The pyrethroid metabolites 3-phenoxybenzoic acid and 3-phenoxybenzyl alcohol do not exhibit estrogenic activity in the MCF-7 human breast carcinoma cell line or Sprague-Dawley rats

Toxicology

Volumn 267, Issue 1-3, 2010, Pages 39-44

  Laffin, Brian ^a   Chavez, Marco ^a   Pine, Michelle ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

Author keywords

Endocrine disruptors; Pyrethroids; Reproductive toxicology; Risk assessment; Xenoestrogens

Indexed keywords

3 PHENOXYBENZOIC ACID; 3 PHENOXYBENZYL ALCOHOL; DRUG METABOLITE; ESTROGEN RECEPTOR ALPHA; ETHINYLESTRADIOL; LUCIFERASE; PYRETHROID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; BREAST CARCINOMA; CANCER CELL CULTURE; CELL DEATH; CELL PROLIFERATION; CELL STRAIN MCF 7; CONCENTRATION RESPONSE; CONTINUOUS INFUSION; CONTROLLED STUDY; COULTER COUNTER; DRUG CYTOTOXICITY; ESTROGEN ACTIVITY; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; ORGAN WEIGHT; PRIORITY JOURNAL; PUBERTY; RAT; SPRAGUE DAWLEY RAT; UTERUS WEIGHT; WEANING;

ANIMALS; BENZOATES; BENZYL ALCOHOLS; BREAST NEOPLASMS; CARCINOMA; CELL LINE, TUMOR; CELL PROLIFERATION; ENDOCRINE DISRUPTORS; ESTROGENS; FEMALE; GENES, REPORTER; HUMANS; INSECTICIDES; ORGAN SIZE; PUBERTY, DELAYED; PYRETHRINS; RATS; RATS, SPRAGUE-DAWLEY; TOXICITY TESTS; UTERUS;

ANIMALIA; HEXAPODA; MAMMALIA; RATTUS;

EID: 71849115530     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2009.10.003     Document Type: Article

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