A randomized comparison of rectal misoprostol with syntometrine on blood loss in the third stage of labour

West Indian Medical Journal

Volumn 58, Issue 3, 2009, Pages 201-206

  Harriott, J ^a   Christie, L ^a   Wynter, S ^a   DaCosta, V ^a   Fletcher, H ^a   Reid, M ^b  

^a UNIVERSITY HOSPITAL OF THE WEST INDIES   (Jamaica)

^b UNIVERSITY OF THE WEST INDIES   (Jamaica)

Author keywords

[No Author keywords available]

Indexed keywords

ERGOMETRINE PLUS OXYTOCIN; MISOPROSTOL; PARACETAMOL; PETHIDINE;

ADOLESCENT; ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIARRHEA; DISEASE SEVERITY; DRUG EFFECT; DRUG FEVER; DRUG TOLERABILITY; FEMALE; HUMAN; LABOR STAGE 3; MAJOR CLINICAL STUDY; NAUSEA; POSTPARTUM HEMORRHAGE; RANDOMIZED CONTROLLED TRIAL; SHIVERING; SIDE EFFECT; SYSTOLIC BLOOD PRESSURE; UTERINE ATONY; VOMITING;

ADMINISTRATION, RECTAL; ADOLESCENT; ADULT; ANALYSIS OF VARIANCE; ERGONOVINE; FEMALE; HUMANS; INJECTIONS, INTRAMUSCULAR; LABOR STAGE, THIRD; MISOPROSTOL; OXYTOCICS; OXYTOCIN; POSTPARTUM HEMORRHAGE; PREGNANCY; PROSPECTIVE STUDIES; YOUNG ADULT;

EID: 71949113289     PISSN: 00433144     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Chamberlain GVP. The clinical aspects of massive haemorrhage. In: Patel N ed. Maternal Mortality - The Way forward. London: RCOG; 1992: 54-62.
2. Drife J. Management of primary postpartum haemorrhage. Br J Obstet Gynaecol 1997; 104: 275-277
3. Alamia V, Meyer BA. Controversies in labour management. Obstet Gynaecol Clin N Am 1999; 26.
4. Enkin M, Keirse MTNC, Renfrew MJ, Neilson JP. The third stage of labour. A guide to effective care in pregnancy and childbirth. Second edition: 236-243
5. Prendiville W, Elbourne D, Chalmers I. The effect of routine oxytocic administration in management of the third stage of labour: An overview of the evidence from controlled trials. Br J Obstet Gynaecol 1988; 95: 3-16. (Pubitemid 18226223)
6. O'Brien P, El-Rafaey H, Gordon A, Greary M, Rodeck CH. Rectally administered misoprostol for the treatment of postpartum haemorrhage unresponsive to oxytocin and ergometrine: A descriptive study. Obstet Gynaecol 1998; 90: 212-214 (Pubitemid 28350850)
7. Bamigboye AA, Hofmeyr GJ, Merrell DA. Rectal misoprostol in the prevention of postpartum haemorrhage: a placebo controlled trial. Am J Obstet Gynecol 1998; 179: 1043-1046 (Pubitemid 28489305)
8. DeGroot A, Van Roosmalen J, Van Dongen PW, Borm GF. A placebo controlled trial of oral ergometrine to reduce postpartum haemorrhage. Acta Obstet Gynecol Scand 1996; 75: 464-468 (Pubitemid 26225886)
9. Ng PS, Chan AS, Sin WK, Tang LC, Cheung KB, Yuen PM. A multicentre randomized controlled trial of oral misoprostol and intra-muscular syntometrine in the management of the third stage of labour. Hum Reprod 2001; 16: 31-35
10. Cook CM, Spurrett B, Murray H. A randomized clinical trial comparing oral misoprostol with synthetic oxytocin or syntometrine in the third stage of labour. Aust N Z J Obstet Gynecol 1999; 39: 414-419
11. Diab KM, Ramy AR, Yehia MA. The use of rectal misoprostol as active pharmacological management of the third stage of labour. J Obstet and Gynecol Res 1999; 25: 327-328
12. Zieman M, Fong SK, Benowitz NL, Banskter D, Darney PD. Absorption kinetics of misoprostol with oral or vaginal administration. Obstet Gynecol 1997; 90: 88-92. (Pubitemid 27272963)
13. Hofmeyr JG, Bamigboye AA. (Letter) Rectal misoprostol in prevention of postpartum haemorrhage. Am J Obstet Gynecol 1999: 180.
14. Chong YS, Chuaa S, Shenb L, Arulkumaran S. Does the route of administration of misoprostol make a difference? The uterotonic effect and side effects of misoprostol given by different routes after vaginal delivery. Eur J Obstet Gynecol Reprod Biol 2004; 113: 191-198 (Pubitemid 38456775)
15. McCaw-Binns A, Alexander S, Lindo J, Escoffery C, Spence K, Lewis- Bell K et al. Maternal mortality in Jamaica: Challenges for the 21st century. West Indian Med J 2005; 54 (Suppl 5): 23.
16. Bradley S, Praia N, Young-Lin N, Bishai DM. Cost-effectiveness of misoprostol to control postpartum haemorrhage in low-resource settings. Int J of Gynecol and Obstet 2007; 97: 52-56 (Pubitemid 46357540)
17. Bugalho A, Daniel A, Faundes A, Cunha M. Misoprostol for prevention of postpartum haemorrhage. Int J Gynaecol Obstet 2001; 73: 1-6.
18. Brandt AA. Precise estimation of postpartum hemorrhage: Difficulties and importance. Br Med J 1967; 1: 398-400.
19. Chong YS, Chua S, El-Refaey H, Choo WL, Chanrachakul B, Tai BC et al. Postpartum intrauterine pressure studies of the uterotonic effect of oral misoprostol and intramuscular syntometrine. BJOG 2001; 108: 41-47
20. Khan RU, El-Refaey H. Pharmacokinetics and adverse effect profile of rectally administered misoprostol in the third stage of labour. Obstet Gynecol 2003; 101: 968-974 (Pubitemid 36561263)
21. Gulmezoglu AM, Villar J, Ngoc NT, Piaggio G, Carroll G, Adetoro L et al. WHO multicentre randomized trial of misoprostol in the management of the third stage of labour. Lancet 2001; 358: 689-695
22. Villar J, Gulmezoglu AM, Hofmeyr GJ, Foma F. Systematic Review of Randomized Controlled Trials of Misoprostol to Prevent Postpartum Hemorrhage. Obstet and Gynecol 2002; 100: 1301-1312 (Pubitemid 35449199)