Association Between Serum γ-Glutamyltransferase and Acute Ischemic Nonembolic Stroke in Elderly Subjects

Archives of Medical Research

Volumn 40, Issue 7, 2009, Pages 582-589

  Korantzopoulos, Panagiotis ^a   Tzimas, Petros ^a   Kalantzi, Kallirroi ^a   Kostapanos, Michael ^a   Vemmos, Konstantinos ^b   Goudevenos, John ^a   Elisaf, Moses ^a   Milionis, Haralampos ^a  

^a UNIVERSITY OF IOANNINA   (Greece)

^b UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

Author keywords

Glutamyltransferase; Elderly; Insulin resistance; Ischemic stroke; Metabolic syndrome; Stroke risk

Indexed keywords

APOLIPOPROTEIN A1; APOLIPOPROTEIN B; CHOLESTEROL; GAMMA GLUTAMYLTRANSFERASE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIPOPROTEIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

AGED; ARTICLE; BODY MASS; CARDIOVASCULAR RISK; CASE CONTROL STUDY; CEREBROVASCULAR ACCIDENT; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; ELDERLY CARE; FEMALE; GAMMA GLUTAMYL TRANSFERASE BLOOD LEVEL; HUMAN; INSULIN RESISTANCE; LIPOPROTEIN BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; METABOLIC SYNDROME X; RISK FACTOR;

AGED; AGED, 80 AND OVER; BRAIN ISCHEMIA; CASE-CONTROL STUDIES; FEMALE; GAMMA-GLUTAMYLTRANSFERASE; GREECE; HUMANS; MALE; ODDS RATIO; STROKE;

EID: 71649113398     PISSN: 01884409     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.arcmed.2009.07.012     Document Type: Article

References (33)

1. Elkind M.S. Stroke in the elderly. Mt Sinai J Med 70 (2003) 27-37
2. Bonita R. Epidemiology of stroke. Lancet 339 (1992) 342-344
3. Buckley B.M. Healthy ageing: ageing safely. Eur Heart J 3 suppl N (2001) N6-10
4. Emdin M., Passino C., Pompella A., and Paolicchi A. Gamma-glutamyltransferase as a cardiovascular risk factor. Eur Heart J 27 (2006) 2145-2146
5. Grundy S.M. Gamma-glutamyl transferase: another biomarker for metabolic syndrome and cardiovascular risk. Arterioscler Thromb Vasc Biol 27 (2007) 4-7
6. Emdin M., Pompella A., and Paolicchi A. Gamma-glutamyltransferase, atherosclerosis, and cardiovascular disease: triggering oxidative stress within the plaque. Circulation 112 (2005) 2078-2080
7. Franzini M., Corti A., Martinelli B., et al. Gamma-glutamyltransferase activity in human atherosclerotic plaques: biochemical similarities with the circulating enzyme. Atherosclerosis 395 (2008) 188-199
8. Lee D.H., Buijsse B., Steffen L., et al. Association between serum gamma-glutamyltransferase and cardiovascular mortality varies by age: the Minnesota Heart Survey. Eur J Cardiovasc Prev Rehabil 16 (2009) 16-20
9. Strasak A.M., Kelleher C.C., Klenk J., et al. Longitudinal change in serum gamma-glutamyltransferase and cardiovascular disease mortality: a prospective population-based study in 76,113 Austrian adults. Arterioscler Thromb Vasc Biol 28 (2008) 1857-1865
10. Milionis H.J., Liberopoulos E., Goudevenos J., et al. Risk factors for first-ever acute ischemic non-embolic stroke in elderly individuals. Int J Cardiol 99 (2005) 269-275
11. Milionis H.J., Rizos E., Goudevenos J.S., et al. Components of the metabolic syndrome and risk for first-ever acute ischemic nonembolic stroke in elderly subjects. Stroke 36 (2005) 1372-1376
12. Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III). JAMA 285 (2001) 2486-2497
13. Matthews D.R., Hosker J.P., Rudenski A.S., et al. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28 (1985) 412-419
14. Pompella A., Emdin M., Passino C., et al. The significance of serum gamma-glutamyltransferase in cardiovascular diseases. Clin Chem Lab Med 42 (2004) 1085-1091
15. Lee D.H., Blomhoff R., and Jacobs Jr. D.R. Is serum gamma glutamyltransferase a marker of oxidative stress?. Free Radic Res 38 (2004) 535-539
16. Lim J.S., Yang J.H., Chun B.Y., et al. Is serum gamma-glutamyltransferase inversely associated with serum antioxidants as a marker of oxidative stress?. Free Radic Biol Med 37 (2004) 1018-1023
17. Lee D.H., Steffen L.M., and Jacobs Jr. D.R. Association between serum gamma-glutamyltransferase and dietary factors: the Coronary Artery Risk Development in Young Adults (CARDIA) Study. Am J Clin Nutr 79 (2004) 600-605
18. Frey A., Meckelein B., Weiler-Guttler H., et al. Pericytes of the brain microvasculature express gamma-glutamyl transpeptidase. Eur J Biochem 202 (1991) 421-429
19. Bots M.L., Salonen J.T., Elwood P.C., et al. Gamma-glutamyltransferase and risk of stroke: the EUROSTROKE project. J Epidemiol Community Health 56 Suppl. 1 (2002) i25-29
20. Ebrahim S., Sung J., Song Y.M., et al. Serum cholesterol, haemorrhagic stroke, ischaemic stroke, and myocardial infarction: Korean national health system prospective cohort study. BMJ 333 (2006) 22
21. Emdin M., Passino C., Michelassi C., et al. Prognostic value of serum gamma-glutamyl transferase activity after myocardial infarction. Eur Heart J 22 (2001) 1802-1807
22. Fraser A., Harris R., Sattar N., et al. Gamma-glutamyltransferase is associated with incident vascular events independently of alcohol intake: analysis of the British Women's Heart and Health Study and Meta-Analysis. Arterioscler Thromb Vasc Biol 27 (2007) 2729-2735
23. Hozawa A., Okamura T., Kadowaki T., et al. Gamma-glutamyltransferase predicts cardiovascular death among Japanese women. Atherosclerosis 194 (2007) 498-504
24. Jousilahti P., Rastenyte D., and Tuomilehto J. Serum gamma-glutamyl transferase, self-reported alcohol drinking, and the risk of stroke. Stroke 31 (2000) 1851-1855
25. Lee D.H., Jacobs Jr. D.R., Gross M., et al. Gamma-glutamyltransferase is a predictor of incident diabetes and hypertension: the Coronary Artery Risk Development in Young Adults (CARDIA) Study. Clin Chem 49 (2003) 1358-1366
26. Lee D.H., Silventoinen K., Hu G., et al. Serum gamma-glutamyltransferase predicts non-fatal myocardial infarction and fatal coronary heart disease among 28,838 middle-aged men and women. Eur Heart J 27 (2006) 2170-2176
27. Ruttmann E., Brant L.J., Concin H., et al. Gamma-glutamyltransferase as a risk factor for cardiovascular disease mortality: an epidemiological investigation in a cohort of 163,944 Austrian adults. Circulation 112 (2005) 2130-2137
28. Wannamethee S.G., Lennon L., and Shaper A.G. The value of gamma-glutamyltransferase in cardiovascular risk prediction in men without diagnosed cardiovascular disease or diabetes. Atherosclerosis 210 (2008) 168-175
29. Lee D.S., Evans J.C., Robins S.J., et al. Gamma glutamyl transferase and metabolic syndrome, cardiovascular disease, and mortality risk: the Framingham Heart Study. Arterioscler Thromb Vasc Biol 27 (2007) 127-133
30. Lee M.Y., Koh S.B., Koh J.H., et al. Relationship between gamma-glutamyltransferase and metabolic syndrome in a Korean population. Diabet Med 25 (2008) 469-475
31. Lippi G., Targher G., Montagnana M., et al. Relationship between gamma-glutamyltransferase, lipids and lipoprotein(a) in the general population. Clin Chim Acta 384 (2007) 163-166
32. Sakuta H., Suzuki T., Yasuda H., et al. Gamma-glutamyl transferase and metabolic risk factors for cardiovascular disease. Intern Med 44 (2005) 538-541
33. Shankar A., and Li J. Association between serum gamma-glutamyltransferase level and prehypertension among US adults. Circ J 71 (2007) 1567-1572