Mechanisms of respiratory insufficiency induced by methadone overdose in rats

Addiction Biology

Volumn 15, Issue 1, 2010, Pages 62-80

  Chevillard, Lucie ^a,b   Mégarbane, Bruno ^a,b,c   Baud, Frédéric J ^a,b,c   Risède, Patricia ^a,b   Declèves, Xavier ^a,b   Mager, Donald ^d   Milan, Nathalie ^e   Ricordel, Ivan ^e  

^a UNIVERSITÉ PARIS DESCARTES   (France)

^b INSERM   (France)

^c HÔPITAL LARIBOISIÈRE   (France)

^d UNIVERSITY AT BUFFALO   (United States)

^e Centre Universitaire des Saints Pères   (France)

Author keywords

Expiratory time; Methadone; Opioid; Opioid receptor; Plethysmography; Respiratory depression

Indexed keywords

BINALTORPHIMINE; METHADONE; NALOXONAZINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIAL GAS; ARTICLE; CONTROLLED STUDY; DRUG OVERDOSE; ENANTIOMER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYPOXEMIA; INSPIRATORY CAPACITY; NONHUMAN; PLETHYSMOGRAPHY; PRIORITY JOURNAL; RAT; RESPIRATION DEPRESSION; RESPIRATORY FAILURE;

ACIDOSIS, RESPIRATORY; ANIMALS; ANOXIA; DOSE-RESPONSE RELATIONSHIP, DRUG; EXHALATION; INJECTIONS, INTRAPERITONEAL; INJECTIONS, INTRAVENOUS; INJECTIONS, SUBCUTANEOUS; MALE; METHADONE; NARCOTIC ANTAGONISTS; NARCOTICS; OVERDOSE; OXYGEN; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, OPIOID; RECEPTORS, OPIOID, DELTA; RECEPTORS, OPIOID, KAPPA; RECEPTORS, OPIOID, MU; RESPIRATORY INSUFFICIENCY;

EID: 71949111506     PISSN: 13556215     EISSN: 13691600     Source Type: Journal    
DOI: 10.1111/j.1369-1600.2009.00184.x     Document Type: Article

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