The role of Doppler and placental screening

Best Practice and Research: Clinical Obstetrics and Gynaecology

Volumn 23, Issue 6, 2009, Pages 845-855

  Cruz Martinez, Rogelio ^a,b   Figueras, Francesc ^a,b  

^a HOSPITAL CLÍNIC   (Spain)

^b INSTITUT D INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER IDIBAPS   (Spain)

Author keywords

doppler ultrasound; intrauterine growth restriction; perinatal care; placental diseases; pregnancy complications

Indexed keywords

DEVELOPING COUNTRY; DOPPLER ECHOGRAPHY; DUCTUS VENOSUS; FETUS ACID BASE BALANCE; HEART PERFORMANCE; HIGH RISK POPULATION; HUMAN; INTRAUTERINE GROWTH RETARDATION; PLACENTA; PREDICTION; PREECLAMPSIA; PREGNANCY; PRIORITY JOURNAL; REVIEW; SCREENING; SMALL FOR DATE INFANT; UMBILICAL ARTERY; AORTA; BLOOD FLOW VELOCITY; DOPPLER FLOWMETRY; ECHOGRAPHY; FEMALE; FETUS ECHOGRAPHY; HEART CONTRACTION; MIDDLE CEREBRAL ARTERY; PATHOPHYSIOLOGY; PHYSIOLOGY; PLACENTA DISORDER; PREGNANCY OUTCOME; UTERINE ARTERY;

AORTA; BLOOD FLOW VELOCITY; FEMALE; FETAL GROWTH RETARDATION; HUMANS; MIDDLE CEREBRAL ARTERY; MYOCARDIAL CONTRACTION; PLACENTA DISEASES; PREGNANCY; PREGNANCY OUTCOME; ULTRASONOGRAPHY, DOPPLER; ULTRASONOGRAPHY, PRENATAL; UMBILICAL ARTERIES; UTERINE ARTERY;

EID: 71849089994     PISSN: 15216934     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bpobgyn.2009.08.007     Document Type: Review

References (66)

1. Kady S., and Gardosi J. Perinatal mortality and fetal growth restriction. Best Pract Res Clin Obstet Gynaecol 18 3 (2004) 397-410
2. Spinillo A., Gardella B., Preti E., et al. Rates of neonatal death and cerebral palsy associated with fetal growth restriction among very low birthweight infants. A temporal analysis. BJOG 113 7 (2006) 775-780
3. Clausson B., Cnattingius S., and Axelsson O. Preterm and term births of small for gestational age infants: a population-based study of risk factors among nulliparous women. Br J Obstet Gynaecol 105 9 (1998) 1011-1017
4. Burke G., Stuart B., Crowley P., et al. Is intrauterine growth retardation with normal umbilical artery blood flow a benign condition?. BMJ 300 6731 (1990) 1044-1045
5. Trudinger B.J., Cook C.M., Giles W.B., et al. Fetal umbilical artery velocity waveforms and subsequent neonatal outcome. Br J Obstet Gynaecol 98 4 (1991) 378-384
6. McCowan L.M., Harding J.E., and Stewart A.W. Umbilical artery Doppler studies in small for gestational age babies reflect disease severity. BJOG 107 7 (2000) 916-925
7. Bobrow C.S., and Soothill P.W. Fetal growth velocity: a cautionary tale. Lancet 353 9163 (1999) 1460
8. Soothill P.W., Bobrow C.S., and Holmes R. Small for gestational age is not a diagnosis. Ultrasound Obstet Gynecol 13 4 (1999) 225-228
9. McCowan L.M., Harding J.E., Roberts A.B., et al. A pilot randomized controlled trial of two regimens of fetal surveillance for small-for-gestational-age fetuses with normal results of umbilical artery doppler velocimetry. Am J Obstet Gynecol 182 1 Pt 1 (2000) 81-86
10. Figueras F., Eixarch E., Meler E., et al. Small-for-gestational-age fetuses with normal umbilical artery Doppler have suboptimal perinatal and neurodevelopmental outcome. Eur J Obstet Gynecol Reprod Biol 136 1 (2008) 34-38
11. Severi F.M., Bocchi C., Visentin A., et al. Uterine and fetal cerebral Doppler predict the outcome of third-trimester small-for-gestational age fetuses with normal umbilical artery Doppler. Ultrasound Obstet Gynecol 19 3 (2002) 225-228
12. Figueras F., Oros D., Cruz-Martinez R., et al. Neurobehavioral outcome of full-term small-for-gestational age infants with normal placental function. Pediatrics (2009)
13. Madazli R., Somunkiran A., Calay Z., et al. Histomorphology of the placenta and the placental bed of growth restricted foetuses and correlation with the Doppler velocimetries of the uterine and umbilical arteries. Placenta 24 5 (2003) 510-516
14. Papageorghiou A.T., Yu C.K., Bindra R., et al. Multicenter screening for pre-eclampsia and fetal growth restriction by transvaginal uterine artery Doppler at 23 weeks of gestation. Ultrasound Obstet Gynecol 18 5 (2001) 441-449
15. Martin A.M., Bindra R., Curcio P., et al. Screening for pre-eclampsia and fetal growth restriction by uterine artery Doppler at 11-14 weeks of gestation. Ultrasound Obstet Gynecol 18 6 (2001) 583-586
16. Onwudiwe N., Yu C.K., Poon L.C., et al. Prediction of pre-eclampsia by a combination of maternal history, uterine artery Doppler and mean arterial pressure. Ultrasound Obstet Gynecol 32 7 (2008) 877-883
17. Spencer K., Cowans N.J., and Nicolaides K.H. Maternal serum inhibin-A and activin-A levels in the first trimester of pregnancies developing pre-eclampsia. Ultrasound Obstet Gynecol 32 5 (2008) 622-626
18. Crispi F., Llurba E., Dominguez C., et al. Predictive value of angiogenic factors and uterine artery Doppler for early- versus late-onset pre-eclampsia and intrauterine growth restriction. Ultrasound Obstet Gynecol 31 3 (2008) 303-309
19. Smith G.C., Crossley J.A., Aitken D.A., et al. Circulating angiogenic factors in early pregnancy and the risk of preeclampsia, intrauterine growth restriction, spontaneous preterm birth, and stillbirth. Obstet Gynecol 109 6 (2007) 1316-1324
20. Chafetz I., Kuhnreich I., Sammar M., et al. First-trimester placental protein 13 screening for preeclampsia and intrauterine growth restriction. Am J Obstet Gynecol 197 1 (2007) 35.e1-35.e7
21. Romero R., Kusanovic J.P., Than N.G., et al. First-trimester maternal serum PP13 in the risk assessment for preeclampsia. Am J Obstet Gynecol 199 2 (2008) 122.e1-122.e11
22. Vergani P., Roncaglia N., Andreotti C., et al. Prognostic value of uterine artery Doppler velocimetry in growth-restricted fetuses delivered near term. Am J Obstet Gynecol 187 4 (2002) 932-936
23. Chien P.F., Arnott N., Gordon A., et al. How useful is uterine artery Doppler flow velocimetry in the prediction of pre-eclampsia, intrauterine growth retardation and perinatal death? An overview. BJOG 107 2 (2000) 196-208
24. Sebire N.J. Umbilical artery Doppler revisited: pathophysiology of changes in intrauterine growth restriction revealed. Ultrasound Obstet Gynecol 21 5 (2003) 419-422
25. Nicolaides K.H., Bilardo C.M., Soothill P.W., et al. Absence of end diastolic frequencies in umbilical artery: a sign of fetal hypoxia and acidosis. BMJ 297 6655 (1988) 1026-1027
26. Karsdorp V.H., van Vugt J.M., Jakobs C., et al. Amino acids, glucose and lactate concentrations in umbilical cord blood in relation to umbilical artery flow patterns. Eur J Obstet Gynecol Reprod Biol 57 2 (1994) 117-122
27. James D.K., Parker M.J., and Smoleniec J.S. Comprehensive fetal assessment with three ultrasonographic characteristics. Am J Obstet Gynecol 166 5 (1992) 1486-1495
28. McCowan L.M., Harding J.E., and Stewart A.W. Customized birthweight centiles predict SGA pregnancies with perinatal morbidity. BJOG 112 8 (2005) 1026-1033
29. Chang T.C., Robson S.C., Spencer J.A., et al. Prediction of perinatal morbidity at term in small fetuses: comparison of fetal growth and Doppler ultrasound. Br J Obstet Gynaecol 101 5 (1994) 422-427
30. Gaziano E.P., Knox H., Ferrera B., et al. Is it time to reassess the risk for the growth-retarded fetus with normal Doppler velocimetry of the umbilical artery?. Am J Obstet Gynecol 170 6 (1994) 1734-1741 discussion 1741-3
31. Reuwer P.J., Sijmons E.A., Rietman G.W., et al. Intrauterine growth retardation: prediction of perinatal distress by Doppler ultrasound. Lancet 2 8556 (1987) 415-418
32. Yoon B.H., Lee C.M., and Kim S.W. An abnormal umbilical artery waveform: a strong and independent predictor of adverse perinatal outcome in patients with preeclampsia. Am J Obstet Gynecol 171 3 (1994) 713-721
33. Hecher K., Bilardo C.M., Stigter R.H., et al. Monitoring of fetuses with intrauterine growth restriction: a longitudinal study. Ultrasound Obstet Gynecol 18 6 (2001) 564-570
34. Mandruzzato G.P., Bogatti P., Fischer L., et al. The clinical significance of absent or reverse end-diastolic flow in the fetal aorta and umbilical artery. Ultrasound Obstet Gynecol 1 3 (1991) 192-196
35. Cosmi E., Ambrosini G., D'Antona D., et al. Doppler, cardiotocography, and biophysical profile changes in growth-restricted fetuses. Obstet Gynecol 106 6 (2005) 1240-1245
36. Valcamonico A., Danti L., Frusca T., et al. Absent end-diastolic velocity in umbilical artery: risk of neonatal morbidity and brain damage. Am J Obstet Gynecol 170 3 (1994) 796-801
37. Neilson J.P., and Alfirevic Z. Doppler ultrasound for fetal assessment in high risk pregnancies. Cochrane Database Syst Rev (2000) (2):CD000073
38. Thornton J.G., Hornbuckle J., Vail A., et al. Infant wellbeing at 2 years of age in the Growth Restriction Intervention Trial (GRIT): multicentred randomised controlled trial. Lancet 364 9433 (2004) 513-520
39. Baschat A.A., Gembruch U., and Harman C.R. The sequence of changes in Doppler and biophysical parameters as severe fetal growth restriction worsens. Ultrasound Obstet Gynecol 18 6 (2001) 571-577
40. Ferrazzi E., Bozzo M., Rigano S., et al. Temporal sequence of abnormal Doppler changes in the peripheral and central circulatory systems of the severely growth-restricted fetus. Ultrasound Obstet Gynecol 19 2 (2002) 140-146
41. Bahado-Singh R.O., Kovanci E., Jeffres A., et al. The Doppler cerebroplacental ratio and perinatal outcome in intrauterine growth restriction. Am J Obstet Gynecol 180 3 Pt 1 (1999) 750-756
42. Odibo A.O., Riddick C., Pare E., et al. Cerebroplacental Doppler ratio and adverse perinatal outcomes in intrauterine growth restriction: evaluating the impact of using gestational age-specific reference values. J Ultrasound Med 24 9 (2005) 1223-1228
43. Hershkovitz R., Kingdom J.C., Geary M., et al. Fetal cerebral blood flow redistribution in late gestation: identification of compromise in small fetuses with normal umbilical artery Doppler. Ultrasound Obstet Gynecol 15 3 (2000) 209-212
44. To W.W., Chan A.M., and Mok K.M. Use of umbilical-cerebral Doppler ratios in predicting fetal growth restriction in near-term fetuses. Aust N Z J Obstet Gynaecol 45 2 (2005) 130-136
45. Scherjon S.A., Oosting H., Smolders-DeHaas H., et al. Neurodevelopmental outcome at three years of age after fetal 'brain-sparing'. Early Hum Dev 52 1 (1998) 67-79
46. Cruz-Martinez R., Figueras F., Oros D., et al. Cerebral blood perfusion and neurobehavioral performance in full-term small-for-gestational-age fetuses. Am J Obstet Gynecol (2009)
47. Oros D., Figueras F., Cruz-Martinez R., et al. Anterior cerebral artery vasodilation correlation with the neurological evaluation of growth restricted neonates. Ultrasound Obstet Gynecol (2009)
48. Eixarch E., Meler E., Iraola A., et al. Neurodevelopmental outcome in 2-year-old infants who were small-for-gestational age term fetuses with cerebral blood flow redistribution. Ultrasound Obstet Gynecol 32 7 (2008) 894-899
49. Scherjon S., Briet J., Oosting H., et al. The discrepancy between maturation of visual-evoked potentials and cognitive outcome at five years in very preterm infants with and without hemodynamic signs of fetal brain-sparing. Pediatrics 105 2 (2000) 385-391
50. Kok J.H., Prick L., Merckel E., et al. Visual function at 11 years of age in preterm-born children with and without fetal brain sparing. Pediatrics 119 6 (2007) e1342-e1350
51. Gramellini D., Folli M.C., Raboni S., et al. Cerebral-umbilical Doppler ratio as a predictor of adverse perinatal outcome. Obstet Gynecol 79 3 (1992) 416-420
52. Arbeille P., Maulik D., Fignon A., et al. Assessment of the fetal PO2 changes by cerebral and umbilical Doppler on lamb fetuses during acute hypoxia. Ultrasound Med Biol 21 7 (1995) 861-870
53. Makhseed M., Jirous M., Ahmed M.A., et al. Middle cerebral artery to umbilical artery resistance index ratio in the prediction of neonatal outcome. Int J Gynaecol Obstet 71 2 (2000) 119-125
54. Hecher K., Snijders R., Campbell S., et al. Fetal venous, intracardiac, and arterial blood flow measurements in intrauterine growth retardation: relationship with fetal blood gases. Am J Obstet Gynecol 173 1 (1995) 10-15
55. Schwarze A., Gembruch U., Krapp M., et al. Qualitative venous Doppler flow waveform analysis in preterm intrauterine growth-restricted fetuses with ARED flow in the umbilical artery-correlation with short-term outcome. Ultrasound Obstet Gynecol 25 6 (2005) 573-579
56. Baschat A.A., Gembruch U., Weiner C.P., et al. Qualitative venous Doppler waveform analysis improves prediction of critical perinatal outcomes in premature growth-restricted fetuses. Ultrasound Obstet Gynecol 22 3 (2003) 240-245
57. Baschat A.A., Cosmi E., Bilardo C.M., et al. Predictors of neonatal outcome in early-onset placental dysfunction. Obstet Gynecol 109 2 Pt 1 (2007) 253-261
58. Bilardo C.M., Wolf H., Stigter R.H., et al. Relationship between monitoring parameters and perinatal outcome in severe, early intrauterine growth restriction. Ultrasound Obstet Gynecol 23 2 (2004) 119-125
59. Baschat A.A., Galan H.L., Bhide A., et al. Doppler and biophysical assessment in growth restricted fetuses: distribution of test results. Ultrasound Obstet Gynecol 27 1 (2006) 41-47
60. Fouron J.C. The unrecognized physiological and clinical significance of the fetal aortic isthmus. Ultrasound Obstet Gynecol 22 5 (2003) 441-447
61. Fouron J.C., Skoll A., Sonesson S.E., et al. Relationship between flow through the fetal aortic isthmus and cerebral oxygenation during acute placental circulatory insufficiency in ovine fetuses. Am J Obstet Gynecol 181 5 Pt 1 (1999) 1102-1107
62. Makikallio K., Jouppila P., and Rasanen J. Retrograde aortic isthmus net blood flow and human fetal cardiac function in placental insufficiency. Ultrasound Obstet Gynecol 22 4 (2003) 351-357
63. Del Rio M., Martinez J.M., Figueras F., et al. Doppler assessment of the aortic isthmus and perinatal outcome in preterm fetuses with severe intrauterine growth restriction. Ultrasound Obstet Gynecol 31 1 (2008) 41-47
64. Fouron J.C., Gosselin J., Raboisson M.J., et al. The relationship between an aortic isthmus blood flow velocity index and the postnatal neurodevelopmental status of fetuses with placental circulatory insufficiency. Am J Obstet Gynecol 192 2 (2005) 497-503
65. Crispi F., Hernandez-Andrade E., Pelsers M.M., et al. Cardiac dysfunction and cell damage across clinical stages of severity in growth-restricted fetuses. Am J Obstet Gynecol 199 3 (2008) 254.e1-254.e8
66. Hernandez-Andrade E, Crispi F, Benavides-Serralde A, et al. Contribution of the modified myocardial performance index and aortic isthmus blood flow index to refine prediction of mortality in preterm intrauterine growth restricted fetuses. Ultrasound Obstet Gynecol 2009.