Intensify, resuscitate or palliate: Decision making in the critically ill patient with haematological malignancy

Blood Reviews

Volumn 24, Issue 1, 2010, Pages 17-25

  Hill, Quentin A ^a  

^a LEEDS TEACHING HOSPITALS NHS TRUST   (United Kingdom)

Author keywords

Cancer; CPR; Haematological malignancy; Intensive care; Resuscitation; Survival

Indexed keywords

ANTINEOPLASTIC AGENT;

ARTICLE; CANCER SURVIVAL; CRITICALLY ILL PATIENT; DISEASE SEVERITY; GENERAL CONDITION DETERIORATION; HEMATOLOGIC MALIGNANCY; HOSPITAL ADMISSION; HOSPITAL DISCHARGE; HUMAN; INTENSIVE CARE; LIFE SUSTAINING TREATMENT; MEDICAL DECISION MAKING; OVERALL SURVIVAL; PALLIATIVE THERAPY; PHYSICAL PERFORMANCE; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; RESUSCITATION; STEM CELL TRANSPLANTATION; THERAPY EFFECT; TREATMENT OUTCOME;

CARDIOPULMONARY RESUSCITATION; CRITICAL ILLNESS; DECISION MAKING; HEMATOLOGIC NEOPLASMS; HUMANS; INFORMED CONSENT; INTENSIVE CARE UNITS; PALLIATIVE CARE; PROGNOSIS;

EID: 71649102462     PISSN: 0268960X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.blre.2009.10.002     Document Type: Article

References (133)

1. Goldhill D.R., White S.A., and Sumner A. Physiological values and procedures in the 24 h before ICU admission from the ward. Anaesthesia 54 6 (1999) 529-534
2. Smith G.B., Prytherch D.R., Schmidt P.E., and Featherstone P.I. Review and performance evaluation of aggregate weighted 'track and trigger' systems. Resuscitation 77 2 (2008) 170-179
3. von Lilienfeld-Toal M., Midgley K., Lieberbach S., Barnard L., Glasmacher A., Gilleece M., et al. Observation-based early warning scores to detect impending critical illness predict in-hospital and overall survival in patients undergoing allogeneic stem cell transplantation. Biol Blood Marrow Transplant 13 5 (2007) 568-576
4. Guidelines for intensive care unit admission, discharge, and triage. Task Force of the American College of Critical Care Medicine, Society of Critical Care Medicine. Crit Care Med 1999;27(3):633-8.
5. Carlon G.C. Just say no. Crit Care Med 17 1 (1989) 106-107
6. Schuster D.P. Everything that should be done-not everything that can be done. Am Rev Respir Dis 145 3 (1992) 508-509
7. Ethical and moral guidelines for the initiation, continuation, and withdrawal of intensive care. American College of Chest Physicians/Society of Critical Care Medicine Consensus Panel. Chest 1990;97(4):949-58.
8. Marco C.A., Larkin G.L., Moskop J.C., and Derse A.R. Determination of "futility" in emergency medicine. Ann Emerg Med 35 6 (2000) 604-612
9. The British Medical Association, The Resuscitation Council (UK), The Royal College of Nursing. Decisions relating to cardiopulmonary resuscitation. ; 2007 [accessed 12.12.08].
10. Carlet J, Thijs LG, Antonelli M, Cassell J, Cox P, Hill N, et al. Challenges in end-of-life care in the ICU. Statement of the 5th International Consensus Conference in Critical Care: Brussels, Belgium, April 2003. Intensive Care Med 2004;30(5):770-84.
11. Predicting outcome in ICU patients. 2nd European Consensus Conference in Intensive Care Medicine. Intensive Care Med 1994;20(5):390-7.
12. Consensus statement on the triage of critically ill patients. Society of Critical Care Medicine Ethics Committee. JAMA 1994;271(15):1200-3.
13. Hauser M.J., Tabak J., and Baier H. Survival of patients with cancer in a medical critical care unit. Arch Intern Med 142 3 (1982) 527-529
14. Carlon G.C. Admitting cancer patients to the intensive care unit. Crit Care Clin 4 1 (1988) 183-191
15. Raoof N.D., and Groeger J.S. You never know-one of your patients with cancer might surprise you. Crit Care Med 35 3 (2007) 965-966
16. Chevrolet J.C., and Jolliet P. An ethical look at intensive care for patients with malignancies. Eur J Cancer 27 2 (1991) 210-212
17. Sculier J.P., and Markiewicz E. Intensive care in anticancer centres: an international inquiry. Support Care Cancer 3 2 (1995) 130-134
18. Merz T.M., Schar P., Buhlmann M., Takala J., and Rothen H.U. Resource use and outcome in critically ill patients with hematological malignancy: a retrospective cohort study. Crit Care 12 3 (2008) R75
19. Schapira D.V., Studnicki J., Bradham D.D., Wolff P., and Jarrett A. Intensive care, survival, and expense of treating critically ill cancer patients. JAMA 269 6 (1993) 783-786
20. Brenner H. Long-term survival rates of cancer patients achieved by the end of the 20th century: a period analysis. Lancet 360 9340 (2002) 1131-1135
21. Azoulay E., Alberti C., Bornstain C., Leleu G., Moreau D., Recher C., et al. Improved survival in cancer patients requiring mechanical ventilatory support: impact of noninvasive mechanical ventilatory support. Crit Care Med 29 3 (2001) 519-525
22. Berghmans T., Paesmans M., and Sculier J.P. Is a specific oncological scoring system better at predicting the prognosis of cancer patients admitted for an acute medical complication in an intensive care unit than general gravity scores?. Support Care Cancer 12 4 (2004) 234-239
23. Blot F., Guiguet M., Nitenberg G., Leclercq B., Gachot B., and Escudier B. Prognostic factors for neutropenic patients in an intensive care unit: respective roles of underlying malignancies and acute organ failures. Eur J Cancer 33 7 (1997) 1031-1037
24. Brunet F., Lanore J.J., Dhainaut J.F., Dreyfus F., Vaxelaire J.F., Nouira S., et al. Is intensive care justified for patients with haematological malignancies?. Intensive Care Med 16 5 (1990) 291-297
25. Kress J.P., Christenson J., Pohlman A.S., Linkin D.R., and Hall J.B. Outcomes of critically ill cancer patients in a university hospital setting. Am J Respir Crit Care Med 160 6 (1999) 1957-1961
26. Larche J., Azoulay E., Fieux F., Mesnard L., Moreau D., Thiery G., et al. Improved survival of critically ill cancer patients with septic shock. Intensive Care Med 29 10 (2003) 1688-1695
27. Lecuyer L., Chevret S., Thiery G., Darmon M., Schlemmer B., and Azoulay E. The ICU trial: a new admission policy for cancer patients requiring mechanical ventilation. Crit Care Med 35 3 (2007) 808-814
28. Maschmeyer G., Bertschat F.L., Moesta K.T., Hausler E., Held T.K., Nolte M., et al. Outcome analysis of 189 consecutive cancer patients referred to the intensive care unit as emergencies during a 2-year period. Eur J Cancer 39 6 (2003) 783-792
29. Sculier J.P., Paesmans M., Markiewicz E., and Berghmans T. Scoring systems in cancer patients admitted for an acute complication in a medical intensive care unit. Crit Care Med 28 8 (2000) 2786-2792
30. Soares M., Salluh J.I., Spector N., and Rocco J.R. Characteristics and outcomes of cancer patients requiring mechanical ventilatory support for >24 h. Crit Care Med 33 3 (2005) 520-526
31. Soubani A.O., Kseibi E., Bander J.J., Klein J.L., Khanchandani G., Ahmed H.P., et al. Outcome and prognostic factors of hematopoietic stem cell transplantation recipients admitted to a medical ICU. Chest 126 5 (2004) 1604-1611
32. Staudinger T., Stoiser B., Mullner M., Locker G.J., Laczika K., Knapp S., et al. Outcome and prognostic factors in critically ill cancer patients admitted to the intensive care unit. Crit Care Med 28 5 (2000) 1322-1328
33. Vallot F., Paesmans M., Berghmans T., and Sculier J.P. Leucopenia is an independent predictor in cancer patients requiring invasive mechanical ventilation: a prognostic factor analysis in a series of 168 patients. Support Care Cancer 11 4 (2003) 236-241
34. Beck D.H., Smith G.B., Pappachan J.V., and Millar B. External validation of the SAPS II, APACHE II and APACHE III prognostic models in South England: a multicentre study. Intensive Care Med 29 2 (2003) 249-256
35. Rowan K.M., Kerr J.H., Major E., McPherson K., Short A., and Vessey M.P. Intensive Care Society's APACHE II study in Britain and Ireland-I: variations in case mix of adult admissions to general intensive care units and impact on outcome. BMJ 307 6910 (1993) 972-977
36. Wong D.T., Crofts S.L., Gomez M., McGuire G.P., and Byrick R.J. Evaluation of predictive ability of APACHE II system and hospital outcome in Canadian intensive care unit patients. Crit Care Med 23 7 (1995) 1177-1183
37. Alberti C., Brun-Buisson C., Burchardi H., Martin C., Goodman S., Artigas A., et al. Epidemiology of sepsis and infection in ICU patients from an international multicentre cohort study. Intensive Care Med 28 2 (2002) 108-121
38. Degoricija V., Sharma M., Legac A., Gradiser M., Sefer S., and Vucicevic Z. Survival analysis of 314 episodes of sepsis in medical intensive care unit in university hospital: impact of intensive care unit performance and antimicrobial therapy. Croat Med J 47 3 (2006) 385-397
39. Malacarne P., Langer M., Nascimben E., Moro M.L., Giudici D., Lampati L., et al. Building a continuous multicenter infection surveillance system in the intensive care unit: findings from the initial data set of 9493 patients from 71 Italian intensive care units. Crit Care Med 36 4 (2008) 1105-1113
40. Gopal I., Bhonagiri S., Ronco C., and Bellomo R. Out of hospital outcome and quality of life in survivors of combined acute multiple organ and renal failure treated with continuous venovenous hemofiltration/hemodiafiltration. Intensive Care Med 23 7 (1997) 766-772
41. Nolan J.P., Laver S.R., Welch C.A., Harrison D.A., Gupta V., and Rowan K. Outcome following admission to UK intensive care units after cardiac arrest: a secondary analysis of the ICNARC Case Mix Programme Database. Anaesthesia 62 12 (2007) 1207-1216
42. Crawford S.W., and Petersen F.B. Long-term survival from respiratory failure after marrow transplantation for malignancy. Am Rev Respir Dis 145 3 (1992) 510-514
43. DeNardo S.J., Oye R.K., and Bellamy P.E. Efficacy of intensive care for bone marrow transplant patients with respiratory failure. Crit Care Med 17 1 (1989) 4-6
44. Estopa R., Torres M.A., Kastanos N., Rives A., gusti-Vidal A., and Rozman C. Acute respiratory failure in severe hematologic disorders. Crit Care Med 12 1 (1984) 26-28
45. Ewer M.S., Ali M.K., Atta M.S., Morice R.C., and Balakrishnan P.V. Outcome of lung cancer patients requiring mechanical ventilation for pulmonary failure. JAMA 256 24 (1986) 3364-3366
46. Lloyd-Thomas A.R., Wright I., Lister T.A., and Hinds C.J. Prognosis of patients receiving intensive care for lifethreatening medical complications of haematological malignancy. Br Med J (Clin Res Ed) 296 6628 (1988) 1025-1029
47. Schuster D.P., and Marion J.M. Precedents for meaningful recovery during treatment in a medical intensive care unit. Outcome in patients with hematologic malignancy. Am J Med 75 3 (1983) 402-408
48. Yau E., Rohatiner A.Z., Lister T.A., and Hinds C.J. Long term prognosis and quality of life following intensive care for life-threatening complications of haematological malignancy. Br J Cancer 64 5 (1991) 938-942
49. Faber-Langendoen K., Caplan A.L., and McGlave P.B. Survival of adult bone marrow transplant patients receiving mechanical ventilation: a case for restricted use. Bone Marrow Transplant 12 5 (1993) 501-507
50. Azoulay E., Recher C., Alberti C., Soufir L., Leleu G., Le Jr. G., et al. Changing use of intensive care for hematological patients: the example of multiple myeloma. Intensive Care Med 25 12 (1999) 1395-1401
51. Ferra C., Marcos P., Misis M., Morgades M., Bordeje M.L., Oriol A., et al. Outcome and prognostic factors in patients with hematologic malignancies admitted to the intensive care unit: a single-center experience. Int J Hematol 85 3 (2007) 195-202
52. Jackson S.R., Tweeddale M.G., Barnett M.J., Spinelli J.J., Sutherland H.J., Reece D.E., et al. Admission of bone marrow transplant recipients to the intensive care unit: outcome, survival and prognostic factors. Bone Marrow Transplant 21 7 (1998) 697-704
53. Moran J.L., Solomon P.J., and Williams P.J. Assessment of outcome over a 10-year period of patients admitted to a multidisciplinary adult intensive care unit with haematological and solid tumours. Anaesth Intensive Care 33 1 (2005) 26-35
54. Rubenfeld G.D., and Crawford S.W. Withdrawing life support from mechanically ventilated recipients of bone marrow transplants: a case for evidence-based guidelines. Ann Intern Med 125 8 (1996) 625-633
55. Azoulay E., Thiery G., Chevret S., Moreau D., Darmon M., Bergeron A., et al. The prognosis of acute respiratory failure in critically ill cancer patients. Medicine (Baltimore) 83 6 (2004) 360-370
56. Bruennler T., Mandraka F., Zierhut S., Siebig S., Wrede C., Klebl F., et al. Outcome of hemato-oncologic patients with and without stem cell transplantation in a medical ICU. Eur J Med Res 12 8 (2007) 323-330
57. Benoit D.D., Vandewoude K.H., Decruyenaere J.M., Hoste E.A., and Colardyn F.A. Outcome and early prognostic indicators in patients with a hematologic malignancy admitted to the intensive care unit for a life-threatening complication. Crit Care Med 31 1 (2003) 104-112
58. Benoit D.D., Depuydt P.O., Vandewoude K.H., Offner F.C., Boterberg T., De Cock C.A., et al. Outcome in severely ill patients with hematological malignancies who received intravenous chemotherapy in the intensive care unit. Intensive Care Med 32 1 (2006) 93-99
59. Lamia B., Hellot M.F., Girault C., Tamion F., Dachraoui F., Lenain P., et al. Changes in severity and organ failure scores as prognostic factors in onco-hematological malignancy patients admitted to the ICU. Intensive Care Med 32 10 (2006) 1560-1568
60. Massion P.B., Dive A.M., Doyen C., Bulpa P., Jamart J., Bosly A., et al. Prognosis of hematologic malignancies does not predict intensive care unit mortality. Crit Care Med 30 10 (2002) 2260-2270
61. Park H.Y., Suh G.Y., Jeon K., Koh W.J., Chung M.P., Kim H., et al. Outcome and prognostic factors of patients with acute leukemia admitted to the intensive care unit for septic shock. Leuk Lymphoma 49 10 (2008) 1929-1934
62. Thakkar S.G., Fu A.Z., Sweetenham J.W., Mciver Z.A., Mohan S.R., Ramsingh G., et al. Survival and predictors of outcome in patients with acute leukemia admitted to the intensive care unit. Cancer 112 10 (2008) 2233-2240
63. Vandijck D.M., Benoit D.D., Depuydt P.O., Offner F.C., Blot S.I., Van Tilborgh A.K., et al. Impact of recent intravenous chemotherapy on outcome in severe sepsis and septic shock patients with hematological malignancies. Intensive Care Med 34 5 (2008) 847-855
64. Afessa B., Tefferi A., Dunn W.F., Litzow M.R., and Peters S.G. Intensive care unit support and Acute Physiology and Chronic Health Evaluation III performance in hematopoietic stem cell transplant recipients. Crit Care Med 31 6 (2003) 1715-1721
65. Khassawneh B.Y., White Jr. P., Anaissie E.J., Barlogie B., and Hiller F.C. Outcome from mechanical ventilation after autologous peripheral blood stem cell transplantation. Chest 121 1 (2002) 185-188
66. Pene F., Aubron C., Azoulay E., Blot F., Thiery G., Raynard B., et al. Outcome of critically ill allogeneic hematopoietic stem-cell transplantation recipients: a reappraisal of indications for organ failure supports. J Clin Oncol 24 4 (2006) 643-649
67. Price K.J., Thall P.F., Kish S.K., Shannon V.R., and Andersson B.S. Prognostic indicators for blood and marrow transplant patients admitted to an intensive care unit. Am J Respir Crit Care Med 158 3 (1998) 876-884
68. Ewig S., Torres A., Riquelme R., El-Ebiary M., Rovira M., Carreras E., et al. Pulmonary complications in patients with haematological malignancies treated at a respiratory ICU. Eur Respir J 12 1 (1998) 116-122
69. Gruson D., Hilbert G., Portel L., Boiron J.M., Bebear C.M., Vargas F., et al. Severe respiratory failure requiring ICU admission in bone marrow transplant recipients. Eur Respir J 13 4 (1999) 883-887
70. Huaringa A.J., Leyva F.J., Giralt S.A., Blanco J., Signes-Costa J., Velarde H., et al. Outcome of bone marrow transplantation patients requiring mechanical ventilation. Crit Care Med 28 4 (2000) 1014-1017
71. Kew A.K., Couban S., Patrick W., Thompson K., and White D. Outcome of hematopoietic stem cell transplant recipients admitted to the intensive care unit. Biol Blood Marrow Transplant 12 3 (2006) 301-305
72. Kroschinsky F., Weise M., Illmer T., Haenel M., Bornhaeuser M., Hoeffken G., et al. Outcome and prognostic features of intensive care unit treatment in patients with hematological malignancies. Intensive Care Med 28 9 (2002) 1294-1300
73. Paz H.L., Crilley P., Weinar M., and Brodsky I. Outcome of patients requiring medical ICU admission following bone marrow transplantation. Chest 104 2 (1993) 527-531
74. Rabbat A., Chaoui D., Montani D., Legrand O., Lefebvre A., Rio B., et al. Prognosis of patients with acute myeloid leukaemia admitted to intensive care. Br J Haematol 129 3 (2005) 350-357
75. Thiery G., Azoulay E., Darmon M., Ciroldi M., De M.S., Levy V., et al. Outcome of cancer patients considered for intensive care unit admission: a hospital-wide prospective study. J Clin Oncol 23 19 (2005) 4406-4413
76. Trinkaus M.A., Lapinsky S.E., Crump M., Keating A., Reece D.E., Chen C., et al. Predictors of mortality in patients undergoing autologous hematopoietic cell transplantation admitted to the intensive care unit. Bone Marrow Transplant 43 5 (2009) 411-415
77. Epner D.E., White P., Krasnoff M., Khanduja S., Kimball K.T., and Knaus W.A. Outcome of mechanical ventilation for adults with hematologic malignancy. J Investig Med 44 5 (1996) 254-260
78. Schellongowski P., Benesch M., Lang T., Traunmuller F., Zauner C., Laczika K., et al. Comparison of three severity scores for critically ill cancer patients. Intensive Care Med 30 3 (2004) 430-436
79. Torrecilla C., Cortes J.L., Chamorro C., Rubio J.J., Galdos P., and Dominguez de Villota E. Prognostic assessment of the acute complications of bone marrow transplantation requiring intensive therapy. Intensive Care Med 14 4 (1988) 393-398
80. Soares M., Fontes F., Dantas J., Gadelha D., Cariello P., Nardes F., et al. Performance of six severity-of-illness scores in cancer patients requiring admission to the intensive care unit: a prospective observational study. Crit Care 8 4 (2004) R194-R203
81. Benoit D.D., Depuydt P.O., Peleman R.A., Offner F.C., Vandewoude K.H., Vogelaers D.P., et al. Documented and clinically suspected bacterial infection precipitating intensive care unit admission in patients with hematological malignancies: impact on outcome. Intensive Care Med 31 7 (2005) 934-942
82. Groeger J.S., White Jr. P., Nierman D.M., Glassman J., Shi W., Horak D., et al. Outcome for cancer patients requiring mechanical ventilation. J Clin Oncol 17 3 (1999) 991-997
83. Azoulay E., Moreau D., Alberti C., Leleu G., Adrie C., Barboteu M., et al. Predictors of short-term mortality in critically ill patients with solid malignancies. Intensive Care Med 26 12 (2000) 1817-1823
84. Groeger J.S., Lemeshow S., Price K., Nierman D.M., White Jr. P., Klar J., et al. Multicenter outcome study of cancer patients admitted to the intensive care unit: a probability of mortality model. J Clin Oncol 16 2 (1998) 761-770
85. Soares M., Salluh J.I., Ferreira C.G., Luiz R.R., Spector N., and Rocco J.R. Impact of two different comorbidity measures on the 6-month mortality of critically ill cancer patients. Intensive Care Med 31 3 (2005) 408-415
86. Soares M., Salluh J.I., Torres V.B., Leal J.V., and Spector N. Short- and long-term outcomes of critically ill patients with cancer and prolonged ICU length of stay. Chest 134 3 (2008) 520-526
87. Norgaard M., Larsson H., Pedersen G., Schonheyder H.C., Rothman K.J., and Sorensen H.T. Short-term mortality of bacteraemia in elderly patients with haematological malignancies. Br J Haematol 132 1 (2006) 25-31
88. Yang T.M., Wang P.N., Kao K.C., Huang C.C., Tsai Y.H., and Hsieh M.J. Outcome of hematopoietic stem cell recipients who were mechanically ventilated and admitted to intensive care units. J Formos Med Assoc 106 4 (2007) 295-301
89. Ip S.P., Leung Y.F., Ip C.Y., and Mak W.P. Outcomes of critically ill elderly patients: is high-dependency care for geriatric patients worthwhile?. Crit Care Med 27 11 (1999) 2351-2357
90. Kaarlola A., Tallgren M., and Pettila V. Long-term survival, quality of life, and quality-adjusted life-years among critically ill elderly patients. Crit Care Med 34 8 (2006) 2120-2126
91. Peters S.G., Meadows III J.A., and Gracey D.R. Outcome of respiratory failure in hematologic malignancy. Chest 94 1 (1988) 99-102
92. Johnson M.H., Gordon P.W., and Fitzgerald F.T. Stratification of prognosis in granulocytopenic patients with hematologic malignancies using the APACHE-II severity of illness score. Crit Care Med 14 8 (1986) 693-697
93. Afessa B., Tefferi A., Hoagland H.C., Letendre L., and Peters S.G. Outcome of recipients of bone marrow transplants who require intensive-care unit support. Mayo Clin Proc 67 2 (1992) 117-122
94. Scott P.H., Morgan T.J., Durrant S., and Boots R.J. Survival following mechanical ventilation of recipients of bone marrow transplants and peripheral blood stem cell transplants. Anaesth Intensive Care 30 3 (2002) 289-294
95. Shorr A.F., Moores L.K., Edenfield W.J., Christie R.J., and Fitzpatrick T.M. Mechanical ventilation in hematopoietic stem cell transplantation: can we effectively predict outcomes?. Chest 116 4 (1999) 1012-1018
96. Naeem N., Reed M.D., Creger R.J., Youngner S.J., and Lazarus H.M. Transfer of the hematopoietic stem cell transplant patient to the intensive care unit: does it really matter?. Bone Marrow Transplant 37 2 (2006) 119-133
97. Ho V.T., Weller E., Lee S.J., Alyea E.P., Antin J.H., and Soiffer R.J. Prognostic factors for early severe pulmonary complications after hematopoietic stem cell transplantation. Biol Blood Marrow Transplant 7 4 (2001) 223-229
98. Benoit D.D., Hoste E.A., Depuydt P.O., Offner F.C., Lameire N.H., Vandewoude K.H., et al. Outcome in critically ill medical patients treated with renal replacement therapy for acute renal failure: comparison between patients with and those without haematological malignancies. Nephrol Dial Transplant 20 3 (2005) 552-558
99. Ferra C., Marcos P., Morgades M., Misis M., Bordeje M.L., and Ribera J.M. [Similar prognosis for transplanted and non-transplanted patients with hematological malignancy admitted to the intensive care unit]. Med Clin (Barc) 130 15 (2008) 573-575
100. Knaus W.A., Draper E.A., Wagner D.P., and Zimmerman J.E. APACHE II: a severity of disease classification system. Crit Care Med 13 10 (1985) 818-829
101. Le Jr. G., Lemeshow S., and Saulnier F. A new Simplified Acute Physiology Score (SAPS II) based on a European/North American multicenter study. JAMA 270 24 (1993) 2957-2963
102. Ohno-Machado L., Resnic F.S., and Matheny M.E. Prognosis in critical care. Annu Rev Biomed Eng 8 (2006) 567-599
103. den B.S., de Keizer N.F., and de J.E. Performance of prognostic models in critically ill cancer patients - a review. Crit Care 9 4 (2005) R458-R463
104. Bach P.B., Schrag D., Nierman D.M., Horak D., White Jr. P., Young J.W., et al. Identification of poor prognostic features among patients requiring mechanical ventilation after hematopoietic stem cell transplantation. Blood 98 12 (2001) 3234-3240
105. Le Jr. G., Klar J., Lemeshow S., Saulnier F., Alberti C., Artigas A., et al. The logistic organ dysfunction system. A new way to assess organ dysfunction in the intensive care unit. ICU Scoring Group. JAMA 276 10 (1996) 802-810
106. Minne L., bu-Hanna A., and de J.E. Evaluation of SOFA-based models for predicting mortality in the ICU: a systematic review. Crit Care 12 6 (2008) R161
107. Vincent J.L., Ferreira F., and Moreno R. Scoring systems for assessing organ dysfunction and survival. Crit Care Clin 16 2 (2000) 353-366
108. Guiguet M., Blot F., Escudier B., Antoun S., Leclercq B., and Nitenberg G. Severity-of-illness scores for neutropenic cancer patients in an intensive care unit: which is the best predictor? Do multiple assessment times improve the predictive value?. Crit Care Med 26 3 (1998) 488-493
109. Ackroyd R., Russon L., and Newell R. Views of oncology patients, their relatives and oncologists on cardiopulmonary resuscitation (CPR): questionnaire-based study. Palliat Med 21 2 (2007) 139-144
110. Heyland D.K., Frank C., Groll D., Pichora D., Dodek P., Rocker G., et al. Understanding cardiopulmonary resuscitation decision making: perspectives of seriously ill hospitalized patients and family members. Chest 130 2 (2006) 419-428
111. Rose J.H., O'Toole E.E., Dawson N.V., Lawrence R., Gurley D., Thomas C., et al. Perspectives, preferences, care practices, and outcomes among older and middle-aged patients with late-stage cancer. J Clin Oncol 22 24 (2004) 4907-4917
112. Sears S.R., Woodward J.T., and Twillman R.K. What do I have to lose? Effects of a psycho-educational intervention on cancer patient preference for resuscitation. J Behav Med 30 6 (2007) 533-544
113. Diem S.J., Lantos J.D., and Tulsky J.A. Cardiopulmonary resuscitation on television. Miracles and misinformation. N Engl J Med 334 24 (1996) 1578-1582
114. Reisfield G.M., Wallace S.K., Munsell M.F., Webb F.J., Alvarez E.R., and Wilson G.R. Survival in cancer patients undergoing in-hospital cardiopulmonary resuscitation: a meta-analysis. Resuscitation 71 2 (2006) 152-160
115. Murphy D.J., Burrows D., Santilli S., Kemp A.W., Tenner S., Kreling B., et al. The influence of the probability of survival on patients' preferences regarding cardiopulmonary resuscitation. N Engl J Med 330 8 (1994) 545-549
116. Peberdy M.A., Kaye W., Ornato J.P., Larkin G.L., Nadkarni V., Mancini M.E., et al. Cardiopulmonary resuscitation of adults in the hospital: a report of 14720 cardiac arrests from the National Registry of Cardiopulmonary Resuscitation. Resuscitation 58 3 (2003) 297-308
117. FitzGerald J.D., Wenger N.S., Califf R.M., Phillips R.S., Desbiens N.A., Liu H., et al. Functional status among survivors of in-hospital cardiopulmonary resuscitation. SUPPORT Investigators Study to Understand Progress and Preferences for Outcomes and Risks of Treatment. Arch Intern Med 157 1 (1997) 72-76
118. Gwinnutt C.L., Columb M., and Harris R. Outcome after cardiac arrest in adults in UK hospitals: effect of the 1997 guidelines. Resuscitation 47 2 (2000) 125-135
119. Tunstall-Pedoe H., Bailey L., Chamberlain D.A., Marsden A.K., Ward M.E., and Zideman D.A. Survey of 3765 cardiopulmonary resuscitations in British hospitals (the BRESUS Study): methods and overall results. BMJ 304 6838 (1992) 1347-1351
120. Brindley P.G., Markland D.M., Mayers I., and Kutsogiannis D.J. Predictors of survival following in-hospital adult cardiopulmonary resuscitation. CMAJ 167 4 (2002) 343-348
121. Ebell M.H. Prearrest predictors of survival following in-hospital cardiopulmonary resuscitation: a meta-analysis. J Fam Pract 34 5 (1992) 551-558
122. Landry F.J., Parker J.M., and Phillips Y.Y. Outcome of cardiopulmonary resuscitation in the intensive care setting. Arch Intern Med 152 11 (1992) 2305-2308
123. Schultz S.C., Cullinane D.C., Pasquale M.D., Magnant C., and Evans S.R. Predicting in-hospital mortality during cardiopulmonary resuscitation. Resuscitation 33 1 (1996) 13-17
124. Ewer M.S., Kish S.K., Martin C.G., Price K.J., and Feeley T.W. Characteristics of cardiac arrest in cancer patients as a predictor of survival after cardiopulmonary resuscitation. Cancer 92 7 (2001) 1905-1912
125. Wallace S.K., Ewer M.S., Price K.J., and Feeley T.W. Outcome and cost implications of cardiopulmonary resuscitation in the medical intensive care unit of a comprehensive cancer center. Support Care Cancer 10 5 (2002) 425-429
126. O'Keeffe S., and Ebell M.H. Prediction of failure to survive following in-hospital cardiopulmonary resuscitation: comparison of two predictive instruments. Resuscitation 28 1 (1994) 21-25
127. Khalafi K., Ravakhah K., and West B.C. Avoiding the futility of resuscitation. Resuscitation 50 2 (2001) 161-166
128. Marik P.E., and Craft M. An outcomes analysis of in-hospital cardiopulmonary resuscitation: the futility rationale for do not resuscitate orders. J Crit Care 12 3 (1997) 142-146
129. Rosenberg M., Wang C., Hoffman-Wilde S., Hickam D., and Hickham D.c.t.H. Results of cardiopulmonary resuscitation. Failure to predict survival in two community hospitals. Arch Intern Med 153 11 (1993) 1370-1375
130. Sandroni C., Nolan J., Cavallaro F., and Antonelli M. In-hospital cardiac arrest: incidence, prognosis and possible measures to improve survival. Intensive Care Med 33 2 (2007) 237-245
131. Bowker L., and Stewart K. Predicting unsuccessful cardiopulmonary resuscitation (CPR): a comparison of three morbidity scores. Resuscitation 40 2 (1999) 89-95
132. Vitelli C.E., Cooper K., Rogatko A., and Brennan M.F. Cardiopulmonary resuscitation and the patient with cancer. J Clin Oncol 9 1 (1991) 111-115
133. Pene F., and Soares M. Can we still refuse ICU admission of patients with hematological malignancies?. Intensive Care Med 34 5 (2008) 790-792