Gene expression profiles of mouse spermatogenesis during recovery from irradiation

Reproductive Biology and Endocrinology

Volumn 7, Issue , 2009, Pages

  Shah, Fozia J ^a   Tanaka, Masami ^b,c   Nielsen, John E ^a   Iwamoto, Teruaki ^d   Kobayashi, Shinichi ^c   Skakkebæk, Niels E ^a   Leffers, Henrik ^a   Almstrup, Kristian ^a  

^a International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health   (Denmark)

^b ST MARIANNA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c ST MARIANNA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d International University of Health and Welfare   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR GATA 1; DAZL PROTEIN, MOUSE; GATA1 PROTEIN, MOUSE; NUCLEAR PROTEIN; RNA BINDING PROTEIN; TNP2 PROTEIN, MOUSE; VESICULAR TRANSPORT PROTEIN; VPS26 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; GAP JUNCTION; GENE EXPRESSION PROFILING; GERM CELL; IN SITU HYBRIDIZATION; IRRADIATION; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; RADIATION DOSE FRACTIONATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SERTOLI CELL; SPERMATOGENESIS; SPERMATOGONIUM; TESTIS; TESTIS WEIGHT; ANIMAL; ANIMAL DISEASE; ANTIBODY SPECIFICITY; BODY WEIGHT; C3H MOUSE; CONVALESCENCE; GENETICS; HISTOLOGY; METABOLISM; ORGAN SIZE; PHYSIOLOGY; RADIATION EXPOSURE; WHOLE BODY RADIATION;

MUS;

ANIMALS; BODY WEIGHT; GATA1 TRANSCRIPTION FACTOR; GENE EXPRESSION PROFILING; MALE; MICE; MICE, INBRED C3H; NUCLEAR PROTEINS; ORGAN SIZE; ORGAN SPECIFICITY; RECOVERY OF FUNCTION; RNA-BINDING PROTEINS; SPERMATOGENESIS; SPERMATOGONIA; TESTIS; VESICULAR TRANSPORT PROTEINS; WHOLE-BODY IRRADIATION;

EID: 71549115443     PISSN: None     EISSN: 14777827     Source Type: Journal    
DOI: 10.1186/1477-7827-7-130     Document Type: Article

References (40)

1. Efstathiou E, Logothetis C. Review of late complications of treatment and late relapse in testicular cancer. J Natl Compr Canc Netw 2006, 4(10):1059-1070.
2. Russell L, Ettlin R, Sinha Hikim A, Clegg E. Histological and histopathological evaluation of the testis. 1990, Clearwater, FL: Cache River Press, 1.
3. Meistrich M. Effects of chemotherapy and radiotherapy on spermatogenesis. Eur Urol 1993, 23(1):136-141. 8477773.
4. Shetty G, Meistrich M. Hormonal approaches to preservation and restoration of male fertility after cancer treatment. J Natl Cancer Inst Monogr 2005, (34):36-39. 10.1093/jncimonographs/lgi002, 15784820.
5. Fosså S, Magelssen H. Fertility and reproduction after chemotherapy of adult cancer patients: malignant lymphoma and testicular cancer. Ann Oncol 2004, 15(Suppl 4):iv259-265.
6. de Rooij D, Russell L. All you wanted to know about spermatogonia but were afraid to ask. J Androl 2000, 21(6):776-798.
7. Huckins C. The spermatogonial stem cell population in adult rats. I. Their morphology, proliferation and maturation. Anat Rec 1971, 169(3):533-557. 10.1002/ar.1091690306, 5550532.
8. Sharpe R. Regulation of spermatogenesis. The Physiology of Reproduction 1994, 1363-1434. New York: Raven Press, Inc, Knobil EaN JD, 2.
9. Oakberg E. A description of spermiogenesis in the mouse and its use in analysis of the cycle of the seminiferous epithelium and germ cell renewal. Am J Anat 1956, 99(3):391-413. 10.1002/aja.1000990303, 13402725.
10. Oakberg E. Gamma-ray sensitivity of spermatogonia of the mouse. J Exp Zool 1957, 134(2):343-356. 10.1002/jez.1401340208, 13428958.
11. Oakberg E. Initial depletion and subsequent recovery of spermatogonia of the mouse after 20 r of gamma rays and 100, 300, and 600 r of x-rays. Radiat Res 1959, 11:700-719. 10.2307/3570749, 14428127.
12. Meistrich M. Quantitative correlation between testicular stem cell survival, sperm production, and fertility in the mouse after treatment with different cytotoxic agents. J Androl 1982, 3:58-68.
13. Meistrich M, Wilson G, Mathur K, Fuller L, Rodriguez M, McLaughlin P, Romaguera J, Cabanillas F, Ha C, Lipshultz L, Hagemeister FB. Rapid recovery of spermatogenesis after mitoxantrone, vincristine, vinblastine, and prednisone chemotherapy for Hodgkin's disease. J Clin Oncol 1997, 15(12):3488-3495.
14. Meer Y, Huiskamp R, Davids J, Tweel I, de Rooij D. The sensitivity of quiescent and proliferating mouse spermatogonial stem cells to X irradiation. Radiat Res 1992, 130(3):289-295. 10.2307/3578373, 1594754.
15. Meer Y, Huiskamp R, Davids J, Tweel I, de Rooij D. The sensitivity to X rays of mouse spermatogonia that are committed to differentiate and of differentiating spermatogonia. Radiat Res 1992, 130(3):296-302. 10.2307/3578374, 1594755.
16. Dym M, Clermont Y. Role of spermatogonia in the repair of the seminiferous epithelium following x-irradiation of the rat testis. Am J Anat 1970, 128(3):265-282. 10.1002/aja.1001280302, 4193812.
17. Pinon-Lataillade G, Maas J. Continuous gamma-irradiation of rats: dose-rate effect on loss and recovery of spermatogenesis. Strahlentherapie 1985, 161(7):421-426.
18. Bustos-Obregón E, Rodriguez H. Testicular x-ray irradiation in adult mice as a model to study spermatogonial proliferation. Andrologia 1991, 23(6):447-450.
19. West A, Lähdetie J. X-irradiation--induced changes in the progression of type B spermatogonia and preleptotene spermatocytes. Mol Reprod Dev 2001, 58(1):78-87. 10.1002/1098-2795(200101)58:1<78::AID-MRD11>3.0.CO;2-J, 11144224.
20. Withers H, Hunter N, Barkley HJ, Reid B. Radiation survival and regeneration characteristics of spermatogenic stem cells of mouse testis. Radiat Res 1974, 57(1):88-103. 10.2307/3573759, 10874929.
21. Meistrich M. Critical components of testicular function and sensitivity to disruption. Biol Reprod 1986, 34(1):17-28. 10.1095/biolreprod34.1.17, 3955133.
22. van Beek M, Meistrich M, de Rooij D. Probability of self-renewing divisions of spermatogonial stem cells in colonies, formed after fission neutron irradiation. Cell Tissue Kinet 1990, 23(1):1-16.
23. Mian T, Suzuki N, Glenn H, Haynie T, Meistrich M. Radiation damage to mouse testis cells from [99 mTc] pertechnetate. J Nucl Med 1977, 18(11):1116-1122.
24. Meistrich M, Trostle P, Frapart M, Erickson R. Biosynthesis and localization of lactate dehydrogenase X in pachytene spermatocytes and spermatids of mouse testes. Dev Biol 1977, 60(2):428-441. 10.1016/0012-1606(77)90140-3, 924020.
25. Kreuser E, Kurrle E, Hetzel W, Heymer B, Porzsolt F, Hautmann R, Gaus W, Schlipf U, Pfeiffer E, Heimpel H. [Reversible germ cell toxicity following aggressive chemotherapy in patients with testicular tumors: results of a prospective study]. Klin Wochenschr 1989, 67(7):367-378. 10.1007/BF01711264, 2501552.
26. Kangasniemi M, Cheng C, Toppari J, Grima J, Stahler M, Bardin C, Parvinen M. Basal and FSH-stimulated steady state levels of SGP-2, alpha 2-macroglobulin, and testibumin in culture media of rat seminiferous tubules at defined stages of the epithelial cycle. J Androl 1992, 13(3):208-213.
27. Rowley M, Leach D, Warner G, Heller C. Effect of graded doses of ionizing radiation on the human testis. Radiat Res 1974, 59(3):665-678. 10.2307/3574084, 4428015.
28. Meistrich M, Wilson G, Brown B, da Cunha M, Lipshultz L. Impact of cyclophosphamide on long-term reduction in sperm count in men treated with combination chemotherapy for Ewing and soft tissue sarcomas. Cancer 1992, 70(11):2703-2712. 10.1002/1097-0142(19921201)70:11<2703::AID-CNCR2820701123>3.0.CO;2-X, 1423201.
29. Zhang Z, Shao S, Meistrich M. The radiation-induced block in spermatogonial differentiation is due to damage to the somatic environment, not the germ cells. J Cell Physiol 2007, 211(1):149-158. 10.1002/jcp.20910, 17167785.
30. Zhang Z, Shao S, Shetty G, Meistrich M. Donor Sertoli cells transplanted into irradiated rat testes stimulate partial recovery of endogenous spermatogenesis. Reproduction 2009, 137(3):497-508. 10.1530/REP-08-0120, 19036951.
31. Porter K, Shetty G, Shuttlesworth G, Weng C, Huhtaniemi I, Pakarinen P, Meistrich M. Estrogen Enhances Recovery from Radiation-Induced Spermatogonial Arrest in Rat Testes. J Androl 2009,
32. Jørgensen M, Bévort M, Kledal T, Hansen B, Dalgaard M, Leffers H. Differential display competitive polymerase chain reaction: an optimal tool for assaying gene expression. Electrophoresis 1999, 20(2):230-240.
33. Nielsen J, Hansen M, Jørgensen M, Tanaka M, Almstrup K, Skakkebaek N, Leffers H. Germ cell differentiation-dependent and stage-specific expression of LANCL1 in rodent testis. Eur J Histochem 2003, 47(3):215-222.
34. Almstrup K, Nielsen J, Hansen M, Tanaka M, Skakkebaek N, Leffers H. Analysis of cell-type-specific gene expression during mouse spermatogenesis. Biol Reprod 2004, 70(6):1751-1761. 10.1095/biolreprod.103.026575, 14960480.
35. Shih D, Kleene K. A study by in situ hybridization of the stage of appearance and disappearance of the transition protein 2 and the mitochondrial capsule seleno-protein mRNAs during spermatogenesis in the mouse. Mol Reprod Dev 1992, 33(2):222-227. 10.1002/mrd.1080330216, 1418993.
36. Hansen M, Nielsen J, Tanaka M, Almstrup K, Skakkebaek N, Leffers H. Identification and expression profiling of 10 novel spermatid expressed CYPT genes. Mol Reprod Dev 2006, 73(5):568-579. 10.1002/mrd.20463, 16477651.
37. Zhou W, Bolden-Tiller O, Shetty G, Shao S, Weng C, Pakarinen P, Liu Z, Stivers D, Meistrich M. Changes in Gene Expression in Somatic Cells of Rat Testes Resulting from Hormonal Modulation and Radiation-Induced Germ Cell Depletion. Biol Reprod 2009,
38. Huang W, Lin Y, Hsiao K, Eilber K, Salido E, Yen P. Restricted expression of the human DAZ protein in premeiotic germ cells. Hum Reprod 2008, 23(6):1280-1289. 10.1093/humrep/den099, 18385127.
39. Bellvé A, Millette C, Bhatnagar Y, O'Brien D. Dissociation of the mouse testis and characterization of isolated spermatogenic cells. J Histochem Cytochem 1977, 25(7):480-494.
40. Ivell R, Spiess A. Analysing Differential Gene Expression in the Testis. Testicular Tangrams 2002, (Workshop Supplement 9):99-120. Heidelberg: Springer, Rommerts F, Teerds K.