Numerical study of BSA ultrafiltration in the limiting flux regime - Effect of variable physical properties

Desalination

Volumn 249, Issue 3, 2009, Pages 1139-1150

  Afonso, A ^a   Miranda, J M ^b   Campos, J B L M ^a  

^a UNIVERSITY OF PORTO   (Portugal)

^b UNIVERSIDADE LUSÓFONA DE HUMANIDADES E TECNOLOGIAS   (Portugal)

Author keywords

BSA; Computational fluid dynamics; Concentration dependent properties; Concentration polarization; Limiting flux; Ultrafiltration

Indexed keywords

ANALYTICAL SOLUTIONS; CONCENTRATION DEPENDENCE; CONCENTRATION FIELDS; CONCENTRATION POLARIZATION; CONCENTRATION-DEPENDENT; DIFFUSIVITIES; EXPERIMENTAL DATA; LIMITING FLUX; MASS TRANSPORT EQUATION; NUMERICAL CODE; NUMERICAL RESULTS; NUMERICAL STUDIES; OSMOTIC PRESSURE; STREAM FUNCTION-VORTICITY FORMULATION;

BODY FLUIDS; COMPUTATIONAL FLUID DYNAMICS; CONCENTRATION (PROCESS); FLUID DYNAMICS; NUMERICAL METHODS; POLARIZATION; ULTRAFILTRATION;

NAVIER STOKES EQUATIONS;

COMPUTATIONAL FLUID DYNAMICS; EXPERIMENTAL STUDY; NAVIER-STOKES EQUATIONS; NUMERICAL METHOD; PHYSICAL PROPERTY; ULTRAFILTRATION;

EID: 71649083721     PISSN: 00119164     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.desal.2009.05.012     Document Type: Article

References (32)

1. van Reis R., Gadam S., Frautschy L.N., Orlando S., Goodrich E.M., Saksena S., Kuriyel R., Simpson C.M., Pearl S., and Zydney A.L. High-performance tangential flow filtration using charged membranes. Biotechnology and Bioengineering 56 (1997) 71
2. Cheang B., and Zydney A.L. A two-stage ultrafiltration process for fractionation of whey protein isolate. Journal of Membrane Science 231 (2004) 159
3. Ghosh R. Novel cascade ultrafiltration configuration for continuous, high-resolution protein-protein fractionation: a simulation study. Journal of Membrane Science 226 (2003) 85
4. Vilker V.L., Colton C.K., and Smith K.A. The osmotic pressure of concentrated protein solutions: effect of concentration and pH in saline solutions of bovine serum albumin. Journal of Colloid and Interface Science 79 (1981) 548
5. Meechai N., Jamieson A.M., and Blackwell J. Translational diffusion coefficients of bovine serum albumin in aqueous solution at high ionic strength. Journal of Colloid and Interface Science 218 (1999) 167-175
6. Yu Y.-X., Tian A.-W., and Gao G.-H. Prediction of collective diffusion coefficient of bovine serum albumin in aqueous electrolyte solution with hard-core two-Yukawa potential. Physical Chemistry Chemical Physics 7 (2005) 2423-2428
7. Gill W.N., Wiley D.E., Fell C.J.D., and Fane A.G. Effect of viscosity on concentration polarization in ultrafiltration. AICHE Journal 34 (1988) 1563
8. Sirshendu D., and Bhattacharya P.K. Mass transfer coefficient with suction including property variations in applications of cross-flow ultrafiltration. Separation and Purification Technology 16 (1999) 61
9. Jonsson G. Boundary layer phenomena during ultrafiltration of dextran and whey protein solutions. Desalination 51 (1984) 61
10. Howell J., Field R., and Wu D. Ultrafiltration of high-viscosity solutions: theoretical developments and experimental findings. Chemical Engineering Science 51 (1996) 1405
11. García-Molin V., Esplugas S., Wintgens Th., and Melin Th. Ultrafiltration of aqueous solutions containing dextran. Desalination 188 (2006) 217
12. Bowen W.R., and Williams PaulM. Prediction of the rate of cross-flow ultra filtration of colloids with concentration-dependent diffusion coefficient and viscosity: theory and experiment. Chemical Engineering Science 56 (2001) 3083
13. Magueijo V., de Pinho M.N., and Geraldes V. Numerical and experimental study of mass transfer in lysozyme ultrafiltration. Desalination 145 (2002) 193-199
14. Gaigalas A.K., Reipa V., Hubbard J.B., Edwards J., and Douglas J. A non-perturbative relation between the mutual diffusion coefficient, suspension viscosity and osmotic compressibility: application to concentrated protein solutions. Chemical Engineering Science 50 (1995) 1107
15. Pritchard M., Howell J.A., and Field R.W. The ultrafiltration of viscous fluids. Journal of Membrane Science 102 (1995) 223
16. Noordman T.R., Ketelaar T.H., Donkers F., and Wesselingh J.A. Concentration and desalination of protein solutions by ultrafiltration. Chemical Engineering Science 57 (2002) 693
17. Clifton M.J., Abidine N., Aptel P., and Sanches V. Growth of the polarization layer in ultrafiltration with hollow-fibre membranes. Journal of Membrane Science 21 (1984) 233
18. Jonsson G., and Boesen C.E. Concentration polarization in a reverse osmosis test cell. Desalination 21 (1977) 1
19. Wijmans J.G., Nakao S., van den Berg J.W.A., Troelstra F.R., and Smolders C.A. Hydrodynamic resistance of concentration polarization boundary layers in ultrafiltration. Journal of Membrane Science 22 (1985) 117
20. Zaidi S.K., and Kumar A. Experimental studies in the dead-end ultrafiltration of dextran: analysis of concentration polarization. Separation and Purification Technology 36 (2004) 115
21. Michaels A.S. New separation technique for the CPI. Chemical Engineering Progress 64 (1968) 31
22. Shen J.J.S., and Probstein R.F. On the prediction of limiting flux in laminar ultrafiltration of macromolecular solutions. Industrial & Engineering Chemistry Fundamentals 16 (1977) 459
23. Trettin D.R., and Doshi M.P. Limiting flux in ultrafiltration of macromolecular solutions. Chemical Engineering Communications 4 (1980) 507
24. Probstein R.F., Shen J.J.S., and Leung W.F. Ultrafiltration of macromolecular solutions at high polarization in laminar channel flow. Desalination 24 (1978) 1
25. Leung W., and Probstein R.F. Low polarization in laminar ultrafiltration of macromolecular solutions. Industrial & Engineering Chemistry Fundamentals 18 (1979) 274
26. Bhattacharjee S., Kim A.S., and Elimelech M. Concentration polarization of interacting solute particles in cross-flow membrane filtration. Journal of Colloid and Interface Science 212 (1999) 81-99
27. Fernández-Sempere M.J., Ruiz-Beviá F., and Salcedo-Díaz R. Visualization of the UF polarized layer by holographic interferometry. Journal of Membrane Science 229 (2004) 187-197
28. MacRitchie F. Effects of temperature on dissolution and precipitation of proteins and polyarnino acids. Journal of Colloid and Interface Science 45 (1973) 235
29. Zydney A.L. Stagnant film model for concentration polarization in membrane systems. Journal of Membrane Science 130 (1997) 275-281
30. Miranda J.M., and Campos J.B.L.M. An improved scheme to study mass transfer over a separation membrane. Journal of Membrane Science 188 (2001) 49
31. Miranda J.M., and Campos J.B.L.M. Concentration polarisation in a membrane placed under an impinging jet confined by a conical wall-a numerical approach. Journal of Membrane Science 182 (2000) 257
32. Miranda J.M., and Campos J.B.L.M. Mass transfer in the vicinity of a separation membrane - the applicability of the stagnant film theory. Journal of Membrane Science 202 (2002) 137