메뉴 건너뛰기




Volumn 161, Issue 5, 2009, Pages 1130-1135

Para-phenylenediamine and allergic sensitization: Risk modification by N-acetyltransferase 1 and 2 genotypes

Author keywords

Allergic contact dermatitis; Metabolism; N acetyltransferases 1 and 2; Para phenylenediamine; Polymorphism; T cell stimulation

Indexed keywords

ACYLTRANSFERASE; ARYLAMINE ACETYLTRANSFERASE; PHENYLENEDIAMINE;

EID: 71949124981     PISSN: 00070963     EISSN: 13652133     Source Type: Journal    
DOI: 10.1111/j.1365-2133.2009.09352.x     Document Type: Article
Times cited : (30)

References (51)
  • 1
  • 3
    • 0030887724 scopus 로고    scopus 로고
    • Occupational contact dermatitis
    • Rietschel RL. Occupational contact dermatitis. Lancet 1997 349 : 1093 1095.
    • (1997) Lancet , vol.349 , pp. 1093-1095
    • Rietschel, R.L.1
  • 4
    • 0034025318 scopus 로고    scopus 로고
    • The diagnostic evaluation, treatment, and prevention of allergic contact dermatitis in the new millennium
    • Belsito DV. The diagnostic evaluation, treatment, and prevention of allergic contact dermatitis in the new millennium. J Allergy Clin Immunol 2000 105 : 409 420.
    • (2000) J Allergy Clin Immunol , vol.105 , pp. 409-420
    • Belsito, D.V.1
  • 5
    • 0037160751 scopus 로고    scopus 로고
    • An unexpected tattoo
    • Bowling JC, Groves R. An unexpected tattoo. Lancet 2002 359 : 649.
    • (2002) Lancet , vol.359 , pp. 649
    • Bowling, J.C.1    Groves, R.2
  • 6
    • 0036200932 scopus 로고    scopus 로고
    • Identification and quantification of para-phenylenediamine in a temporary black henna tattoo
    • Brancaccio RR, Brown LH, Chang YT et al. Identification and quantification of para-phenylenediamine in a temporary black henna tattoo. Am J Contact Dermat 2002 13 : 15 18.
    • (2002) Am J Contact Dermat , vol.13 , pp. 15-18
    • Brancaccio, R.R.1    Brown, L.H.2    Chang, Y.T.3
  • 7
    • 33845544089 scopus 로고    scopus 로고
    • Patch test frequency to p-phenylenediamine: Follow up over the last 6 years
    • Patel S, Basketter DA, Jefferies D et al. Patch test frequency to p-phenylenediamine: follow up over the last 6 years. Contact Dermatitis 2007 56 : 35 7.
    • (2007) Contact Dermatitis , vol.56 , pp. 35-37
    • Patel, S.1    Basketter, D.A.2    Jefferies, D.3
  • 8
    • 47549095842 scopus 로고    scopus 로고
    • Para-Phenylenediamine: The profile of an important allergen. Results of the IVDK
    • Schnuch A, Lessmann H, Frosch PJ et al. para-Phenylenediamine: the profile of an important allergen. Results of the IVDK. Br J Dermatol 2008 159 : 379 386.
    • (2008) Br J Dermatol , vol.159 , pp. 379-386
    • Schnuch, A.1    Lessmann, H.2    Frosch, P.J.3
  • 9
    • 33645082936 scopus 로고    scopus 로고
    • Metabolism versus chemical transformation or pro-versus prehaptens?
    • Lepoittevin JP. Metabolism versus chemical transformation or pro-versus prehaptens? Contact Dermatitis 2006 54 : 73 4.
    • (2006) Contact Dermatitis , vol.54 , pp. 73-74
    • Lepoittevin, J.P.1
  • 10
    • 0027482501 scopus 로고
    • Dissociation of allergenic and immunogenic functions in contact sensitivity to para-phenylenediamine
    • Krasteva M, Nicolas J, Chabeau G et al. Dissociation of allergenic and immunogenic functions in contact sensitivity to para-phenylenediamine. Int Arch Allergy Immunol 1993 102 : 200 204.
    • (1993) Int Arch Allergy Immunol , vol.102 , pp. 200-204
    • Krasteva, M.1    Nicolas, J.2    Chabeau, G.3
  • 11
    • 33846437066 scopus 로고    scopus 로고
    • Activation of human dendritic cells by p-phenylenediamine
    • Coulter EM, Farrell J, Mathews KL et al. Activation of human dendritic cells by p-phenylenediamine. J Pharmacol Exp Ther 2007 320 : 885 892.
    • (2007) J Pharmacol Exp Ther , vol.320 , pp. 885-892
    • Coulter, E.M.1    Farrell, J.2    Mathews, K.L.3
  • 12
    • 0036279452 scopus 로고    scopus 로고
    • Delayed-type hypersensitivity reaction to paraphenylenediamine is mediated by 2 different pathways of antigen recognition by specific alphabeta human T-cell clones
    • Sieben S, Kawakubo Y, Masaoudi TA et al. Delayed-type hypersensitivity reaction to paraphenylenediamine is mediated by 2 different pathways of antigen recognition by specific alphabeta human T-cell clones. J Allergy Clin Immunol 2002 109 : 1005 1011.
    • (2002) J Allergy Clin Immunol , vol.109 , pp. 1005-1011
    • Sieben, S.1    Kawakubo, Y.2    Masaoudi, T.A.3
  • 13
    • 53149095085 scopus 로고    scopus 로고
    • Reactivity of in vitro activated human T lymphocytes to p-phenylenediamine and related substances
    • Skazik C, Grannemann S, Wilbers L et al. Reactivity of in vitro activated human T lymphocytes to p-phenylenediamine and related substances. Contact Dermatitis 2008 59 : 203 211.
    • (2008) Contact Dermatitis , vol.59 , pp. 203-211
    • Skazik, C.1    Grannemann, S.2    Wilbers, L.3
  • 14
    • 40649127974 scopus 로고    scopus 로고
    • Activation of T-cells from allergic patients and volunteers by p-phenylenediamine and Bandrowski's base
    • Coulter EM, Jenkinson C, Wu Y et al. Activation of T-cells from allergic patients and volunteers by p-phenylenediamine and Bandrowski's base. J Invest Dermatol 2008 128 : 897 905.
    • (2008) J Invest Dermatol , vol.128 , pp. 897-905
    • Coulter, E.M.1    Jenkinson, C.2    Wu, Y.3
  • 15
    • 2942637821 scopus 로고    scopus 로고
    • Human systemic exposure to a [14C]-para-phenylenediamine-containing oxidative hair dye and correlation with in vitro percutaneous absorption in human or pig skin
    • Hueber-Becker F, Nohynek GJ, Meuling WJ et al. Human systemic exposure to a [14C]-para-phenylenediamine-containing oxidative hair dye and correlation with in vitro percutaneous absorption in human or pig skin. Food Chem Toxicol 2004 42 : 1227 1236.
    • (2004) Food Chem Toxicol , vol.42 , pp. 1227-1236
    • Hueber-Becker, F.1    Nohynek, G.J.2    Meuling, W.J.3
  • 16
    • 33745898819 scopus 로고    scopus 로고
    • Unconsumed precursors and couplers after formation of oxidative hair dyes
    • Rastogi SC, Sosted H, Johansen JD et al. Unconsumed precursors and couplers after formation of oxidative hair dyes. Contact Dermatitis 2006 55 : 95 100.
    • (2006) Contact Dermatitis , vol.55 , pp. 95-100
    • Rastogi, S.C.1    Sosted, H.2    Johansen, J.D.3
  • 17
    • 23044517246 scopus 로고    scopus 로고
    • Under the skin: Biotransformation of para-aminophenol and para-phenylenediamine in reconstructed human epidermis and human hepatocytes
    • Nohynek GJ, Duche D, Garrigues A et al. Under the skin: biotransformation of para-aminophenol and para-phenylenediamine in reconstructed human epidermis and human hepatocytes. Toxicol Lett 2005 158 : 196 212.
    • (2005) Toxicol Lett , vol.158 , pp. 196-212
    • Nohynek, G.J.1    Duche, D.2    Garrigues, A.3
  • 18
    • 0033958152 scopus 로고    scopus 로고
    • N-acetylation of paraphenylenediamine in human skin and keratinocytes
    • Kawakubo Y, Merk HF, Masaoudi TA et al. N-acetylation of paraphenylenediamine in human skin and keratinocytes. J Pharmacol Exp Ther 2000 292 : 150 155.
    • (2000) J Pharmacol Exp Ther , vol.292 , pp. 150-155
    • Kawakubo, Y.1    Merk, H.F.2    Masaoudi, T.A.3
  • 19
    • 47349115252 scopus 로고    scopus 로고
    • Expression of N-acetyltransferase in monocyte-derived dendritic cells
    • Lichter J, Heckelen A, Fischer K et al. Expression of N-acetyltransferase in monocyte-derived dendritic cells. J Toxicol Environ Health A 2008 71 : 960 964.
    • (2008) J Toxicol Environ Health A , vol.71 , pp. 960-964
    • Lichter, J.1    Heckelen, A.2    Fischer, K.3
  • 20
    • 58149331700 scopus 로고    scopus 로고
    • Skin sensitization to p-phenylenediamine: The diverging roles of oxidation and N-acetylation for dendritic cell activation and the immune response
    • Aeby P, Sieber T, Beck H et al. Skin sensitization to p-phenylenediamine: the diverging roles of oxidation and N-acetylation for dendritic cell activation and the immune response. J Invest Dermatol 2009 129 : 99 109.
    • (2009) J Invest Dermatol , vol.129 , pp. 99-109
    • Aeby, P.1    Sieber, T.2    Beck, H.3
  • 21
    • 0035045157 scopus 로고    scopus 로고
    • T cell responses to paraphenylenediamine and to its metabolites mono- and diacetyl-paraphenylenediamine
    • Sieben S, Kawakubo Y, Sachs B et al. T cell responses to paraphenylenediamine and to its metabolites mono- and diacetyl- paraphenylenediamine. Int Arch Allergy Immunol 2001 124 : 356 358.
    • (2001) Int Arch Allergy Immunol , vol.124 , pp. 356-358
    • Sieben, S.1    Kawakubo, Y.2    Sachs, B.3
  • 22
    • 44349182552 scopus 로고    scopus 로고
    • Elicitation response characteristics to mono- and to N,N'-diacetyl-para- phenylenediamine
    • Blömeke B, Pietzsch T, Merk HF. Elicitation response characteristics to mono- and to N,N'-diacetyl-para-phenylenediamine. Contact Dermatitis 2008 58 : 355 358.
    • (2008) Contact Dermatitis , vol.58 , pp. 355-358
    • Blömeke, B.1    Pietzsch, T.2    Merk, H.F.3
  • 23
    • 0025344002 scopus 로고
    • Human arylamine N-acetyltransferase genes: Isolation, chromosomal localization, and functional expression
    • Blum M, Grant DM, McBride W et al. Human arylamine N-acetyltransferase genes: isolation, chromosomal localization, and functional expression. DNA Cell Biol 1990 9 : 193 203.
    • (1990) DNA Cell Biol , vol.9 , pp. 193-203
    • Blum, M.1    Grant, D.M.2    McBride, W.3
  • 24
    • 0031011356 scopus 로고    scopus 로고
    • Human acetyltransferase polymorphisms
    • Grant DM, Hughes NC, Janezic SA et al. Human acetyltransferase polymorphisms. Mutat Res 1997 376 : 61 70.
    • (1997) Mutat Res , vol.376 , pp. 61-70
    • Grant, D.M.1    Hughes, N.C.2    Janezic, S.A.3
  • 25
    • 33645453469 scopus 로고    scopus 로고
    • Tissue distribution of N-acetyltransferase 1 and 2 catalyzing the N-acetylation of 4-aminobiphenyl and O-acetylation of N-hydroxy-4-aminobiphenyl in the congenic rapid and slow acetylator Syrian hamster
    • Hein DW, Doll MA, Nerland DE et al. Tissue distribution of N-acetyltransferase 1 and 2 catalyzing the N-acetylation of 4-aminobiphenyl and O-acetylation of N-hydroxy-4-aminobiphenyl in the congenic rapid and slow acetylator Syrian hamster. Mol Carcinog 2006 45 : 230 238.
    • (2006) Mol Carcinog , vol.45 , pp. 230-238
    • Hein, D.W.1    Doll, M.A.2    Nerland, D.E.3
  • 26
    • 0027182143 scopus 로고
    • Structural heterogeneity of caucasian N-acetyltransferase at the NAT1 gene locus
    • Vatsis KP, Weber WW. Structural heterogeneity of caucasian N-acetyltransferase at the NAT1 gene locus. Arch Biochem Biophys 1993 301 : 71 6.
    • (1993) Arch Biochem Biophys , vol.301 , pp. 71-76
    • Vatsis, K.P.1    Weber, W.W.2
  • 27
    • 0033960051 scopus 로고    scopus 로고
    • Molecular genetics and epidemiology of the NAT1 and NAT2 acetylation polymorphisms
    • Hein DW, Doll MA, Fretland AJ et al. Molecular genetics and epidemiology of the NAT1 and NAT2 acetylation polymorphisms. Cancer Epidemiol Biomarkers Prev 2000 9 : 29 42.
    • (2000) Cancer Epidemiol Biomarkers Prev , vol.9 , pp. 29-42
    • Hein, D.W.1    Doll, M.A.2    Fretland, A.J.3
  • 28
    • 38949133904 scopus 로고    scopus 로고
    • Structure-function analyses of single nucleotide polymorphisms in human N-acetyltransferase 1
    • Walraven JM, Trent JO, Hein DW. Structure-function analyses of single nucleotide polymorphisms in human N-acetyltransferase 1. Drug Metab Rev 2008 40 : 169 184.
    • (2008) Drug Metab Rev , vol.40 , pp. 169-184
    • Walraven, J.M.1    Trent, J.O.2    Hein, D.W.3
  • 29
    • 0029163025 scopus 로고
    • Polyadenylation polymorphism in the acetyltransferase 1 gene (NAT1) increases risk of colorectal cancer
    • Bell DA, Stephens EA, Castranio T et al. Polyadenylation polymorphism in the acetyltransferase 1 gene (NAT1) increases risk of colorectal cancer. Cancer Res 1995 55 : 3537 3542.
    • (1995) Cancer Res , vol.55 , pp. 3537-3542
    • Bell, D.A.1    Stephens, E.A.2    Castranio, T.3
  • 30
    • 0033675835 scopus 로고    scopus 로고
    • Pharmacogenetics of the arylamine N-acetyltransferases: A symposium in honor of Wendell W. Weber
    • Hein DW, McQueen CA, Grant DM et al. Pharmacogenetics of the arylamine N-acetyltransferases: a symposium in honor of Wendell W. Weber. Drug Metab Dispos 2000 28 : 1425 1432.
    • (2000) Drug Metab Dispos , vol.28 , pp. 1425-1432
    • Hein, D.W.1    McQueen, C.A.2    Grant, D.M.3
  • 31
    • 0345240943 scopus 로고    scopus 로고
    • Correlation between genotype and phenotype of the human arylamine N-acetyltransferase type 1 (NAT1)
    • Bruhn C, Brockmoller J, Cascorbi I et al. Correlation between genotype and phenotype of the human arylamine N-acetyltransferase type 1 (NAT1). Biochem Pharmacol 1999 58 : 1759 1764.
    • (1999) Biochem Pharmacol , vol.58 , pp. 1759-1764
    • Bruhn, C.1    Brockmoller, J.2    Cascorbi, I.3
  • 32
    • 0034893017 scopus 로고    scopus 로고
    • Functional characterization of nucleotide polymorphisms in the coding region of N-acetyltransferase 1
    • Fretland AJ, Doll MA, Leff MA et al. Functional characterization of nucleotide polymorphisms in the coding region of N-acetyltransferase 1. Pharmacogenetics 2001 11 : 511 520.
    • (2001) Pharmacogenetics , vol.11 , pp. 511-520
    • Fretland, A.J.1    Doll, M.A.2    Leff, M.A.3
  • 33
    • 0037201542 scopus 로고    scopus 로고
    • Molecular genetics and function of NAT1 and NAT2: Role in aromatic amine metabolism and carcinogenesis
    • Hein DW. Molecular genetics and function of NAT1 and NAT2: role in aromatic amine metabolism and carcinogenesis. Mutat Res 2002 506-507 : 65 77.
    • (2002) Mutat Res , vol.506-507 , pp. 65-77
    • Hein, D.W.1
  • 34
    • 0035660127 scopus 로고    scopus 로고
    • Current smoking, occupation, N-acetyltransferase-2 and bladder cancer: A pooled analysis of genotype-based studies
    • Vineis P, Marinelli D, Autrup H et al. Current smoking, occupation, N-acetyltransferase-2 and bladder cancer: a pooled analysis of genotype-based studies. Cancer Epidemiol Biomarkers Prev 2001 10 : 1249 1252.
    • (2001) Cancer Epidemiol Biomarkers Prev , vol.10 , pp. 1249-1252
    • Vineis, P.1    Marinelli, D.2    Autrup, H.3
  • 35
    • 0037051157 scopus 로고    scopus 로고
    • The enhanced bladder cancer susceptibility of NAT2 slow acetylators towards aromatic amines: A review considering ethnic differences
    • Golka K, Prior V, Blaszkewicz M et al. The enhanced bladder cancer susceptibility of NAT2 slow acetylators towards aromatic amines: a review considering ethnic differences. Toxicol Lett 2002 128 : 229 241.
    • (2002) Toxicol Lett , vol.128 , pp. 229-241
    • Golka, K.1    Prior, V.2    Blaszkewicz, M.3
  • 36
    • 34547424436 scopus 로고    scopus 로고
    • The debate on carcinogenicity of permanent hair dyes: New insights
    • Bolt HM, Golka K. The debate on carcinogenicity of permanent hair dyes: new insights. Crit Rev Toxicol 2007 37 : 521 536.
    • (2007) Crit Rev Toxicol , vol.37 , pp. 521-536
    • Bolt, H.M.1    Golka, K.2
  • 37
    • 0029062796 scopus 로고
    • Acetylation polymorphism and prevalence of colorectal adenomas
    • Probst-Hensch NM, Haile RW, Ingles SA et al. Acetylation polymorphism and prevalence of colorectal adenomas. Cancer Res 1995 55 : 2017 2020.
    • (1995) Cancer Res , vol.55 , pp. 2017-2020
    • Probst-Hensch, N.M.1    Haile, R.W.2    Ingles, S.A.3
  • 38
    • 47749126974 scopus 로고    scopus 로고
    • N-acetyltransferases: Lessons learned from eighty years of research
    • Agundez JA. N-acetyltransferases: lessons learned from eighty years of research. Curr Drug Metab 2008 9 : 463 464.
    • (2008) Curr Drug Metab , vol.9 , pp. 463-464
    • Agundez, J.A.1
  • 39
    • 0034131047 scopus 로고    scopus 로고
    • N-acetyltransferase 1 and 2 polymorphisms in para-substituted arylamine-induced contact allergy
    • Westphal GA, Reich K, Schulz TG et al. N-acetyltransferase 1 and 2 polymorphisms in para-substituted arylamine-induced contact allergy. Br J Dermatol 2000 142 : 1121 1127.
    • (2000) Br J Dermatol , vol.142 , pp. 1121-1127
    • Westphal, G.A.1    Reich, K.2    Schulz, T.G.3
  • 40
    • 33644748199 scopus 로고    scopus 로고
    • Human arylamine N-acetyltransferase 2 polymorphism and susceptibility to allergic contact dermatitis
    • Nacak M, Erbagci Z, Aynacioglu AS. Human arylamine N-acetyltransferase 2 polymorphism and susceptibility to allergic contact dermatitis. Int J Dermatol 2006 45 : 323 326.
    • (2006) Int J Dermatol , vol.45 , pp. 323-326
    • Nacak, M.1    Erbagci, Z.2    Aynacioglu, A.S.3
  • 41
    • 0035052559 scopus 로고    scopus 로고
    • Functional characterization of human N-acetyltransferase 2 (NAT2) single nucleotide polymorphisms
    • Fretland AJ, Leff MA, Doll MA et al. Functional characterization of human N-acetyltransferase 2 (NAT2) single nucleotide polymorphisms. Pharmacogenetics 2001 11 : 207 215.
    • (2001) Pharmacogenetics , vol.11 , pp. 207-215
    • Fretland, A.J.1    Leff, M.A.2    Doll, M.A.3
  • 42
    • 0344606379 scopus 로고    scopus 로고
    • Serum, plasma and paraffin-embedded tissues as sources of DNA for studying cancer susceptibility genes
    • Blömeke B, Bennett WP, Harris CC et al. Serum, plasma and paraffin-embedded tissues as sources of DNA for studying cancer susceptibility genes. Carcinogenesis 1997 18 : 1271 1275.
    • (1997) Carcinogenesis , vol.18 , pp. 1271-1275
    • Blömeke, B.1    Bennett, W.P.2    Harris, C.C.3
  • 43
    • 3042662702 scopus 로고    scopus 로고
    • N-acetyltransferase 2 genotyping: An accurate and feasible approach for simultaneous detection of the most common NAT2 alleles
    • Brans R, Laizane D, Khan A et al. N-acetyltransferase 2 genotyping: an accurate and feasible approach for simultaneous detection of the most common NAT2 alleles. Clin Chem 2004 50 : 1264 1266.
    • (2004) Clin Chem , vol.50 , pp. 1264-1266
    • Brans, R.1    Laizane, D.2    Khan, A.3
  • 44
    • 2442482408 scopus 로고    scopus 로고
    • Characterization of the sensitizing potential of chemicals by in vitro analysis of dendritic cell activation and skin penetration
    • Aeby P, Wyss C, Beck H et al. Characterization of the sensitizing potential of chemicals by in vitro analysis of dendritic cell activation and skin penetration. J Invest Dermatol 2004 122 : 1154 1164.
    • (2004) J Invest Dermatol , vol.122 , pp. 1154-1164
    • Aeby, P.1    Wyss, C.2    Beck, H.3
  • 45
    • 27744606605 scopus 로고    scopus 로고
    • Relationship of CD86 surface marker expression and cytotoxicity on dendritic cells exposed to chemical allergen
    • Hulette BC, Ryan CA, Gildea LA et al. Relationship of CD86 surface marker expression and cytotoxicity on dendritic cells exposed to chemical allergen. Toxicol Appl Pharmacol 2005 209 : 159 166.
    • (2005) Toxicol Appl Pharmacol , vol.209 , pp. 159-166
    • Hulette, B.C.1    Ryan, C.A.2    Gildea, L.A.3
  • 46
    • 17144430460 scopus 로고    scopus 로고
    • Lack of evidence for metabolism of p-phenylenediamine by human hepatic cytochrome P450 enzymes
    • Stanley LA, Skare JA, Doyle E et al. Lack of evidence for metabolism of p-phenylenediamine by human hepatic cytochrome P450 enzymes. Toxicology 2005 210 : 147 157.
    • (2005) Toxicology , vol.210 , pp. 147-157
    • Stanley, L.A.1    Skare, J.A.2    Doyle, E.3
  • 47
    • 0041816286 scopus 로고    scopus 로고
    • Redox regulation of the human xenobiotic metabolizing enzyme arylamine N-acetyltransferase 1 (NAT1). Reversible inactivation by hydrogen peroxide
    • Atmane N, Dairou J, Paul A et al. Redox regulation of the human xenobiotic metabolizing enzyme arylamine N-acetyltransferase 1 (NAT1). Reversible inactivation by hydrogen peroxide. J Biol Chem 2003 278 : 35086 35092.
    • (2003) J Biol Chem , vol.278 , pp. 35086-35092
    • Atmane, N.1    Dairou, J.2    Paul, A.3
  • 48
    • 3242880312 scopus 로고    scopus 로고
    • Regulation of the activity of the human drug metabolizing enzyme arylamine N-acetyltransferase 1: Role of genetic and non genetic factors
    • Rodrigues-Lima F, Dupret JM. Regulation of the activity of the human drug metabolizing enzyme arylamine N-acetyltransferase 1: role of genetic and non genetic factors. Curr Pharm Des 2004 10 : 2519 2524.
    • (2004) Curr Pharm des , vol.10 , pp. 2519-2524
    • Rodrigues-Lima, F.1    Dupret, J.M.2
  • 50
    • 85047693384 scopus 로고
    • Paraphenylenediamine, a contact allergen, induces oxidative stress and ICAM-1 expression in human keratinocytes
    • Picardo M, Zompetta C, Marchese C et al. Paraphenylenediamine, a contact allergen, induces oxidative stress and ICAM-1 expression in human keratinocytes. Br J Dermatol 1992 126 : 450 455.
    • (1992) Br J Dermatol , vol.126 , pp. 450-455
    • Picardo, M.1    Zompetta, C.2    Marchese, C.3
  • 51
    • 22144444117 scopus 로고    scopus 로고
    • MnSOD polymorphisms in sensitized patients with delayed-type hypersensitivity reactions to the chemical allergen para-phenylene diamine: A case-control study
    • Brans R, Dickel H, Bruckner T et al. MnSOD polymorphisms in sensitized patients with delayed-type hypersensitivity reactions to the chemical allergen para-phenylene diamine: a case-control study. Toxicology 2005 212 : 148 154.
    • (2005) Toxicology , vol.212 , pp. 148-154
    • Brans, R.1    Dickel, H.2    Bruckner, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.