Molecular cloning of two isoforms of 11β-hydroxylase and their expressions in the Nile tilapia, Oreochromis niloticus

General and Comparative Endocrinology

Volumn 165, Issue 1, 2010, Pages 34-41

  Zhang, Wei Li ^a   Zhou, Lin Yan ^b   Senthilkumaran, Balasubramanian ^b,c   Huang, Bao Feng ^a   Sudhakumari, Cheni Chery ^b,c   Kobayashi, Tohru ^b,d   Nagahama, Yoshitaka ^b   Wang, De Shou ^a,b  

^a BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^b NATIONAL INSTITUTE FOR BASIC BIOLOGY   (Japan)

^c UNIVERSITY OF HYDERABAD   (India)

^d EHIME UNIVERSITY   (Japan)

Author keywords

Alternative splicing; Nile tilapia; P450(11 ); Sex steroids; Testis

Indexed keywords

AMINO ACID; COMPLEMENTARY DNA; ESTRADIOL; FADROZOLE; STEROID 11BETA MONOOXYGENASE; TAMOXIFEN;

ALTERNATIVE RNA SPLICING; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EXON; FEMALE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LEYDIG CELL; MALE; MOLECULAR CLONING; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; ORYZIAS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; SEX DIFFERENTIATION; SPECIES DIFFERENTIATION; SPERMATOGENESIS; SPERMATOGONIUM; TESTIS; TILAPIA;

EID: 71649089799     PISSN: 00166480     EISSN: 10956840     Source Type: Journal    
DOI: 10.1016/j.ygcen.2009.05.018     Document Type: Article

References (38)

1. Alam M.A., Komuro H., Bhandari R.K., Nakamura S., Soyano K., and Nakamura M. Immunohistochemical evidence identifying the site of androgen production in the ovary of the protogynous grouper Epinephelus merra. Cell Tissue Res. 320 (2005) 323-329
2. Anwar A., Coghlan J.P., and Jeyaseelan K. Structure of an ovine CYP11B1 gene. DNA Seq. 8 (1998) 357-374
3. Baron D., Houlgatte R., Fostier A., and Guiguen Y. Expression profiling of candidate genes during ovary-to-testis trans-differentiation in rainbow trout masculinized by androgens. Gen. Comp. Endocrinol. 156 (2008) 369-378
4. Bhandari R.K., Nakamura M., Kobayashi T., and Nagahama Y. Suppression of steroidogenic enzyme expression during androgen-induced sex reversal in Nile tilapia (Oreochromis niloticus). Gen. Comp. Endocrinol. 145 (2006) 20-24
5. Cardwell J.R., and Liley N.R. Hormonal control of sex and color change in the stoplight parrotfish, Sparisoma viride. Gen. Comp. Endocrinol. 81 (1991) 7-20
6. Gotoh O., Tagashira Y., Iizuka T., and Fujii-Kuriyama Y. Structural characteristics of cytochrome P-450. Possible location of the hemebinding cystein in determined amino-acid sequence. J. Biochem. 93 (1983) 807-817
7. Ijiri S., Kaneko H., Kobayashi T., Wang D.S., Sakai F., Paul-Prasanth B., Nakamura M., and Nagahama Y. Sexual dimorphic expression of genes in gonads during early differentiation of a teleost fish, the Nile tilapia Oreochromis niloticus. Biol. Reprod. 78 (2008) 333-341
8. Jiao B.W., Huang X.G., Chan C.B., Zhang L., Wang D.S., and Cheng C.H.K. The co-existence of two growth hormone receptors in teleost fish and their differential signal transduction, tissue distribution and hormonal regulation of expression in seabream. J. Mol. Endocrinol. 36 (2006) 23-40
9. Jiang J.Q., Kobayashi T., Ge W., Kobayashi H., Tanaka M., Okamoto M., Nonaka Y., and Nagahama Y. Fish testicular 11beta-hydroxylase: cDNA cloning and mRNA expression during spermatogenesis. FEBS Lett. 397 (1996) 250-252
10. Jiang J.Q., Young G., Kobayashi T., and Nagahama Y. Eel (Anguilla japonica) testis 11beta-hydroxylase gene is expressed in interrenal tissue and its product lacks aldosterone synthesizing activity. Mol. Cell. Endocrinol. 146 (1998) 207-211
11. Jiang J.Q., Wang D.S., Senthilkumaran B., Kobayashi T., Kobayashi H.K., Yamaguchi A., Ge W., Young G., and Nagahama Y. Isolation, characterization and expression of 11b-hydroxysteroid dehydrogenase type 2 cDNAs from the testes of Japanese eel (Anguilla japonica) and Nile tilapia (Orechromis niloticus). J. Mol. Endocrinol. 31 (2003) 305-315
12. Kobayashi T., Kobayashi H.K., and Nagahama Y. Differential expression of vasa homologue gene in the germ cells during oogenesis and spermatogenesis in a teleost fish, tilapia, Oreochromis niloticus. Mech. Dev. 99 (2000) 139-142
13. Kobayashi T., Kajiura-Kobayashi H., and Nagahama Y. Induction of XY sex reversal by estrogen involves altered gene expression in a teleost, tilapia. Cytogenet. Genome Res. 101 (2003) 289-294
14. Kobayashi T., Kajiura-Kobayashi H., Guan G., and Nagahama Y. Sexual dimorphic expression of DMRT1 and Sox9a during gonadal differentiation and hormone-induced sex reversal in the teleost fish Nile tilapia (Oreochromis niloticus). Dev. Dyn. 237 (2008) 297-306
15. Kobayashi Y., Sunobe T., Kobayashi T., Nagahama Y., and Nakamura M. Gonadal structure of the serial-sex changing gobiid fish Trimma okinawae. Dev. Growth Differ. 47 (2005) 7-13
16. Kusakabe M., Kobayashi T., Todo T., Mark L.P., Nagahama Y., and Young G. Molecular cloning and expression during spermatogenesis of a cDNA encoding testicular 11beta-hydroxylase (P45011beta) in rainbow trout (Oncorhynchus mykiss). Mol. Reprod. Dev. 62 (2002) 456-469
17. Kusakabe M., Nakamura I., and Young G. 11beta-hydroxysteroid dehydrogenase complementary deoxyribonucleic acid in rainbow trout: cloning, sites of expression, and seasonal changes in gonads. Endocrinology 144 (2003) 2534-2545
18. Liu S., Govoroun M., D'Cotta H., Ricordel M.J., Lareyre J.J., McMeel O.M., Smith T., Nagahama Y., and Guiguen Y. Expression of cytochrome P450(11beta) (11beta-hydroxylase) gene during gonadal sex differentiation and spermatogenesis in rainbow trout, Oncorhynchus mykiss. J. Steroid. Biochem. Mol. Biol. 75 (2000) 291-298
19. Mayer I., Borg B., and Schulz R. Seasonal changes in and effect of castration/androgen replacement on the plasma levels of five androgens in the male three-spined stickleback, Gasterosteus aculeatus. L. Gen. Comp. Endocrinol. 79 (1990) 23-30
20. Maugars G., and Schmitz M. Gene expression profiling during spermatogenesis in early maturing male Atlantic salmon parr testes. Gen. Comp. Endocrinol. 159 (2008) 178-187
21. Miura T., Yamauchi K., Takahashi H., and Nagahama Y. Hormonal induction of all stages of spermatogenesis in vitro in the male Japanese eel (Anguilla japonica). Proc. Natl. Acad. Sci. 88 (1991) 5774-5778
22. Morohashi K., Yoshioka H., Gotoh O., Okada Y., Yamamoto K., Miyata T., Sogawa K., Fujii-Kuriyama Y., and Omura T. Molecular cloning and nucleotide sequence of DNA of mitochondrial cytochrome P-450(11b) of bovine adrenal cortex. J. Biochem. 102 (1987) 559-568
23. Morohashi K.I., and Omura T. Ad4BP/SF-1, a transcription factor essential for the transcription of steroidogenic cytochrome P450 genes and for the establishment of the reproductive function. FASEB J. 10 (1996) 1569-1577
24. Nagahama Y. Endocrine regulation of gametogenesis in fish. Int. J. Dev. Biol. 38 (1994) 217-229
25. Nagahama Y. Gonadal steroid hormones: major regulators of gonadal sex differentiation and gametogenesis in fish. In: Norberg B., Kjesbu O.S., Taranger G.L., Andersson E., and Stefansson S.O. (Eds). Proceedings of the 6th International Symposium on Reproductive Physiology of Fish (2000), Institute of Marine Research and University of Bergen, Bergen, Norway 211-222
26. Nonaka Y., Takemori H., Halder S.K., Sun T., Ohta M., Hatano O., Takakusu A., and Okamoto M. Frog cytochrome P-450 (11b, aldo), a single enzyme involved in the final steps of glucocorticoid and mineralocorticoid biosynthesis. Eur. J. Biochem. 229 (1995) 249-256
27. Poulos T.L., Finzel B.C., and Howard A.J. High-resolution crystal structure of cytochrome P450cam. J. Mol. Biol. 195 (1987) 687-700
28. Rasheeda M., Sreenivasulu G., Swapna I., Raghuveer K., Wang D., Thangaraj K., Gupta A., and Senthilkumaran B. Thiourea-induced alteration in the expression patterns of some steroidogenic enzymes in the air-breathing catfish Clarias gariepinus. Fish Physiol. Biochem. 31 (2005) 275-279
29. Socorro S., Martins R.S., Deloffre L., Mylonas C.C., and Canario A.V. A cDNA for European sea bass (Dicentrachus labrax) 11beta-hydroxylase: gene expression during the thermosensitive period and gonadogenesis. Gen. Comp. Endocrinol. 150 (2007) 164-173
30. Sudhakumari C.C., Kobayashi T., Kajiura-Kobayashi H., Wang D.S., Yoshikuni M., Nagahama Y., and Senthilkumaran B. Ontogenic expression patterns of several nuclear receptors and cytochrome P450 aromatases in brain and gonads of the Nile tilapia Oreochromis niloticus suggests their involvement in sex differentiation. Fish Physiol. Biochem. 31 (2005) 129-135
31. Viñas J., and Piferrer F. Stage-specific gene expression during fish spermatogenesis as determined by laser-capture microdissection and quantitative-PCR in sea bass (Dicentrarchus labrax) Gonads. Biol. Reprod. 79 (2008) 738-747
32. Vizziano D., Randuineau G., Baron D., Cauty C., and Guiguen Y. Characterization of early molecular sex differentiation in rainbow trout, Oncorhynchus mykiss. Dev. Dyn. 236 (2007) 2198-2206
33. Wang G.M., Ge R.S., Latif S.A., Morris D.J., and Hardy M.P. Expression of 11beta-hydroxylase in rat Leydig cells. Endocrinology 143 (2002) 621-626
34. Wang D.S., Jiao B., Hu C., Huang X., Liu Z., and Cheng C.H. Discovery of a gonad-specific IGF subtype in teleost. Biochem. Biophys. Res. Commun. 367 (2008) 336-341
35. Wang D.S., Kobayashi T., Zhou L.Y., Paul-Prasanth B., Ijiri S., Sakai F., Okubo K., Morohashi K., and Nagahama Y. Foxl2 up-regulates aromatase gene transcription in a female-specific manner by binding to the promoter as well as interacting with Ad4 binding protein/steroidogenic factor 1. Mol. Endocrinol. 21 (2007) 712-725
36. Yokota H., Abe T., Nakai M., Murakami H., Eto C., and Yakabe Y. Effects of 4-tert-pentylphenol on the gene expression of P450 11beta-hydroxylase in the gonad of medaka (Oryzias latipes). Aquat. Toxicol. 71 (2005) 121-132
37. Yazawa T., Uesaka M., Inaoka Y., Mizutani T., Sekiguchi T., Kajitani T., Kitano T., Umezawa A., and Miyamoto K. Cyp11b1 is induced in the murine gonad by luteinizing hormone/human chorionic gonadotropin and involved in the production of 11-ketotestosterone, a major fish androgen: conservation and evolution of the androgen metabolic pathway. Endocrinology 149 (2008) 1786-1792
38. Zhou L.Y., Wang D.S., Kobayashi T., Yano A., Paul-Prasanth B., Suzuki A., Sakai F., and Nagahama Y. A novel type of P450c17 lacking the lyase activity is responsible for C21-steroid biosynthesis in the fish ovary and head kidney. Endocrinology 148 (2007) 4282-4291