Chlorophytum borivilianum: A white gold for biopharmaceuticals and neutraceuticals

Current Pharmaceutical Biotechnology

Volumn 10, Issue 7, 2009, Pages 650-666

  Thakur, Gulab Singh ^a   Bag, Manoranjan ^a   Sanodiya, Bhagwan S ^a   Debnath, Mousumi ^b   Zacharia, Anish ^c   Bhadauriya, Pratiksha ^c   Prasad, G B K S ^c   Bisen, P S ^a  

^a Bisen Biotech and Biopharma Pvt Ltd   (India)

^b Jaipur Engineering College and Research Centre   (India)

^c JIWAJI UNIVERSITY   (India)

Author keywords

Antioxidant; Aphrodisiac agent; Chlorophytum borivilianum; In vitro tuber induction; Saponins

Indexed keywords

ALCOHOL; ANALGESIC AGENT; ANTIDIABETIC AGENT; ANTIOXIDANT; CHLOROPHYTUM BORIVILIANUM EXTRACT; FRUCTAN; GLIBENCLAMIDE; NUTRACEUTICAL; PLANT EXTRACT; SAPONIN; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ANGIOSPERM; ANTIOXIDANT ACTIVITY; ARTHRITIS; CANDIDIASIS; CHLOROPHYTUM BORIVILIANUM; CLASSIFICATION; CONSERVATION BIOLOGY; CYTOLOGY; DIABETES MELLITUS; DRUG DETERMINATION; DRUG DOSE COMPARISON; DRUG ISOLATION; DRUG MECHANISM; DRUG STRUCTURE; ERECTILE DYSFUNCTION; GYNECOLOGIC DISEASE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HYPERCHOLESTEROLEMIA; HYPERGLYCEMIA; HYPOGLYCEMIA; IMMUNOMODULATION; IMPOTENCE; IN VITRO PROPAGATION; LIPID METABOLISM; MARKETING; MICROPROPAGATION; NONHUMAN; OLIGOSPERMIA; PAIN; PHYSICAL DISEASE; PHYTOCHEMISTRY; PLANT DISEASE; PLANT REPRODUCTION; PLANT ROOT; PLANT TUBER; PREMATURE EJACULATION; REVIEW; SINGLE DRUG DOSE; THIN LAYER CHROMATOGRAPHY; VEGETATIVE PROPAGATION; WEAKNESS;

ANALGESICS; ANIMALS; ANTILIPEMIC AGENTS; ANTIOXIDANTS; APHRODISIACS; BIOLOGICAL PRODUCTS; DIETARY SUPPLEMENTS; HUMANS; HYPOGLYCEMIC AGENTS; IMMUNOLOGIC FACTORS; INDIA; LILIACEAE; PLANT DISEASES; PLANT ROOTS; STRESS, PSYCHOLOGICAL;

CHLOROPHYTUM BORIVILIANUM; LILIACEAE;

EID: 71849096573     PISSN: 13892010     EISSN: 18734316     Source Type: Journal    
DOI: 10.2174/138920109789542084     Document Type: Review

References (119)

1. Prakash, V. (2001) Indian medicinal plants; current status. in Himalayan Medicinal Plants Potential and Prospects, (Samanth, S.S.; Dhar, U.and Palni, L.M.S., Ed.). Gyan Odaya Prakashan Publisher, Nainital, pp. 45-63.
2. Kaushik, N. (2005) Saponins of Chlorophytum species. Phytochem. Rev., 4, 191-196.
3. Handa, S.S. (1996) Rasayana Drugs. in Supplement to Cultivation and Utilization of Medicinal Plants, (Handa, S.S. and Kaul, M.K. Ed.) Regional Research Laboratory, CSIR Jammu-Tawi, pp. 509-513.
4. Kumar, A.; Nandi, S.K.; Chandra, B. and Pal, M. (2004) Conservation of some Himalayan medicinal plants using biotechnological approaches. Indian Forest., 130,187-199.
5. Kirtikar, K.R. and Basu, B.D. (1975) Liliaceae: Chlorophytum. in Indian Medicinal Plants (Kirtikar, K. R. and Basu, D., Ed.), L.M. Basu, Publishers, Allahabad, pp. 2508-2509.
6. Oudhia, P. and Tripathi, R.S. (1999) In: Proceedings National Conference on Health care and Development of Herbal Medicines. Indira Gandhi Agricultural University: Raipur, India, pp. 71-78.
7. Bordia, P.C.; Joshi, A. and Simlot, M.M. (1995) "Safed Musli" in Advances in Horticulture: Medicinal and Aromatic Plants, (Chadha, K.L. and Gupta, R., Ed.), Malhotra Publishing House: New Delhi, pp. 440-449.
8. Triveni, A. (1977) Rasendrasarasangrah: Vajikaranadhikar. Nutan Press, Rajkot, pp. 617-643.
9. nd ed., L.M. Basu, Publishers, Allahabad, pp. 235-246.
10. Sharma, S.K.; Chunekar, K.C. and Paudal, K. (1999) Plants of Sharangdhar Samhita, RAV Publications, New Delhi, pp. 221-222.
11. Tandon, M. and Shukla, Y.N. (1995) Phytoconstituents of Asparagus adescendens, Chlorophytum arundinaceum and Curculigo orichoides: a review. CROMAP, 12, 202-204.
12. Kothari, S.K. (2004) Safed Moosli (Chlorophytum borivilianum) revisited. J. Med. Arom. Plant Sci., 26, 60-63.
13. Puri, H.S. (2003) Rasayana - Ayurvedic Herbs for Longevity and Rejuvenation. Taylor and Francis Group Publishers: London, pp. 212-224.
14. st ed. Chaukambha Surbharti Prakashan, Varanasi, pp. 1008-1133.
15. Siddiqui, Y. M. (2005) Potent antiviral effect of Safed musli on poliovirus replication, International conference on promotion and development of botanicals with international co-ordination exploring quality, safety, efficacy and regulation organized by School of natural product study, Jadavpur university, Kolkata, India, p. 25.
16. Jamal, M. A. (2005) Effects of Safed musli on cell kinetics and apoptosis in human breast cancer cell lines. International conference on promotion and development of botanicals with international co-ordination exploring quality, safety, efficacy and regulation organized by School of natural product study, Jadavpur university, Kolkata, India, p. 26.
17. Govindarajan, R.; Sreevidya, N.; Vijayakumar, M.; Thakur, M.; Dixit, V.K.; Mehrotra, S. and Pushpangadan, P. (2005a) Standardization and determination of antioxidant activity of Chlorophytum borivilianum. Nat. Prod. Sci., 11(3), 165-169.
18. Govindarajan, R.; Vijayakumar, M. and Pushpangadan, P. (2005b) Antioxidant approach to disease management and the role of 'Rasayana' herbs of Ayurveda. J. Ethnopharmacol., 99, 165-178.
19. Kenjale, R.D.; Shah, R.K. and Sathaye, S.S. (2007) Anti-stress and anti-oxidant effects of roots of Chlorophytum borivilianum (Santa Pau & Fernandes). Indian J. Exp. Biol., 45(11), 974-979.
20. Sreevidya, N.; Govindarajan, R.; Vijayakumar, M.; Thakur, M.; Dixit, V.K.; Mehrotraand, S. and Madhusudan, K.P. (2006) Action of fructo-oligo polysaccharide fraction of Chlorophytum borivilianum against streptozotocin induced oxidative stress. Planta Med., 72, 1421-1424.
21. Thakur, M. and Dixit, V. K (2007) Effect of some vajikaran herbs on pendiculation activities and in vitro sperm count in male. Sex Disabil., DOI 10.1007/s11195-9051-y.
22. Panda, S.K.; Si, S.C. and Bhatnagar, S.P. (2007) Studies on hypoglycaemic and analgesic activities of Chlorophytum borivilianum Sant & Ferz. J. Nat. Remedies, 7(1), 31-36.
23. Mujeeb, M.; Khan, S.A.; Ali, M.; Mall, A. and Ahmad, A. (2009) Anti-diabetic activity of the aqueous extract of Chlorophytum borivilianum L. in Streptozotocin induced- hyperglycemic rats- a preliminary study. J. Pharm. Res., 2(1), 51-53.
24. Gopalkrishna, B.; Akki, S. and Patil, H. (2006) Preliminary phytochemical investigation and invitro anti-stress activity of Safed musli - Chlorophytum borivilianum. Ind. Drugs, 43 (11), 878-880.
25. Deore, S.L. and Khadabadi, S.S. (2009b) Screening of antistress properties of chlorophytum borivilianum tuber. Pharmacologyonline, 1, 320-328.
26. Thakur, M. and Dixit, V.K. (2006a) Effect of Chlorophytum borivilianum root extracts on androgenic and sexual behavior in male rats. Indian Drugs, 43(4), 300-306.
27. Kenjale, R.; Shah, R. and Sathaye, S. (2008) Effects of Chlorophytum borivilianum on sexual behaviour and sperm count in male rats. Phytother. Res., 22(6), 796-801. (Pubitemid 351955579)
28. Thakur, M.; Chauhan, N. S.; Bhargava, S. and Dixit, V. K. (2009) A comparative study on aphrodisiac activity of some ayurvedic herbs in male albino rats. Arch. Sex Behav., DOI 10.1007/s 10508-008-9444-9448.
29. Deore, S. L. and Khadabadi S. S. (2007) In vitro antimicrobial studies of Chlorophytum borivilianum (liliaceae) root extracts. Asian J. Microbiol. Biotech. Environ. Sci., 9(4), 807-809.
30. Visavadiya, N.P. and Narsimhacharya, A.V.R.L. (2007) Ameliorative effect of Chlorophytum borivilianum root on lipid metabolism in hyperlipaemic rats. Clin. Exp. Pharmacol. Physiol., 34(3), 244-249.
31. Deore, S.L. and Khadabadi, S.S. (2009a) A study of hypocholesteremic effects of Chlorophytum borivilianum tubers in rats. Pharmacologyonline, 1, 398-403.
32. Loo, J.V.; Clune, Y.; Bennett, M. and Collins, J.K. (2005) The specificity of interaction with intestinal bacterial fermentation by prebiotics determines their physiological efficacy. Br. J. Nutr., (Suppl. 1), 91-98.
33. Deore, S. L. and Khadabadi S. S. (2008) Anti-Inflammatory and antioxidant activity of Chlorophytum borivilianum root extracts. Asian J. Chem., 20 (2), 983-986.
34. Thakur, M.; Bhargava, S. and Dixit, V. K. (2006b) Immunomodulatory Activity of Chlorophytum borivilianum Sant. F. eCAM, DOI: 10.1093/ecam/nel094, pp. 1-5.
35. Flemming, K. B. (1985) Reticuloendothelial System: A Comprehensive Treatise, Academic press, New York, Vol.8, pp. 247-284.
36. Kowalozyk-Bronisz, S. H. and Paegelow, I. (1986) The influence of immunomodulators on lymphokine secretion of radiationdamaged lymphocytes. Allerg. Immunol., 32(1), 57-64.
37. Smirnov, L.D. and Suskova, V. S. (1989) Modulation of an immune- response of antioxidants. Khim.-farm. Zh., 7, 773-784.
38. Patwardhan, B.; Kalbag, D.; Patki P. S.; and Nagsampagi, B. A. (1990) Search of immunomodulatory agents: a review. Indian Drugs, 28(2), 348-358.
39. Smith, G. E. (1974) Papyrus Ebers. Ares Publishers, Chicago, p. 167.
40. Hooper, A. (2002) Kamasutra: Classic Love Making Techniques Reinterpreted for Today's Lovers, D.K. Publishing, Hongkong, p. 71.
41. Zimmet, P. (2000) Globalization, coca-colonization and the chronic disease epidemic: can the doomsday scenario be averted? J. Int. Med., 247, 301-310.
42. Wild, S.; Roglic, G.; Green, A.; Sicree, R. and King, H. (2004) Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care, 27, 1047-1053. (Pubitemid 38579764)
43. Padmini, K. and Chakrabarti, C.H. (1982) Effects of Bittergourd (Momordica charantia) seed and glibenclamide in streptozotocin-induced diabetes mellitus. Indian J. Exp. Biol., 20, 232-235.
44. Nayar, M.P. and Sastry, A.R. (1988) Chlorophytum borivilianum, in M.P., Red Data Book of Indian Plants, Botanical Survey of India: Calcutta, India, 2, pp. 375-378.
45. Li, X.C.; Wang, D.Z. and Yang, C.R. (1990) Steroidal saponins from Chlorophytum malayense. Phytochemistry, 29(12), 3893-3898.
46. Kavitu, S. and Nordal, I. (1993) New combination of African species in the genus Chlorophytum (Anthericaceae). Nordic J. Bot., 13, 59-65.
47. nd Indian reprint 1988, Periodical Experts Book Agency, Delhi, Vol.III.
48. Cooke, T. (1908) Flora of the Presidency of Bombay, Indian ed. 1997, Bishen Singh Mahendra Pal Singh, Dehradun, India, Vol.II, pp. 771-774.
49. Hooker, J.D. (1894) The Flora of British India, New ed., reprinted 1997, Bishen Singh Mahendra Pal Singh, Dehra Dun, India, Vol.VI.
50. Santapau, H. and Fernandes, R.R. (1954) A new species of Chlorophytum from Salsette Island. J. Bombay Nat. Hist. Soc., 52, 896-900.
51. Purohit, S.D.; Dave, A. and Tiagi, Y.D. (1994b) Chlorophytum borivlianum Sant. and Fern. An (Liliaceae) interesting species from the Aravallis in Rajasthan. Rheedea, 4, 113-115.
52. Aundhe, D.J. and Deokule, S.S. (2001) Studies on root morphology of Chlorophytum Ker-Gawl. J. Phytol. Res., 14, 195-197.
53. Sheriff, A. and Chennaveeraiahm, M.S. (1972) Karyomorphology of four diploid species of Chlorophytum. Nucleus, 15, 45.
54. Satyabrata, M. and Geetha, K. A. (2005) Characterization, genetic improvement and cultivation of Chlorophytum borivilianum-an important medicinal plant of India. Plant Genet. Resour., 3(2), 264-272.
55. Raghavan, S.R.; Ansari, M.Y. and Kamble, S.Y. (1977) Cytotaxaonomic studies in Chlorophytum Ker-Gawl. (Liliaceae). Curr. Sci., 46, 534-535.
56. Geetha, K.A and Maiti, S. (2004) New basic chromosome number in Chlorophytum borivilianum Santapau and Fernandes. J. Spices Arom. Crops, 13, 121-123.
57. Lavania, U.C.; Basu, S.; Srivastava, S.; Mukai, Y. and Lavania, S. (2005) In situ chromosomal localization of rDNA sites in 'Safed musli' Chlorophytum ker-Gawl and their physical measurement by Fiber FISH. J. Hered., 96, 155-160.
58. nd ed. George Allan and Unwin: London.
59. Naik, V.N. (1977a) Erroneous report of the new basic chromosome number in Chlorophytum. Sci. Cult., 43, 260-261.
60. Naik, V.N. (1977b) Cytotaxonomic studies of six Indian species of Chlorophytum. Bot. J. Linnaeus Soc., 74, 297-308.
61. John, C.K.; Somani, V.J. and Thengane, R.J. (1989) Some interesting features of male meiosis in Chlorophytum tuberosum Baker. Curr. Sci., 58, 254-255.
62. Naik, V.N. and Nirgude, S.M. (1981) Anatomy in relation to taxonomy of Chlorophytum (Liliaceae). Indian J. Bot., 4, 48-60.
63. Kumar, L.S.S. and Rao, H.K.S. (1958) Chromosome number in Chlorophytum tuberosum Baker. Curr. Sci., 27, 406-407.
64. Pahuja, A.N. and Kumar, V. (1969) Cytogeography of three species of Chlorophytum. Curr. Sci., 38, 469-471.
65. Aparna, V. (2000) Evaluation of reproductive patterns and clonal propagation of two rare taxa for biodiversity conservation. Ph.D Thesis, Sardar Patel University: Gujarat, India.
66. Geetha, K.A. and Maiti, S. (2001) Reproductive biology of Chlorophytum borivilianum. J. Trop. Med. Plants, 2, 287-290.
67. Soule, M. E. and Wilcox, B. A. (1980) Conservation Biology: An Evolutionary-Ecological Perspective, (Soule, M. E. and Wilcox, B. A.; Ed.) Sinauer Associates, Sunderland, Massachusetts, pp. 95-117.
68. Soule, M. E. (1986) What is conservation biology? BioScience, 35(11), 727-734.
69. Jat, R.D. (1993) Study on variability and micropropagation in Safed musli (Chlorophytum borivilianum). M.Sc. Thesis, Rajasthan College of Agriculture: Udaipur, India.
70. Shrivastava, D.K.; Mishra, P.K.; Gangrade, S.K. and Verma, S. (2001) Studies on propagation methods and dormancy in Safed musli (Chlorophytum spp.). J. Med. Arom. Plant Sci., 22, 275-276.
71. Mandal, K.; Maiti, S.; Saxena, D.R. and Saxena, M. (2004) A new leaf spot disease of Safed musli. J. Mycol. Plant Pathol., 34, 162-163.
72. Singh, H.B.; Singh, A.; Tripathi, A.; Tiwari, S.K. and Johri, J.K. (2001) Collar rot of Chlorophytum borivilianum caused by corticium rolfsii: a new disease. EPPO Bull., 31, 112-113.
73. Singh, A.; Khanuja, S.P.S. and Singh, S. (2003) Agronomic practices for the production of Safed musli (Chlorophytum borivilianum Santapau & Fernandes) in India. Nat. Prod. Rad., 2(6), 308-313.
74. Pandey, R. (2003) Root-knot disease of Safed musli. Indian J. Nemat., 33, 64.
75. Oudhia, P. (2000) Record of orange banded blister beetle, Zonabris pustulata Thunb. [Mylabris pustulata] (Coleoptera: Meloidae) on safed musli (Chlorophytum borivilianum). Insect Environ., 6, 138.
76. Sattar, A.; Alam, M.; Khaliq, A.; Shukla, R. S. and Khanuja, S. P. S. (2006) First report of a leaf blight disease of Chlorophytum borivilianum caused by Colletotrichum capsici in northern India. Plant Pathol., 55(2), 301.
77. Bordia, P.C. and Jat, R.D. (1990) Comparative performance of transplanted seedlings of Safed musli (Chlorophytum species) from sexual and asexual means. Crop Breed. NewsLett, 1, 14-15.
78. Zimmer, K. (1979) Effects of Photoperiod on Runner Formation of Chlorophytum-comosum Cultivar Variegatum. Gartenbauwissenschaf., 44, 247-250
79. Mortenson, L.M. (1991) The effect of air temperature on the growth of foliage plants. Norwegian J. Agric. Sci., 5, 289-294.
80. Bordia, P.C. (1993) Development of Suitable Culture of Safed Musli (Chlorophytum species) for Root Yield and Acceptable Medicinal Quality, ICAR Project, R.C.A, Udaipur.
81. Jat, R.D. and Bordia, P.C. (1990) Propagation studies in Safed Musli (Chlorophytum species) Proc. of National symposium on Adv. In Plant Sci.: Current Status and Emerging Challenges. Deptt. of Botany, Sukhadia Univ., Udaipur, 46.
82. Ramawat, K.G.; Rachna, S.; Jain, S. and Suri, S.S. (1996) Problem of Propagation of Desert Plants: Seed Biology and Biotechnological Approaches. Proc. Seed Tech. Garhwal Uni. Srinagar, pp. 98-100.
83. Biswas, S.; Jain, S. and Pal, M. (2003) Research needs and priorities for conservation of Indian medicinal flora. Indian Forest., 129, 85-92.
84. Honda, H.H. and Kobayashi, T. (2004) Large-Scale Micropropagation System of Plant Cells Recent Progress of Biochemical and Biomedical Engineering in Japan II. Springer Publishers, Berlin / Heidelberg, pp.105-134.
85. Purohit, S.D.; Dave, A. and Kukda, G. (1994a) Micropropagation of Safed Musli (Chlorophytum borivilianum), a rare Indian medicinal herb. Plant Cell Tiss. Organ Cult., 39, 93-96.
86. Purohit, S.D.; Dave, A. and Kukda, G. (1994c) Somatic Embryogenesis and plantlet regeneration in 'Safed Musli' (Chlorophytum borivilianum). Ind. J. Pl. Gene Res., 7, 65-71.
87. Dave, A. and Purohit S. D. (2002) Factors influencing In vitro culture of Chlorophytum borivilianum. Oikoassay, 15, 19-27.
88. Dave, A.; Joshi, N. and Purohit, S.D. (2004) In vitro propagation of Chlorophytum borivilianum using encapsulated shoot buds. Eur. J. Horticult. Sci., 69(1), 37-42. (Pubitemid 38522179)
89. Debnath, M.; Malik, C.P. and Bisen, P.S. (2006) Micropropagation: A tool for the production of high quality plant-based medicines. Curr. Pharm. Biotechnol., 7, 33-49.
90. Debnath, M.; Malik, C.P. and Bisen, P.S. (2007) Clonal propagation of Chlorophytum borivilianum- An endangered medicinal plant. Phytomorphology, 57, 117-121.
91. Rhizvi, M.Z.; Kukreja, A.K. and Knanuja, S.P.S. (2007) In vitro culture of Chlorophytum borivilianum Sant .et. Fernand .in liquid culture medium as a cost effective measure. Curr. Sci., 92(1), 87-90.
92. Debnath, M. (2005) In vitro Plantlet Production System for Chlorophytum borivilianum, A Rare Indian Medicinal Herb, 92nd Indian Science Congress Association, Ahmedabad, India, pp. 106-107.
93. Mathur, A.; Ajay, K. M.; Priyanka, V.; Shrawan, Y.; Moti, L. G. and Mahendra, P. D. (2008) Biological hardening and genetic fidelity testing of micro-cloned progeny of Chlorophytum borivilianum Sant. et Fernand. Afr. J. Biotechnol., 7 (8), 1046-1053.
94. Arora, D.K.; Suri, S.S.; Ramawat, K.G. and Merillon, J.M. (1999) Factors affecting somatic embryogenesis in long term callus cultures of safed musli (Chlorophytum borivilianum) - an endangered wonder herb. Indian J. Exp. Biol., 37, 75-82.
95. Dave, A.; Bilochi, G. and Purohit, S.D. (2003) Scale-up production and field performance of micropropagated medicinal herb 'Safed musli' (Chlorophytum borivilianum). In Vitro Cell Dev. Biol. Plant., 39, 419-424.
96. Estrada, R.; Tavar, P. and Dodds, J.H. (1986) Induction of in vitro tubers in a broad range of potato genotypes. Plant Cell Tiss. Organ. Cult., 7, 3-10.
97. Veramendi, J.; Sota, V. and Fernandez-San, MA. (2000) An in vitro tuberization bioassay to assess maturity class of new potato clones. J. Horticult. Sci. Biotech., 75(6), 733-738.
98. Ewing, E.E. and Wareing, P.F. (1978) Shoot, Stolon, and Tuber Formation on Potato (Solanum tuberosum L.) cuttings in Response to Photoperiod. Physiology, 61(3), 348-353.
99. Mandi, M. and Dobranszki, J. (1993) Induction of in vitro tuberization by short day period and dark treatment of potato shoots grown on hormone-free medium. Acta. Biol. Hung., 44(4), 411-420.
100. Hussey, G. and Stacey, N.J. (1984) Factors affecting the formation of in vitro tubers of Potato (Solanum tuberosum L.). Ann. Bot., 53, 565-578.
101. Xu, X.; Van Lammeren, A.A.M.; Vermeer, E. and Vreugdenhil, D. (1998) The role of gibberellins, abscisic acid, and sucrose in the regulation of potato tuber formation in vitro. Plant Physiol., 117, 575-584. (Pubitemid 128652830)
102. Wagle, A.; Kelkar, G. D. and Heble, M. R. (2000) in Biotechnology: Secondary Metabolites, Oxford and IBH Publishing Co, Pvt. Ltd., New Delhi, pp. 219-220.
103. Kothari, S.K. (2004) Safed Moosli (Chlorophytum borivilianum) revisited. J. Med. Aromat. Plant Sci., 26, 60-63.
104. Devon, T.K. and Scott, A.I (1976) Handbook of Naturally Occurring Compounds, Academic Press, New York, Vol. I, p. 498.
105. Thakur, M. and Dixit, V.K. (2005) Fructan; The polymer with unexplored potential. Ind. Pharm., 4(40), 7-12.
106. Tandon, M. and Shukla, Y.N. (1992) Sapogenins from Asparagus adscendens and Chlorophytum arundinaceum. J. Indian Chem. Soc., 69, 893.
107. Tandon, M. and Shukla, Y.N. (1995) Phytoconstituents of Asparagus adscendens, Chlorophytum arundinaceum and Curculigo orchioides: a review. Curr. Res. Med. Aromat. Plants, 17, 202-210.
108. Tandon, M. and Shukla, Y.N. (1996) Arundinoside B, a new acylated glucoside from Chlorophytum arundinaceum. J. Indian Chem. Soc., 35, 988-989.
109. Tandon, M. and Shukla, Y.N. (1997) Arundinoside A- a new spirostane from Chlorophytum arundinaceum. J. Indian Chem. Soc., 74, 56-58.
110. Joshi, A.; Ganesh, R.; Sharma, A. and Audichya, P. (2000) Sapogenin content determination in Chlorophytum borivilianum. Bionature, 20, 47-49.
111. Von Steiner, M. and Holtze, H. (1954) Triterpene and triterpine saponin. Modern Method of Plant Analysis. Springer Verlag, Berlin, Vol. 3, p. 64.
112. Oudhia, P. (2001) Problems perceived by Safed Moosli (Chlorophytum borivilianum) growers of Chattisgarh (India) region: A study. J. Med. Aromat. Plants Sci., DOI 22/4A & 23/1A, 396-399.
113. Thakur, M. (2005) Phytochemical and Pharmacological studies on Chlorophytum borivilianum Sant. & F., M. Pharm Thesis, Department of Pharmaceutical Sciences, Dr. H.S. Gour University, Sagar.
114. th ed., Lea & Ferbiger Publisher, Philadelphia, p. 67.
115. Bruneton, J. (1995) Pharmacognosy, Phytochemistry, Medicinal Plants. Lavoisier Publishing, Paris, pp. 538-544.
116. Estrada, A.; Katselis, G.S.; Laarveld, B. and Barl, B. (2000) Isolation and evaluation of immunological adjuvant activities of saponins from Polygala senega L. Microbiol. Infect. Dis., 23, 27-43. (Pubitemid 30069602)
117. Liu, J. and Henkel, T. (2002) Traditional Chinese medicine (TCM): are polyphenols and saponins the key ingredients triggering biological activities? Curr. Med. Chem., 9, 1483-1485. (Pubitemid 34823028)
118. Simone, C.B.G.; Schenkel, E.P. and Valquiria, L.B. (2005) HPLC method to assay total saponins in Ilex paraguariensis aqueous extract. J. Braz. Chem. Soc., 16 (4), 723-726.
119. Jaykumar, B.; Sagar, S.K. and Sinnathurai, G. (2008) Neutraceutical compositions and methods of use of Safed Musli extracts. Patent No. WO/2008/020451 A2.