Two novel neo-clerodane diterpenoids from Scutellaria barbata

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 1, 2010, Pages 288-290

  Lee, Hanna ^a   Kim, YuJin ^a   Choi, Inho ^a   Min, Byung Sun ^b   Shim, Sang Hee ^a  

^a Yeungnam University   (South Korea)

^b Catholic University of Daegu   (South Korea)

Author keywords

Cytotoxicity; Isolation; Neo clerodane; Structure determination

Indexed keywords

ANTINEOPLASTIC AGENT; BARBATELLARINE A; BARBATELLARINE B; DITERPENOID; DOXORUBICIN; SCUTEBARBATINE F; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN HL 60; CELL STRAIN MCF 7; CONTROLLED STUDY; CYTOTOXICITY; DRUG ISOLATION; DRUG STRUCTURE; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE; SCUTELLARIA; SCUTELLARIA BARBATA; STEREOCHEMISTRY;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL LINE, TUMOR; DITERPENES; DITERPENES, CLERODANE; DRUG SCREENING ASSAYS, ANTITUMOR; HL-60 CELLS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; SCUTELLARIA;

SCUTELLARIA BARBATA;

EID: 72049087199     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.10.116     Document Type: Article

References (14)

1. Kizu H., Imoto Y., Tomimori T., Kikuchi T., Kadota S., and Tsubono K. Chem. Pharm. Bull. 45 (1997) 152
2. Dai S.-J., Liang D.-D., Ren Y., Liu K., and Shen L. Chem. Pharm. Bull. 56 (2008) 207
3. Dai S.-J., Tao J.-Y., Liu K., Jiang Y.-T., and Shen L. Phytochemistry 67 (2006) 1326
4. Dai S.-J., Wang G.-F., Chen M., Liu K., and Shen L. Chem. Pharm. Bull. 55 (2007) 1218
5. Dai S.-J., Chen M., Liu K., Jiang Y.-T., and Shen L. Chem. Pharm. Bull. 54 (2006) 869
6. Yu J., Lei J., Yu H., Cai X., and Zou G. Phytochemistry 65 (2004) 881
7. Wang Y., Xue X., Xiao Y., Zhang F., Xu Q., and Liang X. J. Sep. Sci. 31 (2008) 1669
8. Bruni M., Piozzi F., and Rosselli S. Nat. Prod. Rep. 19 (2002) 357
9. Dai S.-J., Peng W.-B., Shen L., Zhang D.-W., and Ren Y.J. Asian Nat. Prod. Res. 11 (2009) 451
10. Kizu H., Sugita N., and Tomimori T. Chem. Pharm. Bull. 46 (1998) 988
11. R = 22.3 min).
12. 10+Na, 593.2363.
13. 9+H, 618.2703.
14. Mosmann T. J. Immunol. Methods 65 (1983) 55