Synthesis, stereochemistry and antimicrobial studies of novel oxime ethers of aza/diazabicycles

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 24, 2009, Pages 6981-6985

  Parthiban, Paramasivam ^a,b   Aridoss, Gopalakrishnan ^a,b   Rathika, Paramasivam ^a   Ramkumar, Venkatachalam ^c   Kabilan, Senthamaraikannan ^a  

^a ANNAMALAI UNIVERSITY   (India)

^b Pukyong National University   (South Korea)

^c INDIAN INSTITUTE OF TECHNOLOGY MADRAS   (India)

Author keywords

3,7 DABN; 3 ABN; Antibacterial activity; Antifungal activity; Oxime ether; Single crystal XRD; Stereochemistry

Indexed keywords

AMPHOTERICIN B; ANTIINFECTIVE AGENT; CIPROFLOXACIN; OXIME DERIVATIVE;

ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ANTIMICROBIAL ACTIVITY; ARTICLE; ASPERGILLUS FLAVUS; ASPERGILLUS NIGER; CANDIDA ALBICANS; CONTROLLED STUDY; CRYSTAL STRUCTURE; DILUTION; DRUG INHIBITION; DRUG SCREENING; DRUG SYNTHESIS; ESCHERICHIA COLI; IN VITRO STUDY; KLEBSIELLA PNEUMONIAE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PSEUDOMONAS AERUGINOSA; RHIZOPUS; SALMONELLA TYPHI; STAPHYLOCOCCUS AUREUS; STEREOCHEMISTRY;

ANTI-BACTERIAL AGENTS; ANTIFUNGAL AGENTS; BACTERIA; BICYCLO COMPOUNDS; ETHERS; FUNGI; OXIMES;

ASPERGILLUS FLAVUS; ASPERGILLUS NIGER; CANDIDA; CANDIDA ALBICANS; ESCHERICHIA COLI; FUNGI; KLEBSIELLA PNEUMONIAE; PSEUDOMONAS AERUGINOSA; RHIZOPUS; SALMONELLA TYPHI; STAPHYLOCOCCUS AUREUS;

EID: 71849094613     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.10.042     Document Type: Article

References (28)

1. Gastmeier P., Sohr D., Geffers C., Behnke M., Daschner F., and Rüden H. Infection 33 (2005) 50
2. Potera C. Science 46 (1999) 4830
3. Talbot G.H., Bradley J., Edwards J.E., Gilbert D., Scheld M., and Bartlett J.G. Clin. Infect. Dis. 42 (2006) 657
4. Gastmeier P., Sohr D., Geffers C., Behnke M., and Ruden H. Infect. Control Hosp. Epidemiol. 28 (2007) 466
5. Facts sheet-Swiss Hand Hygiene Campaign, 2007, http://www.swiss-noso.ch.
6. http://www.wrongdiagnosis.com/n/nosocomial_infections/stats-country.
7. Fridkin S.K., and Jarvis W.R. Clin. Microbiol. Rev. 9 (1996) 499
8. Marr K.A. Oncology 18 (2004) 9
9. Prasad R., and Kapoor K. Int. Rev. Cytol. 242 (2004) 215
10. Akins R.A. Med. Mycol. 42 (2005) 285
11. Wang F.P., and Liang X.T. In: Cordell G.A. (Ed). The Alkaloids: Chemistry and Pharmacology Vol. 42 (1992), Academic, New York 151
12. Dzhakhagirov F.N., Sultankhodzhaev M.N., Tashkhodzhaev B., and Silmov B.T. Khim. Prir. Soedin. 33 (1997) 254
13. Henry A. Plant Alkaloids (1966), Churchill, London p 75
14. Pelletier S.W. Chemistry of Alkaloids (1970), Van Nostrand, New York p 503
15. Parthiban P., Aridoss G., Rathika P., Ramkumar V., and Kabilan S. Bioorg. Med. Chem. Lett. 19 (2009) 2981
16. Parthiban P., Balasubramanian S., Aridoss G., and Kabilan S. Med. Chem. Res. 14 (2005) 523
17. Ramalingan C., Park Y.T., and Kabilan S. Eur. J. Med. Chem. 41 (2006) 683
18. Bhandari K., Srinivas N., Kesava G.B.S., and Shukla P.K. Eur. J. Med. Chem. 44 (2009) 437
19. Mixich G., and Thiele K. Arzneim.-Forsch./Drug Res. 29 (1979) 1510
20. Polak A. Arzneim.-Forsch./Drug Res. 32 (1982) 17
21. Rossello A., Bertini S., Lapucci A., Macchia M., Martinelli A., Rapposelli S., Herreros E., and Macchia B. J. Med. Chem. 45 (2002) 4903
22. Emami S., Falahati M., Banifatemi A., Amanlouc M., and Shafiee A. Bioorg. Med. Chem. 12 (2004) 3971
23. Karakurt A., Dalkara S., Ozalp M., Ozbey S., Kendy E., and Stables J.P. Eur. J. Med. Chem. 36 (2001) 421
24. Milanese L., Giacche N., Schiaffella F., Vecchiarelli A., Macchiarulo A., and Fringuelli R. Chem. Med. Chem. 2 (2007) 1208
25. Parthiban P., Rani M., and Kabilan S. Monatsh. Chem. 140 (2009) 287
26. Parthiban P., Balasubramanian S., Aridoss G., and Kabilan S. Spectrochim. Acta Part A 70 (2008) 11
27. Parthiban P., Ramachandran R., Aridoss G., and Kabilan S. Magn. Reson. Chem. 46 (2008) 780
28. Dhar M.L., Dhar M.M., Dhawan B.N., Mehrotra B.N., and Ray C. Indian J. Exp. Biol. 6 (1968) 232