First-line high-dose chemotherapy for 'poor risk' metastatic nonseminomatous testicular germ cell tumors

Onkologie

Volumn 21, Issue SUPPL. 2, 1998, Pages 23-25

  Bokemeyer, C ^a   Harstrick, A ^b   Beyer, J ^b   Metzner, B ^b   Ruther U ^b   Hartmann, J T ^b   Holstein, K ^b   Derigs, H G ^b   De Wit, R ^b   Casper, J ^b   Schoffski P ^b   Kuhrer I ^b   Illiger, H J ^b   Kempf, B ^b   Reichle, A ^b   Foller A ^b   Hossfeld, D K ^b   Fischer, J Th ^b   Berdel, W ^b   Gerhartz, H ^b   Kirchner, H ^b   Pfluger K ^b   Ostermann, H ^b   Kanz, L ^b   Schmoll, H J ^b   more..

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b NONE

Author keywords

Germ cell tumors; High dose chemotherapy; IGCCCG classification; Peripheral blood stem cells; Testicular cancer

Indexed keywords

CISPLATIN; ETOPOSIDE; GRANULOCYTE COLONY STIMULATING FACTOR; IFOSFAMIDE;

ADULT; AGED; CANCER COMBINATION CHEMOTHERAPY; CANCER RISK; CONFERENCE PAPER; CYTOSTASIS; DOSE RESPONSE; DRUG EFFECT; DRUG MEGADOSE; GERM CELL TUMOR; HIGH RISK POPULATION; HUMAN; MAJOR CLINICAL STUDY; MALE; SEMINOMA; STEM CELL TRANSPLANTATION; TESTIS CANCER;

EID: 7144263738     PISSN: 0378584X     EISSN: None     Source Type: Journal    
DOI: 10.1159/000054966     Document Type: Conference Paper

References (13)

1. Einhorn LH: Treatment of testicular cancer: A new and improved model. J Clin Oncol 1990;8:1777-1781.
2. Bosl GJ, Motzer RJ. Testicular germ cell cancer. N Engl J Med 1997;337:242-253.
3. Bosl GJ, Geller NL, Cirricone C, Vogelzang NJ, Kennedy BJ, Whitmore WF, Vugrin D, Scher H, Nisselbaum J, Golbey RB: Multivariate analysis of prognostic variables in patients with metastatic testicular cancer. Cancer Res 1983;43:3403-3407.
4. Birch R, Williams S, Cone A, Einhorn L, Roark P, Turner S, Greco FA: Prognostic factors for favourable outcome in disseminated germ cell tumors. J Clin Oncol 1986;4 400-407.
5. International Germ Cell Cancer Collaborative. International Germ Cell Consensus Classification: A Prognostic Factor-Based Staging System for Metastatic Germ Cell Cancers. J Clin Oncol 1997;15:594-603.
6. Motzer RJ, Mazumdar M, Subhash CG, Bajorin DF, Lyn P, Vlamis V, Bosl GJ: Phase II trial of high-dose carboplatin and etoposide with autologous bone marrow transplantation in first-line therapy for patients with poor-risk germ cell tumors. J Natl Cancer Inst 1993;85:1828-1835.
7. Chevreau C, Droz JP, Pico JC, Biron P, Kerbrat P, Cure H, Héron JF, Chavalli B, Fargeot P, Kramar A, Bonzy J: Early intensified chemotherapy with autologous bone marrow transplantation in first line treatment of poor risk non-seminomatous germ cell tumors. Eur Urol 1993;23:213-218.
8. Droz JP, Culine S, Biron P, Kramar A: High-dose chemotherapy in germ cell tumors. Ann Oncol 1996;7:997-1003.
9. Bokemeyer C, Schmoll HJ Treatment of advanced germ cell tumours by dose intensified chemotherapy with haematopoietic growth factors or peripheral blood stem cells (PBSC). Eur Urol 1993;23:223-230.
10. Bokemeyer C, Harstrick A, Metzner B, Beyer J, Rüther U, Berdel W, Casper J, Kührer I, Illiger JK, Kempf B, Föller A, Holstein K, Derigs HG, Schmoll HJ: Sequential high-dose VIP-chemotherapy plus peripheral stem cell (PBSC) support for advanced germ cell cancer. (abstract 259) Ann Oncol 1996;7 (suppl 5):55
11. Lampe H, Dearnaley DP, Price A, Mehta J, Powles R, Nicholls J, Horwich A: High-dose carboplatin and etoposide for salvage chemotherapy of germ cell tumours: Eur J Cancer 1995;31A:717-723
12. Beyer J, Kramar A, Mandanas R, Linkesch W, Greinix A, Droz JP, Pico JL, Diehl A, Bokemeyer C, Schmoll HJ, Nichols CR, Einhorn LH, Siegert W: High-dose chemotherapy as salvage treatment in germ cell tumors: A multivariate analysis of prognostic variables. J Clin Oncol 1996;14:2638-2645.
13. Bokemeyer C, Berger CC, Kuczyk MA, Schmoll HJ: Evaluation of long-term toxicity after chemotherapy for testicular cancel. J Clin Oncol 1996;14: 2923-2932.