Simultaneous expression of glutathione, thioredoxin-1, and their reductases in nerve transected hypoglossal motor neurons of rat

Brain Research

Volumn 1306, Issue , 2010, Pages 1-7

  Hama, Isuzu ^a   Nakagomi, Saya ^a   Konishi, Hiroyuki ^a   Kiyama, Hiroshi ^a  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Hypoglossal; Nerve injury; Neuronal protection; Rat; Redox system

Indexed keywords

GLUTATHIONE REDUCTASE; MESSENGER RNA; THIOREDOXIN 1; THIOREDOXIN 2;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; IN SITU HYBRIDIZATION; MALE; MOTONEURON; NERVE TRANSECTION; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UPREGULATION;

RATTUS;

EID: 71549173423     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2009.10.014     Document Type: Article

References (22)

1. Bai J., Nakamura H., Kwon Y.W., Hattori I., Yamaguchi Y., Kim Y.C., Kondo N., Oka S., Ueda S., Masutani H., and Yodoi J. Critical roles of thioredoxin in nerve growth factor-mediated signal transduction and neurite outgrowth in PC12 cells. J. Neurosci. 23 (2003) 503-509
2. Bossy-Wetzel E., Schwarzenbacher R., and Lipton S.A. Molecular pathways to neurodegeneration. Nat. Med. 10 Suppl (2004) S2-S9
3. Conrad M., Jakupoglu C., Moreno S.G., Lippl S., Banjac A., Schneider M., Beck H., Hatzopoulos A.K., Just U., Sinowatz F., Schmahl W., Chien K.R., Wurst W., Bornkamm G.W., and Brielmeier M. Essential role for mitochondrial thioredoxin reductase in hematopoiesis, heart development, and heart function. Mol. Cell. Biol. 24 (2004) 9414-9423
4. Fonnum F., and Lock E.A. The contributions of excitotoxicity, glutathione depletion and DNA repair in chemically induced injury to neurones: exemplified with toxic effects on cerebellar granule cells. J. Neurochem. 88 (2004) 513-531
5. Fukui H., and Moraes C.T. The mitochondrial impairment, oxidative stress and neurodegeneration connection: reality or just an attractive hypothesis?. Trends Neurosci. 31 (2008) 251-256
6. Gamo K., Kiryu-Seo S., Konishi H., Aoki S., Matsushima K., Wada K., and Kiyama H. G-protein-coupled receptor screen reveals a role for chemokine receptor CCR5 in suppressing microglial neurotoxicity. J. Neurosci. 28 (2008) 11980-11988
7. Hansen J.M., Watson W.H., and Jones D.P. Compartmentation of Nrf-2 redox control: regulation of cytoplasmic activation by glutathione and DNA binding by thioredoxin-1. Toxicol. Sci. 82 (2004) 308-317
8. Inomata Y., Nakamura H., Tanito M., Teratani A., Kawaji T., Kondo N., Yodoi J., and Tanihara H. Thioredoxin inhibits NMDA-induced neurotoxicity in the rat retina. J. Neurochem. 98 (2006) 372-385
9. Jakupoglu C., Przemeck G.K., Schneider M., Moreno S.G., Mayr N., Hatzopoulos A.K., de Angelis M.H., Wurst W., Bornkamm G.W., Brielmeier M., and Conrad M. Cytoplasmic thioredoxin reductase is essential for embryogenesis but dispensable for cardiac development. Mol. Cell. Biol. 25 (2005) 1980-1988
10. Jones D.P. Radical-free biology of oxidative stress. Am. J. Physiol. Cell. Physiol. 295 (2008) C849-C868
11. Kiryu-Seo S., Gamo K., Tachibana T., Tanaka K., and Kiyama H. Unique anti-apoptotic activity of EAAC1 in injured motor neurons. EMBO J. 25 (2006) 3411-3421
12. Kondo N., Nakamura H., Masutani H., and Yodoi J. Redox regulation of human thioredoxin network. Antioxid. Redox Signal. 8 (2006) 1881-1890
13. Maher P. Redox control of neural function: background, mechanisms, and significance. Antioxid. Redox Signal. 8 (2006) 1941-1970
14. Mansur K., Iwahashi Y., Kiryu-Seo S., Su Q., Namikawa K., Yodoi J., and Kiyama H. Up-regulation of thioredoxin expression in motor neurons after nerve injury. Brain Res. Mol. Brain Res. 62 (1998) 86-91
15. Masutani H., Ueda S., and Yodoi J. The thioredoxin system in retroviral infection and apoptosis. Cell Death Differ. 12 Suppl 1 (2005) 991-998
16. Mustacich D., and Powis G. Thioredoxin reductase. Biochem. J. 346 Pt 1 (2000) 1-8
17. Raivich G., and Makwana M. The making of successful axonal regeneration: genes, molecules and signal transduction pathways. Brain Res. Rev. 53 (2007) 287-311
18. Soerensen J., Jakupoglu C., Beck H., Forster H., Schmidt J., Schmahl W., Schweizer U., Conrad M., and Brielmeier M. The role of thioredoxin reductases in brain development. PLoS ONE 3 (2008) e1813
19. Takagi Y., Tokime T., Nozaki K., Gon Y., Kikuchi H., and Yodoi J. Redox control of neuronal damage during brain ischemia after middle cerebral artery occlusion in the rat: immunohistochemical and hybridization studies of thioredoxin. J. Cereb. Blood Flow Metab. 18 (1998) 206-214
20. Tanito M., Kwon Y.W., Kondo N., Bai J., Masutani H., Nakamura H., Fujii J., Ohira A., and Yodoi J. Cytoprotective effects of geranylgeranylacetone against retinal photooxidative damage. J. Neurosci. 25 (2005) 2396-2404
21. Vargas M.R., Pehar M., Cassina P., Beckman J.S., and Barbeito L. Increased glutathione biosynthesis by Nrf2 activation in astrocytes prevents p75NTR-dependent motor neuron apoptosis. J. Neurochem. 97 (2006) 687-696
22. Yoneda T., Inagaki S., Hayashi Y., Nomura T., and Takagi H. Differential regulation of manganese and copper/zinc superoxide dismutases by the facial nerve transection. Brain Res. 582 (1992) 342-345