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66349130961
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Gudmundsson K.S., Sebahar P.R., Richardson L., Catalano J.G., Boggs S.D., Spaltenstein A., Sethna P.B., Brown K.W., Harvey R., and Romines K.R. Bioorg. Med. Chem. Lett. 19 (2009) 3489
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Gudmundsson, K.S.1
Sebahar, P.R.2
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Boggs, S.D.5
Spaltenstein, A.6
Sethna, P.B.7
Brown, K.W.8
Harvey, R.9
Romines, K.R.10
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10
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67649965554
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Gudmundsson K.S., Boggs S.D., Sebahar P.R., Richardson L., Spaltenstein A., Golden P., Sethna P.B., Brown K.W., Moniri K., Harvey R., and Romines K.R. Bioorg. Med. Chem. Lett. 19 (2009) 4110
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Spaltenstein, A.5
Golden, P.6
Sethna, P.B.7
Brown, K.W.8
Moniri, K.9
Harvey, R.10
Romines, K.R.11
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12
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72049116642
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For a description of the assay see: Boggs, S.; Catalano, J.; Gudmundsson, K. S.; Richardson, L. D.; Sebahar, P. R. WO 2005/023245.
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For a description of the assay see: Boggs, S.; Catalano, J.; Gudmundsson, K. S.; Richardson, L. D.; Sebahar, P. R. WO 2005/023245.
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13
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62049083306
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Harvey R., Brown K., Zhang Q., Gartland M., Walton L., Talarico C., Lawrence W., Selleseth D., Coffield N., Leary J., Moniri K., Singer S., Strum J., Gudmundsson K., Biron K., Romines K.R., and Sethna P. Antiviral Res. 82 (2009) 1
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Harvey, R.1
Brown, K.2
Zhang, Q.3
Gartland, M.4
Walton, L.5
Talarico, C.6
Lawrence, W.7
Selleseth, D.8
Coffield, N.9
Leary, J.10
Moniri, K.11
Singer, S.12
Strum, J.13
Gudmundsson, K.14
Biron, K.15
Romines, K.R.16
Sethna, P.17
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14
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4243241249
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For previous syntheses of tetrahydro-β-carbolines see:
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For previous syntheses of tetrahydro-β-carbolines see:. Cox E.D., and Cook J.M. Chem. Rev. 95 (1995) 1797
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Cook, J.M.2
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For Pictet-Spengler reaction with glyoxylic acid see:
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For Pictet-Spengler reaction with glyoxylic acid see:. Ho B.T., and Walker K.E. Org. Synth. 51 (1971) 136
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Ho, B.T.1
Walker, K.E.2
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16
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72049124381
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note
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2, flow rate 2 mL/min at 1500 psi, 27 °C.
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17
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0030580848
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-1. The gaussian 98 Suite of computational programs was used to calculate model VCD spectra. Stereochemical assignments made by comparing calculated and measured spectra. For references:
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-1. The gaussian 98 Suite of computational programs was used to calculate model VCD spectra. Stereochemical assignments made by comparing calculated and measured spectra. For references:. Chesseman J.R., Frisch M.J., Devlin F.J., and Stephens P.J. Chem. Phys. Lett. 252 (1996) 211
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Chesseman, J.R.1
Frisch, M.J.2
Devlin, F.J.3
Stephens, P.J.4
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