Spinal cord regeneration and functional recovery: Neurotransmitter's combination and bone marrow cells supplementation

Current Science

Volumn 97, Issue 4, 2009, Pages 546-549

  Paulose, C S ^a   John, P S ^b   Sreekanth, R ^b   Philip, Mathew ^b   Mohan, C Padmarag ^b   Mathew, Jobin ^a   Kumar, T Peeyush ^a   Paul, Jes ^a   Abraham, Pretty Mary ^a   Antony, Sherin ^a   Joseph, Binoy ^a   Joseph, Anu ^a   Krishnakumar, Amee ^a   Anju, T R ^a   Khan, S Reas ^a   Thomas, K Santhosh ^a   Nandhu, M S ^a  

^a Department of Physics   (India)

^b Medical College   (India)

Author keywords

Bone marrow cells; Gamma aminobutyric acid; Neurotransmitters; Serotonin; Spinal cord

Indexed keywords

RATTUS; RATTUS NORVEGICUS;

EID: 71849108126     PISSN: 00113891     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Martin, E. S., Regenerative nerve fiber growth in the adult central nervous system. News Physiol. Sci., 1998, 13, 294-298.
2. Treherne, J. M. et al., Restoration of conduction and growth of axons through injured spinal cord of neonatal opossum in culture. Proc. Natl. Acad. Sci. USA, 1992, 89, 431-434.
3. Case, L. C. and Tessier-Lavigne, M., Regeneration of the adult central nervous system. Curr. Biol., 2005, 15, 749-753.
4. 2 receptor. Hepatology, 1998, 27, 62-66.
5. Biju, M. P., Pyroja, S., Rajesh, K. N. V. and Paulose, C. S., Hepatic GABA A receptor functional regulation during liver cell proliferation. Hepatol. Res., 2001, 21, 136-146.
6. Luyt, K. et al., Developing oligodendrocytes express functional GABA(B) receptors that stimulate cell proliferation and migration. J. Neurochem., 2007, 100, 822-840.
7. Murrain, M., Murphy, A. D., Mills, L. R. and Kater, S. B., Neuronspecific modulation by serotonin of regenerative outgrowth and intracellular calcium within the CNS of Helisoma trivolvis. J. Neurobiol., 1990, 21, 611-618.
8. Noam, Y. H. and Stephen, M., Strittmatter can regenerating axons recapitulate developmental guidance during recovery from spinal cord injury. Nat. Rev. Neurosci., 2006, 7, 603-616.
9. Kawahara, H., Nakakita, S., Ito, M., Niwa, K., Kawahara, D. and Matsuda, S., Electron microscopic investigation on the osteogenesis at titanium implant/bone marrow interface under masticatory loading. J. Mater. Sci., 2006, 17, 717-726.
10. Mari, D. et al., Potential of bone marrow stromal cells in applications for neuro-degenerative, neuro-traumatic and muscle degenerative diseases. Curr. Neuropharmacol., 2005, 3, 257-266.
11. Jerry, I. et al., Upregulation of neurotransmitter receptors - a possible mechanism for accelerated fracture healing. Basic Sci., 2006, 20, 31-39.
12. Paulose, C. S. and Dakshinamurti, K., Chronic catheterization using vascular-access-port in rats: blood sampling with minimal stress for plasma catecholamine determination. J. Neurosci. Methods, 1987, 22, 141-146.
13. Cajal, S. R. Y., Degeneration and Regeneration of the Nervous System, Oxford University Press, London, 1928.
14. Pittenger, M. F. et al., Multilineage potential of adult human mesenchymal stem cells. Science, 1999, 284, 143-147.
15. Reyes, M. et al., Origin of endothelial progenitors in human postnatal bone marrow. J. Clin. Invest., 2002, 109, 337-346.
16. Bianco, P., Riminucci, M., Gronthos, S. and Robey, P. G., Bone marrow stromal cells: nature, biology, and potential applications. Stem Cells, 2001, 19, 180-192.
17. Hofstetter, C. P. et al., Marrow stromal cells form guiding strands in the injured spinal cord and promote recovery. Proc. Natl. Acad. Sci. USA, 2002, 99, 2199-2204.
18. Kopen, G. C., Prockop, D. J. and Phinney, D. G., Marrow stromal cells mitigate throughout forebrain and cerebellum, and they differentiate into astrocytes after injection into neonatal mouse brains. Proc. Natl. Acad. Sci. USA, 1999, 96, 10711-10716.
19. Deng, W., Obrocka, M., Fischer, I. and Prockop, D. J., In vitro differentiation of human marrow stromal cells into early progenitors of neural cells by conditions that increase intracellular cyclic AMP. Biochem. Biophys. Res. Commun., 2001, 282, 148-152.
20. Chopp, M. et al., Spinal cord injury in rat: treatment with bone marrow stromal cell transplantation. NeuroReport, 2000, 11, 3001-3005.
21. Wu, S. et al., Bone marrow stromal cells enhance differentiation of co-cultured neurosphere cells and promote regeneration of injured spinal cord. J. Neurosci. Res., 2003, 72, 343-351.
22. Michael, D. et al., Repeated pulses of serotonin required for longterm facilitation activate mitogen-activated protein kinase in sensory neurons of Aplysia kandel. Proc. Natl. Acad. Sci. USA, 1998, 95, 1864-1869.
23. Takehara, A. et al., A new role for an old molecule: serotonin as a mitogen B. AJP Lung Cell. Mol. Physiol., 1997, 272, L795-L806.
24. Takehara, A. et al., Gamma-aminobutyric acid (GABA) stimulates pancreatic cancer growth through over expressing GABAA receptor π subunits. Cancer Res., 2007, 67, 9704-9712.