Multiple, independent, identical IS6110 insertions in Mycobacterium tuberculosis PPE genes

Tuberculosis

Volumn 89, Issue 6, 2009, Pages 439-442

  McEvoy, Christopher R E ^a   Warren, Robin M ^a   van Helden, Paul D ^a   Gey van Pittius, Nicolaas C ^a  

^a SOUTH AFRICAN MEDICAL RESEARCH COUNCIL   (South Africa)

Author keywords

IS6110; IS6110 insertion sequence; PPE; PPE family; Transposable elements

Indexed keywords

ARTICLE; BACTERIAL GENOME; GENE INSERTION; GENETIC VARIABILITY; MYCOBACTERIUM TUBERCULOSIS; PPE GENE; PRIORITY JOURNAL; TRANSPOSON;

ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; BASE SEQUENCE; DNA TRANSPOSABLE ELEMENTS; DNA, BACTERIAL; HUMANS; MUTAGENESIS, INSERTIONAL; MYCOBACTERIUM TUBERCULOSIS; SEQUENCE ANALYSIS, DNA;

EID: 71849083391     PISSN: 14729792     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tube.2009.08.001     Document Type: Article

References (12)

1. van Embden J.D., Cave M.D., Crawford J.T., Dale J.W., Eisenach K.D., Gicquel B., et al. Strain identification of Mycobacterium tuberculosis by DNA fingerprinting: recommendations for a standardized methodology. J Clin Microbiol 31 (1993) 406-409
2. Sampson S.L., Warren R.M., Richardson M., van der Spuy G.D., and van Helden P.D. Disruption of coding regions by IS 6110 insertion in Mycobacterium tuberculosis. Tuber Lung Dis 79 (1999) 349-359
3. Warren R.M., Sampson S.L., Richardson M., van der Spuy G.D., Lombard C.J., Victor T.C., et al. Mapping of IS 6110 flanking regions in clinical isolates of Mycobacterium tuberculosis demonstrates genome plasticity. Mol Microbiol 37 (2000) 1405-1416
4. Yesilkaya H., Dale J.W., Strachan N.J., and Forbes K.J. Natural transposon mutagenesis of clinical isolates of Mycobacterium tuberculosis: how many genes does a pathogen need?. J Bacteriol 187 (2005) 6726-6732
5. Warren R.M., Richardson M., Sampson S.L., van der Spuy G.D., Bourn W., Hauman J.H., et al. Molecular evolution of Mycobacterium tuberculosis: phylogenetic reconstruction of clonal expansion. Tuberculosis 81 (2001) 291-302
6. Warren R.M., Victor T.C., Streicher E.M., Richardson M., van der Spuy G.D., Johnson R., et al. Clonal expansion of a globally disseminated lineage of Mycobacterium tuberculosis with low IS 6110 copy numbers. J Clin Microbiol 42 (2004) 5774-5782
7. Hershberg R., Lipatov M., Small P.M., Sheffer H., Niemann S., Homolka S., et al. High functional diversity in Mycobacterium tuberculosis driven by genetic drift and human demography. PloS Biology 6 (2008) 2658-2671
8. Brosch R., Gordon S.V., Marmiesse M., Brodin P., Buchrieser C., Eiglmeier K., et al. A new evolutionary scenario for the Mycobacterium tuberculosis complex. Proc Natl Acad Sci USA 99 (2002) 3684-3689
9. McHugh T.D., and Gillespie S.H. Nonrandom association of IS 6110 and Mycobacterium tuberculosis: implications for molecular epidemiological studies. J Clin Microbiol 36 (1998) 1410-1413
10. Gillespie S.H., Dickens A., and McHugh T.D. False molecular clusters due to nonrandom association of IS 6110 with Mycobacterium tuberculosis. J Clin Microbiol 38 (2000) 2081-2086
11. Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C., Harris D., et al. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature 393 (1998) 537-544
12. Zheng H., Lu L., Wang B., Pu S., Zhang X., Zhu G., et al. Genetic basis of virulence attenuation revealed by comparative genomic analysis of Mycobacterium tuberculosis strain H37Ra versus H37Rv. PLoS ONE 3 (2008) e2375