Prolactin induces Egr-1 gene expression in cultured hypothalamic cells and in the rat hypothalamus

Brain Research

Volumn 1302, Issue , 2009, Pages 34-41

  Blume, Annegret ^a   Torner, Luz ^a,b   Liu, Ying ^c   Subburaju, Sivan ^c   Aguilera, Greti ^c   Neumann, Inga D ^a  

^a UNIVERSITY OF REGENSBURG   (Germany)

^b INSTITUTO MEXICANO DEL SEGURO SOCIAL   (Mexico)

^c EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

Hypothalamo pituitary adrenal axis; Lactation; Neuroplasticity; Signaling; Stress; Transcription factor

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; EARLY GROWTH RESPONSE FACTOR 1; MESSENGER RNA; PROLACTIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; HYPOTHALAMUS; IMMUNOHISTOCHEMISTRY; NERVE CELL; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; SIGNAL TRANSDUCTION; SUPRAOPTIC NUCLEUS; THALAMUS MIDLINE NUCLEUS;

ANIMALS; CELLS, CULTURED; CORTICOTROPIN-RELEASING HORMONE; EARLY GROWTH RESPONSE PROTEIN 1; ENZYME INHIBITORS; FEMALE; GENE EXPRESSION; HYPOTHALAMUS; IMMUNOHISTOCHEMISTRY; MAP KINASE SIGNALING SYSTEM; NEURONAL PLASTICITY; NEURONS; OXYTOCIN; PARAVENTRICULAR HYPOTHALAMIC NUCLEUS; PROLACTIN; RATS; RATS, WISTAR; RNA, MESSENGER; SUPRAOPTIC NUCLEUS;

RATTUS;

EID: 71849086377     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2009.09.047     Document Type: Article

References (48)

1. Bakowska J.C., and Morrell J.I. Atlas of the neurons that express mRNA for the long form of the prolactin receptor in the forebrain of the female rat. J. Comp. Neurol. 386 (1997) 161-177
2. Bakowska J.C., and Morrell J.I. The distribution of mRNA for the short form of the prolactin receptor in the forebrain of the female rat. Brain Res. Mol. Brain Res. 116 (2003) 50-58
3. Beckmann A.M., and Wilce P.A. Egr transcription factors in the nervous system. Neurochem. Int. 31 (1997) 477-510 discussion 517-6
4. Ben-Jonathan N., Mershon J., Allen D., and Steinmetz R. Extrapituitary prolactin: distribution, regulation, functions, and clinical aspects. Endocr. Rev. 17 (1996) 639-669
5. Blume A., Lebrun C.J., Herdegen T., Bravo R., Linz W., Mollenhoff E., and Unger T. Increased brain transcription factor expression by angiotensin in genetic hypertension. Hypertension 29 (1997) 592-598
6. Blume A., Torner L., Liu Y., Subburaju S., Aguilera G., and Neumann I.D. Prolactin activates mitogen-activated protein kinase signaling and corticotropin releasing hormone transcription in rat hypothalamic neurons. Endocrinology 150 (2009) 1841-1849
7. Bole-Feysot C., Perret E., Roustan P., Bouchard B., and Kelly P.A. Analysis of prolactin-modulated gene expression profiles during the Nb2 cell cycle using differential screening techniques. Genome. Biol. 1 (2000) RESEARCH0008
8. Bosch O.J., Kromer S.A., and Neumann I.D. Prenatal stress: opposite effects on anxiety and hypothalamic expression of vasopressin and corticotropin-releasing hormone in rats selectively bred for high and low anxiety. Eur. J. Neurosci. 23 (2006) 541-551
9. Chiu S., and Wise P. Prolactin receptor mRNA localization in the hypothalamus by in situ hybridization. J. Neuroendocrinol. 6 (1994) 191-199
10. Clapp C., Torner L., Gutierrez-Ospina G., Alcantara E., Lopez-Gomez F., Nagano M., Kelly P., Mejia S., MA M., and Martinez de la Escalera G. The prolactin gene is expressed in the hypothalamic-neurohypophyseal system and the protein is processed into a 14-kDa fragment with activity like 16-kDa prolactin. Proc. Natl. Acad. Sci. U. S. A. 91 (1994) 10384-10388
11. Emanuele N., Jurgens J., Halloran M., Tentler J., Lawrence A., and Kelley M. The rat prolactin gene is expressed in brain tissue: detection of normal and alternatively spliced prolactin messenger RNA. Mol. Endocrinol. 6 (1992) 35-42
12. Goldhar A.S., Vonderhaar B.K., Trott J.F., and Hovey R.C. Prolactin-induced expression of vascular endothelial growth factor via Egr-1. Mol. Cell. Endocrinol. 232 (2005) 9-19
13. Gregg C., Shikar V., Larsen P., Mak G., Chojnacki A., Yong V.W., and Weiss S. White matter plasticity and enhanced remyelination in the maternal CNS. J. Neurosci. 27 (2007) 1812-1823
14. Harada T., Morooka T., Ogawa S., and Nishida E. ERK induces p35, a neuron-specific activator of Cdk5, through induction of Egr1. Nat. Cell. Biol. 3 (2001) 453-459
15. Hatton G.I. Dynamic neuronal-glial interactions: an overview 20 years later. Peptides 25 (2004) 403-411
16. Herdegen T., and Leah J.D. Inducible and constitutive transcription factors in the mammalian nervous system: control of gene expression by Jun, Fos and Krox, and CREB/ATF proteins. Brain Res. Brain Res. Rev. 28 (1998) 370-490
17. Herdegen T., Walker T., Leah J.D., Bravo R., and Zimmermann M. The KROX-24 protein, a new transcription regulating factor: expression in the rat central nervous system following afferent somatosensory stimulation. Neurosci. Lett. 120 (1990) 21-24
18. James A.B., Conway A.M., and Morris B.J. Regulation of the neuronal proteasome by Zif268 (Egr1). J. Neurosci. 26 (2006) 1624-1634
19. Jones M.W., Errington M.L., French P.J., Fine A., Bliss T.V., Garel S., Charnay P., Bozon B., Laroche S., and Davis S. A requirement for the immediate early gene Zif268 in the expression of late LTP and long-term memories. Nat. Neurosci. 4 (2001) 289-296
20. Kasckow J., Mulchahey J.J., Aguilera G., Pisarska M., Nikodemova M., Chen H.C., Herman J.P., Murphy E.K., Liu Y., Rizvi T.A., Dautzenberg F.M., and Sheriff S. Corticotropin-releasing hormone (CRH) expression and protein kinase A mediated CRH receptor signalling in an immortalized hypothalamic cell line. J. Neuroendocrinol. 15 (2003) 521-529
21. Khachigian L.M., Williams A.J., and Collins T. Interplay of Sp1 and Egr-1 in the proximal platelet-derived growth factor A-chain promoter in cultured vascular endothelial cells. J. Biol. Chem. 270 (1995) 27679-27686
22. Khachigian L.M., Lindner V., Williams A.J., and Collins T. Egr-1-induced endothelial gene expression: a common theme in vascular injury. Science 271 (1996) 1427-1431
23. Kokay I.C., Bull P.M., Davis R.L., Ludwig M., and Grattan D.R. Expression of the long form of the prolactin receptor in magnocellular oxytocin neurons is associated with specific prolactin regulation of oxytocin neurons. Am. J. Physiol. Regul. Integr. Comp. Physiol. 290 (2006) R1216-1225
24. Langle S.L., Poulain D.A., and Theodosis D.T. Induction of rapid, activity-dependent neuronal-glial remodelling in the adult rat hypothalamus in vitro. Eur. J. Neurosci. 18 (2003) 206-214
25. Lee S.L., Sadovsky Y., Swirnoff A.H., Polish J.A., Goda P., Gavrilina G., and Milbrandt J. Luteinizing hormone deficiency and female infertility in mice lacking the transcription factor NGFI-A (Egr-1). Science 273 (1996) 1219-1221
26. Li L., Carter J., Gao X., Whitehead J., and Tourtellotte W.G. The neuroplasticity-associated arc gene is a direct transcriptional target of early growth response (Egr) transcription factors. Mol. Cell. Biol. 25 (2005) 10286-10300
27. Livak K.J., and Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25 (2001) 402-408
28. Mack K., Day M., Milbrandt J., and Gottlieb D.I. Localization of the NGFI-A protein in the rat brain. Brain Res. Mol. Brain Res. 8 (1990) 177-180
29. Mak G.K., Enwere E.K., Gregg C., Pakarainen T., Poutanen M., Huhtaniemi I., and Weiss S. Male pheromone-stimulated neurogenesis in the adult female brain: possible role in mating behavior. Nat. Neurosci. 10 (2007) 1003-1011
30. Mangurian L.P., Walsh R.J., and Posner B.I. Prolactin enhancement of its own uptake at the choroid plexus. Endocrinology 131 (1992) 698-702
31. Mejia S., Torner L., Jeziorski M., Gonzalez C., Morales M., de la Escalera G., and Clapp C. Prolactin and 16K prolactin stimulate release of vasopressin by a direct effect on hypothalamo-neurohypophyseal system. Endocrine 20 (2003) 155-162
32. Nagano M., and Kelly P. Tissue distribution and regulation of rat prolactin receptor gene expression: quantitative analysis by polymerase chain reaction. J. Biol. Chem. 269 (1994) 13337-13345
33. Neumann I.D., Torner L., and Wigger A. Brain oxytocin: differential inhibition of neuroendocrine stress responses and anxiety-related behaviour in virgin, pregnant and lactating rats. Neuroscience 95 (2000) 567-575
34. Nikam S.S., Tennekoon G.I., Christy B.A., Yoshino J.E., and Rutkowski J.L. The zinc finger transcription factor Zif268/Egr-1 is essential for Schwann cell expression of the p75 NGF receptor. Mol. Cell. Neurosci. 6 (1995) 337-348
35. O'Donovan K.J., Tourtellotte W.G., Millbrandt J., and Baraban J.M. The EGR family of transcription-regulatory factors: progress at the interface of molecular and systems neuroscience. Trends Neurosci. 22 (1999) 167-173
36. Rho J.H., and Swanson L.W. A morphometric analysis of functionally defined subpopulations of neurons in the paraventricular nucleus of the rat with observations on the effects of colchicine. J. Neurosci. 9 (1989) 1375-1388
37. Sagrillo C.A., and Selmanoff M. Effects of prolactin on expression of the mRNAs encoding the immediate early genes zif/268 (NGF1-A), nur/77 (NGF1-B), c-fos and c-jun in the hypothalamus. Brain Res. Mol. Brain Res. 61 (1998) 62-68
38. Schlingensiepen K.H., Luno K., and Brysch W. High basal expression of the zif/268 immediate early gene in cortical layers IV and VI, in CA1 and in the corpus striatum-an in situ hybridization study. Neurosci. Lett. 122 (1991) 67-70
39. Shingo T., Gregg C., Enwere E., Fujikawa H., Hassam R., Geary C., Cross J.C., and Weiss S. Pregnancy-stimulated neurogenesis in the adult female forebrain mediated by prolactin. Science 299 (2003) 117-120
40. Svaren J., Ehrig T., Abdulkadir S.A., Ehrengruber M.U., Watson M.A., and Milbrandt J. EGR1 target genes in prostate carcinoma cells identified by microarray analysis. J. Biol. Chem. 275 (2000) 38524-38531
41. Theodosis D.T., Montagnese C., Rodriguez F., Vincent J.D., and Poulain D.A. Oxytocin induces morphological plasticity in the adult hypothalamo-neurohypophysial system. Nature 322 (1986) 738-740
42. Thiel G., Schoch S., and Petersohn D. Regulation of synapsin I gene expression by the zinc finger transcription factor zif268/egr-1. J. Biol. Chem. 269 (1994) 15294-15301
43. Torner L., Maloumby R., Nava G., Aranda J., Clapp C., and Neumann I.D. In vivo release and gene upregulation of brain prolactin in response to physiological stimuli. Eur. J. Neurosci. 19 (2004) 1601-1608
44. Torner L., Karg S., Blume A., Kandasamy M., Kuhn H.G., Winkler J., Aigner L., and Neumann I.D. Prolactin prevents chronic stress-induced decrease of adult hippocampal neurogenesis and promotes neuronal fate. J. Neurosci. 29 (2009) 1826-1833
45. Toubeau G., Desclin J., Parmentier M., and Pasteels J. Cellular localization of a prolactin-like antigen in the rat brain. J. Endocrinol. 83 (1979) 261-266
46. Walsh R., Slaby F., and Posner B. A receptor-mediated mechanism for the transport of prolactin from blood to cerebrospinal fluid. Endocrinology 120 (1987) 1846-1850
47. Waters C.M., Hancock D.C., and Evan G.I. Identification and characterisation of the egr-1 gene product as an inducible, short-lived, nuclear phosphoprotein. Oncogene 5 (1990) 669-674
48. Wong D.L., Tai T.C., Wong-Faull D.C., Claycomb R., and Kvetnansky R. Genetic mechanisms for adrenergic control during stress. Ann. N.Y. Acad. Sci. 1018 (2004) 387-397