Convergent functional genomics: What we have learned and can learn about genes, pathways, and mechanisms

Neuropsychopharmacology

Volumn 35, Issue 1, 2010, Pages 355-356

  Niculescu, Alexander B ^a   Le Niculescu, Helen ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BAYES THEOREM; BIPOLAR DISORDER; FUNCTIONAL GENOMICS; GENE; GENETIC HETEROGENEITY; GENETIC MARKER; GENETIC POLYMORPHISM; HUMAN; NEUROBIOLOGY; NONHUMAN; PRIORITY JOURNAL; SCHIZOPHRENIA; SHORT SURVEY;

ANIMALS; BAYES THEOREM; BIOLOGICAL MARKERS; BIPOLAR DISORDER; DATABASES, GENETIC; GENETIC PREDISPOSITION TO DISEASE; GENOMICS; HUMANS; MENTAL DISORDERS; MODELS, GENETIC; SCHIZOPHRENIA;

EID: 72049106429     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1038/npp.2009.107     Document Type: Short Survey

References (6)

1. Le-Niculescu H, Balaraman Y, Patel S, Tan J, Sidhu K, Jerome RE et al (2007). Towards understanding the schizophrenia code: an expanded convergent functional genomics approach. Am J Med Genet B Neuropsychiatr Genet 144B: 129-158. (Pubitemid 46606639)
2. Le-Niculescu H, Kurian SM, Yehyawi N, Dike C, Patel SD, Edenberg HJ et al (2009a). Identifying blood biomarkers for mood disorders using convergent functional genomics. Mol Psychiatry 14: 156-174.
3. Le-Niculescu H, Patel SD, Bhat M, Kuczenski R, Faraone SV, Tsuang MT et al (2009b). Convergent functional genomics of genome-wide association data for bipolar disorder: comprehensive identification of candidate genes, pathways and mechanisms. Am J Med Genet B Neuropsychiatr Genet 150B: 155-181.
4. Niculescu A, Segal D, Kuczenski R, Barrett T, Hauger R, Kelsoe J (2000). Identifying a series of candidate genes for mania and psychosis: a convergent functional genomics approach. Physiol Genomics 4: 83-91.
5. Niculescu AB, Lulow LL, Ogden CA, Le-Niculescu H, Salomon DR, Schork NJ et al (2006). PhenoChip-ping of psychotic disorders: a novel approach for deconstructing and quantitating psychiatric phe-notypes. Am J Med Genet B Neuropsychiatr Genet 141: 653-662.
6. Ogden CA, Rich ME, Schork NJ, Paulus MP, Geyer MA, Lohr JB et al (2004). Candidate genes, pathways and mechanisms for bipolar (manic-depressive) and related disorders: an expanded convergent functional genomics approach. Mol Psychiatry 9: 1007-1029.