Analysis of the butyrylcholinesterase gene and nearby chromosome 3 markers in Alzheimer disease

Human Molecular Genetics

Volumn 7, Issue 5, 1998, Pages 933-935

  Brindle, N ^e,f   Song, Y ^e,f   Rogaeva, E ^e,f   Premkumar, S ^a   Levesque, G ^e,f   Yu, G ^e,f   Ikeda, M ^e,f   Nishimura, M ^e,f   Paterson, A ^b   Sorbi, S ^c   Duara, R ^d   Farrer, L ^a   St George Hyslop, P ^e,f  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TORONTO   (Canada)

^c Dept of Neurology and Psychiatry ^*  (Italy)

^d MOUNT SINAI MEDICAL CENTER   (United States)

^e UNIVERSITY OF TORONTO   (Canada)

^f UNIVERSITY HEALTH NETWORK   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E; CHOLINESTERASE; ENZYME VARIANT;

ALLELE; ALZHEIMER DISEASE; ARTICLE; CHROMOSOME 3; FAMILIAL DISEASE; GENE FREQUENCY; GENETIC MARKER; HUMAN; PRIORITY JOURNAL;

AGED; ALLELES; ALZHEIMER DISEASE; APOLIPOPROTEIN E4; APOLIPOPROTEINS E; BUTYRYLCHOLINESTERASE; CHROMOSOMES, HUMAN, PAIR 3; FEMALE; GENE FREQUENCY; GENETIC MARKERS; HUMANS; MALE; MIDDLE AGED;

EID: 7144262433     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: 10.1093/hmg/7.5.933     Document Type: Article

References (19)

1. Bartels, C.F., Jensen, F.S., Lockridge, O., van der Spek, A.F.L., Rubinstein, H.M., Lubrano, T. and La Du, B.N. (1992) DNA mutation associated with the butyrylcholinesterase K-variant and its linkage to the atypical variant mutation and other polymorphic sites. Am. J. Hum. Genet., 50, 1086-1103.
2. Lehmann, D.J., Johnston, C. and Smith, A.D. (1997) Synergy between the genes for butyrylcholinesterase K variant and apolipoprotein E4 in late onset confirmed Alzheimer disease. Hum. Mol. Genet., 6, 1933-1936.
3. Jensen, F.S., Nielsen, L.R. and Schwartz, M. (1996) Detection of the plasma cholinesterase K variant by PCR using an amplification-created restriction site. Hum. Hered., 46, 26-31.
4. Breslow, N.E. and Day, N.E. (1980) The Analysis of Case Control Studies. Statistical Methods in Cancer Research, Vol. 1. Lyon: IARC Scientific Publications 32.
5. Saunders, A., Strittmatter, W.J., Schmechel, S. et al. (1993) Association of apoliprotein E allele ε4 with the late-onset familial and sporadic Alzheimer disease. Neurology, 43, 1467-1472.
6. Khachaturian, Z.S. (1985) Diagnosis of Alzheimer disease. Arch. Neurol., 42, 1097-1105.
7. McKhann, G., Drachman, D., Folstein, M., Katzman, R., Price, D. and Stadlan, E.M. (1984) Clinical diagnosis of Alzheimer disease: report of the NINCDS-ADRDA Work Group under the auspices of the Department of Health and Human Services Task force on Alzheimer Disease. Neurology. 34, 939-944.
8. Gearing, M., Mirra, S.S., Hedreen, J.C., Sumi, S.M., Hansen, L.A. and Heyman, A. (1995) The consortium to establish a registry for Alzheimer disease (CERAD). Part X. Neuropathologic confirmation of the clinical diagnosis of Alzheimer disease. Neurology, 45, 461-466.
9. Sherrington, R., Rogaev, E., Liang, Y. et al. (1995) Cloning of a gene bearing missense mutations in early onset familial Alzheimer's disease. Nature, 375, 754-760.
10. Rogaev, E.I., Sherrington, R., Rogaeva, E.A. et al. (1995) Familial Alzheimer's disease in kindreds with missense mutations in a novel gene on chromosome 1 related to the Alzheimer's disease type 3 gene. Nature, 376, 775-778.
11. Levy-Lahad, E. et al. (1995) A familial Alzheimer's disease locus on chromosome 1. Science, 269, 970-973.
12. Goate, A.M., Chartier-Harlin, M.-C., Mullan, M., Brown, J., Crawford, F., Fidani, L., Guiffra, L., Haynes, A. and Hardy, J.A. (1991) Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer disease. Nature, 349, 704-706.
13. Hendricks, M., van Duijn, C.M., Cras, P. et al. (1992) Presenile dementia and cerebral hemorrhage linked to a mutation at codon 692 of the B-amyloid precursor protein gene. Nature Genet., 1, 218-221.
14. Mullan, M.J., Crawford, F., Axelman, K., Houlden, H., Lilius, L., Winblad, B., Lannfelt, L. and Hardy, J. (1992) A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of B-amyloid. Nature Genet., 1, 345-347.
15. SAS User's Guide: Statistics. 1992, SAS Institute Inc., Cary, NC.
16. Kruglyak, L., Daly, M.J., Reeve-Daly, M.P. and Lander, E.S. (1996) Parametric and non-parametric linkage analysis: a unified multipoint approach. Am. J. Hum. Genet., 58, 1347-1363.
17. Farrer, L.A. and Stice, L. (1993) Susceptibility genes for familial Alzheimer's disease on chromosomes 19 and 21: a reality check. Genet. Epidemiol., 10, 425-430.
18. Farrer, L.A., Myers, R.H., Cupples, L.A., St George-Hyslop, P.H., Bird, T.D., Rossor, M.N. et al. (1990) Transmission and age-at-onset patterns in familial Alzheimer disease: evidence for heterogeneity. Neurology, 40, 395-403.
19. Ott, J. (1991) Analysis of Human Genetic Linkage. Johns Hopkins University Press, Baltimore, MD.