Autonomous beating and fluid pumping gel by cardiomycytes drug stimulation

TRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems

Volumn , Issue , 2009, Pages 769-772

  Imagawa, Kentaro ^a   Horiguchi, Hiroshi ^a   Ikeda, Kazumasa ^b   Akiyama, Yoshitake ^a   Hoshino, Takayuki ^a   Maruo, Shoji ^b   Morishima, Keisuke ^a  

^a TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY   (Japan)

^b YOKOHAMA NATIONAL UNIVERSITY   (Japan)

Author keywords

Bioactuator; Cardiomyocyte; Drug; Extracellular matrix

Indexed keywords

BIOACTUATORS; CARDIOMYOCYTES; CHECK VALVES; CONCENTRATION OF; EXTRACELLULAR MATRICES; FLUID PUMPING; MICRO PUMP; PUMPING APPLICATIONS; VOLUME CHANGE;

ACTUATORS; GELS; MICROSYSTEMS; PIEZOELECTRIC TRANSDUCERS; PUMPS;

SOLID-STATE SENSORS;

EID: 71449100034     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1109/SENSOR.2009.5285634     Document Type: Conference Paper

References (8)

1. I. W. Hunter, S. Lafontaine, "A Comparison of Muscle with Artificial Actuators", Solid-State Sensor and Actuator Workshop, 1992 5th Technical Digest, IEEE, pp. 178-185, 1992
2. Y. Akiyama, Y. Furukawa, K. Morishima, "Controllable bio-microactuator powered by muscle cells." Conf. Pro.c IEEE Eng. Med. Biol. Soc., Suppl: 6565-6568, 2006.
3. Y. Akiyama, K. Iwabuchi, Y. Furukawa, K. Morishima, "Culture of insect cells contracting spontaneously; research moving toward an environmentally robust hybrid robotic system." J. Biotechnol., vol.133, pp. 261-266, 2008.
4. S. Nishimura, S. Yasuda, M. Katoh, K.P. Yamada, H. Yamashita, Y. Saeki, K. Sunagawa, R. Nagai, T. Hisada, S. Sugiura, "Single cell mechanics of rat cardiomyocytes under isometric, unloaded, and physiologically loaded conditions." Am. J. Physiol. Heart Circulatory Physiol., 287, H196-H202, 2004.
5. K. Morishima, Y. Tanaka, M. Ebara, T. Shimizu, A. Kikuchi, M. Yamato, T. Okano, T. Kitamori, "Demonstration of a bio-microactuator powered by cultured cardiomyocytes coupled to hydrogel micropillars." Sensors and Actuators B-Chemical, vol.119, pp. 345-350, 2006.
6. T. Ishisaka, H. Sato, Y. Akiyama, Y. Furukawa, and K. Morishima, "Bio-actuated power generator using heart muscle cells on a PDMS membrane." Digest Tech. Papers Transducers'07 Conference, Lyon, France, pp. 903-906, June 10-14, 2007.
7. W.H. Zimmermann, K. Schneiderbanger, P. Schubert, M. Didié, F. Münzel, JF. Heubach, S. Kostin, W.L. Neuhuber, T. Eschenhagen, "Tissue Engineering of a Differentiated Cardiac Muscle Construct." Circ. Res, 90, pp.223-230, 2002.
8. Y. Itabashi, S. Miyoshi, S. Yuasa, J. Fujita, T. Shimizu, T. Okano, K. Fukuda, S. Ogawa, "Analysis of the electrophysiological properties and arrhythmias in directlycontacted skeletal and cardiac muscle cell sheets." Cardiovascular Research, 67, pp. 561-570, 2005.