Bolus/infusional 5-fluorouracil and folinic acid. A report on two prospective, consecutive phase II studies with 5-fluorouracil dose escalation

British Journal of Cancer

Volumn 77, Issue 9, 1998, Pages 1480-1486

  Mackean, M J ^a   Cassidy, J ^a,b   Jodrell, D I ^a,c   Paul, J ^a   Reed, N S ^a   Canney, P A ^a   Yosef, H ^a   Habeshaw, T ^a   Robertson, A G ^a   McInnes, A ^a   Twelves, C J ^a  

^a BEATSON WEST OF SCOTLAND CANCER CENTRE   (United Kingdom)

^b ABERDEEN ROYAL INFIRMARY   (United Kingdom)

^c WESTERN GENERAL HOSPITAL   (United Kingdom)

Author keywords

5 FU; Folinic acid; Group sequential triangular test; Metastatic colorectal carcinoma

Indexed keywords

ALKALINE PHOSPHATASE; FLUOROURACIL; FOLIC ACID DERIVATIVE; FOLINIC ACID; PYRIMIDINE ANTAGONIST; SERUM ALBUMIN;

ADULT; ADVANCED CANCER; AGED; ARTICLE; BOLUS INJECTION; CANCER SURVIVAL; CLINICAL TRIAL; COHORT ANALYSIS; COLORECTAL CARCINOMA; CONTINUOUS INFUSION; DIARRHEA; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; LEUKOPENIA; MAJOR CLINICAL STUDY; MUCOSA INFLAMMATION; NAUSEA; PHASE 2 CLINICAL TRIAL; PRIORITY JOURNAL; PROSPECTIVE STUDY; VOMITING;

EID: 7144260393     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/bjc.1998.243     Document Type: Article

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