressure treatment on insulin sensitivity in patients with obstructive sleep apnoea syndrome and type 2 diabetes. Respiration 71 (2004) 252-259
42. Harsch I.A., Schahin S.P., Radespiel-Troger M., et al. Continuous positive airway pressure treatment rapidly improves insulin sensitivity in patients with obstructive sleep apnea syndrome. Am J Respir Crit Care Med 169 (2004) 156-162
43. FA. Ribeiro-Filho F.F., Azjen S., Zanella M.T., and Ferreira S.R. Methods of estimation of visceral fat: Advantages of ultrasonography. Obes Rev 11 (2003) 1488-1494
44. BW. Rossner S., Hiltbrandt E., Hinson W., et al. Adipose tissue determinations in cadavers. A comparison between cross-sectional planimetry and computed tomography. Int J Obes 14 (1990) 893-902
45. Hirshkowitz M., Littner M., Kuna S., et al. Sleep-related Breathing Disorders: Sourcebook. 2nd edition (2003), Healthcare Analysis & Information Group (HAIG), VHA, Milwaukee, WI