Regional Lung Density Changes After Radiation Therapy for Tumors in and Around Thorax

International Journal of Radiation Oncology Biology Physics

Volumn 76, Issue 1, 2010, Pages 116-122

  Ma, Jinli ^a,b   Zhang, Junan ^a   Zhou, Sumin ^a   Hubbs, Jessica L ^c   Foltz, Rodney J ^a   Hollis, Donna R ^a   Light, Kim L ^a   Wong, Terence Z ^a   Kelsey, Christopher R ^a   Marks, Lawrence B ^c  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b FUDAN UNIVERSITY SHANGHAI CANCER CENTER   (China)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Computed tomography; Dose response curve; Lung density

Indexed keywords

COMPUTED TOMOGRAPHY; COMPUTED TOMOGRAPHY SCAN; COVARIATES; DENSITY CHANGE; DOSE-DEPENDENT; DOSE-RESPONSE CURVES; FOLLOW-UP CT SCAN; FOLLOW-UP INTERVALS; LINEAR-QUADRATIC MODELS; LUNG INJURY; PLANNING TOOLS; RADIATION THERAPY; UNIVARIATE ANALYSIS;

COMPUTERIZED TOMOGRAPHY; IMAGE FUSION; RADIOTHERAPY; THREE DIMENSIONAL;

BIOLOGICAL ORGANS;

ADULT; AGED; ARTICLE; BREAST CANCER; CANCER RADIOTHERAPY; COMPUTER ASSISTED TOMOGRAPHY; ESOPHAGUS CANCER; FEMALE; FOLLOW UP; GROUPS BY AGE; HUMAN; KIDNEY CANCER; LUNG CANCER; LUNG INJURY; LUNG VOLUME; LYMPHOMA; MAJOR CLINICAL STUDY; MALE; MELANOMA; PRIORITY JOURNAL; RADIATION DOSE; RADIATION INJURY; THREE DIMENSIONAL IMAGING; THYMUS CANCER; TREATMENT OUTCOME; TREATMENT PLANNING;

ADULT; AGED; AGED, 80 AND OVER; ALGORITHMS; ANALYSIS OF VARIANCE; BREAST NEOPLASMS; DOSE-RESPONSE RELATIONSHIP, RADIATION; FEMALE; FOLLOW-UP STUDIES; HUMANS; LINEAR MODELS; LUNG; LUNG NEOPLASMS; LYMPHOMA; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; RADIATION INJURIES; RADIOTHERAPY PLANNING, COMPUTER-ASSISTED; TOMOGRAPHY, X-RAY COMPUTED; YOUNG ADULT;

EID: 72049126080     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2009.01.025     Document Type: Article

References (26)

1. Marks L.B., Fan M., Clough R., et al. Radiation-induced pulmonary injury: Symptomatic versus subclinical endpoints. Int J Radiat Biol 76 (2000) 469-475
2. Kahan Z., Csenki M., Varga Z., et al. The risk of early and late lung sequelae after conformal radiotherapy in breast cancer patients. Int J Radiat Oncol Biol Phys 68 (2007) 673-681
3. Yom S.S., Liao Z., Liu H.H., et al. Initial evaluation of treatment-related pneumonitis in advanced-stage non-small-cell lung cancer patients treated with concurrent chemotherapy and intensity-modulated radiotherapy. Int J Radiat Oncol Biol Phys 68 (2007) 94-102
4. Boersma L.J., Damen E.M., de Boer R.W., et al. A new method to determine dose-effect relations for local lung-function changes using correlated SPECT and CT data. Radiother Oncol 29 (1993) 110-116
5. Mah K., and Van Dyk J. Quantitative measurement of changes in human lung density following irradiation. Radiother Oncol 11 (1988) 169-179
6. Lind P.A., Svane G., Gagliardi G., et al. Abnormalities by pulmonary regions studied with computer tomography following local or local-regional radiotherapy for breast cancer. Int J Radiat Oncol Biol Phys 43 (1999) 489-496
7. Evans E.S., Hahn C.A., Kocak Z., et al. The role of functional imaging in the diagnosis and management of late normal tissue injury. Semin Radiat Oncol 17 (2007) 72-80
8. Boersma L.J., Damen E.M., de Boer R.W., et al. Dose-effect relations for local functional and structural changes of the lung after irradiation for malignant lymphoma. Radiother Oncol 32 (1994) 201-209
9. Skoczylas J.Z., Bentzen S.M., Overgaard M., et al. Time course of radiological lung density changes after postmastectomy radiotherapy. Acta Oncol 39 (2000) 181-187
10. Wennberg B., Gagliardi G., Sundbom L., et al. Early response of lung in breast cancer irradiation: Radiologic density changes measured by CT and symptomatic radiation pneumonitis. Int J Radiat Oncol Biol Phys 52 (2002) 1196-1206
11. Garipagaoglu M., Munley M.T., Hollis D., et al. The effect of patient-specific factors on radiation-induced regional lung injury. Int J Radiat Oncol Biol Phys 45 (1999) 331-338
12. Marks L.B., Munley M.T., Spencer D.P., et al. Quantification of radiation-induced regional lung injury with perfusion imaging. Int J Radiat Oncol Biol Phys 38 (1997) 399-409
13. Levinson B., Marks L.B., Munley M.T., et al. Regional dose response to pulmonary irradiation using a manual method. Radiother Oncol 48 (1998) 53-60
14. Boersma L.J., Damen E.M., de Boer R.W., et al. Estimation of overall pulmonary function after irradiation using dose-effect relations for local functional injury. Radiother Oncol 36 (1995) 15-23
15. Theuws J.C., Kwa S.L., Wagenaar A.C., et al. Dose-effect relations for early local pulmonary injury after irradiation for malignant lymphoma and breast cancer. Radiother Oncol 48 (1998) 33-43
16. Mah K., Van Dyk J., Keane T., et al. Acute radiation-induced pulmonary damage: A clinical study on the response to fractionated radiation therapy. Int J Radiat Oncol Biol Phys 13 (1987) 179-188
17. Blom-Goldman U., Svane G., Wennberg B., et al. Quantitative assessment of lung density changes after 3-D radiotherapy for breast cancer. Acta Oncol 46 (2007) 187-193
18. Mah K., Keane T.J., Van Dyk J., et al. Quantitative effect of combined chemotherapy and fractionated radiotherapy on the incidence of radiation-induced lung damage: A prospective clinical study. Int J Radiat Oncol Biol Phys 28 (1994) 563-574
19. Marks L.B., Munley M.T., Bentel G.C., et al. Physical and biological predictors of changes in whole-lung function following thoracic irradiation. Int J Radiat Oncol Biol Phys 39 (1997) 563-570
20. Fan M., Marks L.B., Hollis D., et al. Can we predict radiation-induced changes in pulmonary function based on the sum of predicted regional dysfunction?. J Clin Oncol 19 (2001) 543-550
21. Woel R.T., Munley M.T., Hollis D., et al. The time course of radiation therapy-induced reductions in regional perfusion: A prospective study with >5 years of follow-up. Int J Radiat Oncol Biol Phys 52 (2002) 58-67
22. Miller K.L., Zhou S.M., Barrier Jr. R.C., et al. Long-term changes in pulmonary function tests after definitive radiotherapy for lung cancer. Int J Radiat Oncol Biol Phys 56 (2003) 611-615
23. Fan M., Marks L.B., Lind P., et al. Relating radiation-induced regional lung injury to changes in pulmonary function tests. Int J Radiat Oncol Biol Phys 51 (2001) 311-317
24. Theuws J.C., Seppenwoolde Y., Kwa S.L., et al. Changes in local pulmonary injury up to 48 months after irradiation for lymphoma and breast cancer. Int J Radiat Oncol Biol Phys 47 (2000) 1201-1208
25. Kocak Z., Yu X., Zhou S.M., et al. The impact of pre-radiotherapy surgery on radiation-induced lung injury. Clin Oncol (R Coll Radiol) 17 (2005) 210-216
26. Ma J., Zhang J., Zhou S., et al. Is the development of symptomatic radiation pneumonitis associated with an inherent increased sensitivity of lung to radiation-induced injury?. [Abstract]. Int J Radiat Oncol Biol Phys 69 (2007) S155-S156