Longitudinal changes in plasma Transforming growth factor beta-1 and post-burn scarring in children

Burns

Volumn 36, Issue 1, 2010, Pages 89-96

  Rorison, Patricia ^a   Thomlinson, Alison ^b   Hassan, Zahid ^b,c   Roberts, Stephen A ^b   Ferguson, Mark W J ^b   Shah, Mamta ^b,d  

^a BIRMINGHAM CHILDREN S HOSPITAL   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c WHISTON HOSPITAL   (United Kingdom)

^d MANCHESTER UNIVERSITY NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

Post burn scarring; Transforming growth factor beta1

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA1;

ARTICLE; BURN; BURN PATIENT; CHILD; CHILDHOOD; CLINICAL ARTICLE; CONTROLLED STUDY; ESTHETICS; FEMALE; HUMAN; HYPERTROPHIC SCAR; LONGITUDINAL STUDY; MALE; MENTAL DISEASE; MORBIDITY; PEDIATRICS; PRESCHOOL CHILD; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; RISK ASSESSMENT; THERMAL INJURY; WOUND HEALING;

BIOLOGICAL MARKERS; BURNS; CHILD; CHILD, PRESCHOOL; CICATRIX, HYPERTROPHIC; FEMALE; HUMANS; INFANT; LONGITUDINAL STUDIES; MALE; TIME FACTORS; TRANSFORMING GROWTH FACTOR BETA1; WOUND HEALING;

EID: 72049112288     PISSN: 03054179     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.burns.2009.03.008     Document Type: Article

References (17)

1. Deitch E.A., Wheelahan T.M., Rose M.P., Clothier J., and Cotter J. Hypertrophic burn scars: analysis of variables. J Trauma 23 (1983) 895
2. Cubison T.C.S., Pape S.A., and Parkhouse N. Evidence for the link between healing time and the development of hypertrophic scar (HTS) in paediatric burns due to scalds. Burns 32 (2006) 992-999
3. McDonald W.S., and Deitch E.A. Hypertrophic skin grafts in burned patients: a prospective analysis of variables. J Trauma 27 (1987) 147
4. Tredget E.E., Nedelaec B., Scott P.G., and Ghahary A. Hypertrophic scars, keloids and contractures: The cellular and molecular basis of therapy. Surg Clin North Am 77 (1997) 701
5. Wang J.F., Jiao H., Stewart T.L., Shankowsky, Scott P.G., and Tredget E.E. Increased TGFβ-producing CD4+ T lymphocytes in post-burn patients and their potential interaction with dermal fibroblasts in hypertrophic scarring. Wound Repair Regeneration 15 (2007) 530-535
6. Shah M., Foreman D.M., and Ferguson M.W.J. Neutralisation of TGF beta1 and TGF beta2, or exogenous addition of TGF beta3, to cutaneous rat wounds reduces scarring. J Cell Sci 108 (1995) 985
7. Rameshwar P., Chang V.T., Thacker U.F., and Gascon P. Systemic transforming growth factor-beta in patients with bone marrow fibrosis-pathophysiological implications. Am J Hematol 59 (1998) 133
8. Tredget E.E., Shankowsky H.A., Pannu R., et al. Transforming growth factor beta in thermally injured patients with hypertrophic scars: effects of interferon α2b. Plast Reconstr Surg 102 (1998) 1317
9. Sullivan T., Smith J., Kermode J., McIver E., and Courtemanche D.J. Rating the burn scar. J Burn Care Rehabil 11 (1990) 256
10. Wakefield L.M., Letterio J.J., Chen T., et al. Transforming growth factor beta1 circulates in normal human plasma and is unchanged in advanced metastatic breast cancer. Clin Cancer Res 1 (1995) 129
11. Shah M., Revis Jr. D., Herrick S., et al. Role of elevated plasma TGF beta1 levels in wound healing. Am J Pathol 154 (1999) 1115
12. Yang L., Scott P.G., Giuffre J., Shankowsky H.A., Ghahary A., and Tredget E.E. Peripheral blood fibrocytes from burn patients: identification and quantification of fibrocytes in adherent cells cultured from peripheral blood mononuclear cells. Lab Invest 82 (2002) 1183
13. Nishimura T., Nishiura T., deSerres S., Nakagawa T., Brenner D.A., and Meyer A.A. Impact of burn injury on hepatic TGF beta1 expression and plasma TGF beta1 levels. J Trauma 48 (2000) 39
14. Varedi M., Jeschke M.G., Englander E.W., Herndon D.N., and Barrow R.E. Serum TGF beta in thermally injured rats. Shock 16 (2001) 380
15. Aoki K., Aikawa N., Sekine K., et al. Elevation of plasma free PAI-1 levels as an integrated endothelial response to severe burns. Burns 27 (2001) 569
16. Proulx F., Litalien C., Turgeon J.P., Mariscalco M.M., and Seidman E. Circulating levels of Transforming growth factor beta1 and lymphokines among children with hemolytic uremic syndrome. Am J Kidney Dis 35 (2000) 29
17. Anscher M.S., Peters W.P., Reisenbichler H., Petros W.P., and Jirtle R.L. Transforming growth factor beta as a predictor of liver and lung fibrosis after autologous bone marrow transplantation for advanced breast cancer. N Engl J Med 328 (1993) 1592