Increased intragraft IL-15 mRNA expression after liver transplantation

Clinical Transplantation

Volumn 12, Issue 3, 1998, Pages 212-218

  Baan, Carla C ^a   Niesters, Hubert G M ^a   Metselaar, Herold J ^a   Mol, Wendy M ^a   Loonen, Elisabeth H M ^a   Zondervan, Pieter E ^a   Tilanus, Huug W ^a   IJzermans, Jan M N ^a   Schalm, Solko W ^a   Weimar, Willem ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

Chemokines; IL 15; IL 2; mRNA; T cell activation

Indexed keywords

ASPARTATE AMINOTRANSFERASE; BILIRUBIN; INTERLEUKIN 15; INTERLEUKIN 2; MESSENGER RNA;

ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BILIRUBIN BLOOD LEVEL; CELL INTERACTION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GRAFT REJECTION; HISTOLOGY; HUMAN; HUMAN TISSUE; IMMUNE RESPONSE; LIVER BIOPSY; LIVER TRANSPLANTATION; MACROPHAGE; MALE; MESSENGER RNA SYNTHESIS; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION;

BIOPSY; ELECTROPHORESIS, AGAR GEL; FEMALE; GRAFT REJECTION; HUMANS; INTERLEUKIN-15; INTERLEUKIN-2; LIVER TRANSPLANTATION; MALE; POLYMERASE CHAIN REACTION; RNA, MESSENGER; T-LYMPHOCYTES; UP-REGULATION;

EID: 7144255541     PISSN: 09020063     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. HUBSCHER SG. Histological findings in liver allograft rejection-new insights into the pathogenesis of hepatocellular damage in liver allografts. Histopathology 1991: 180: 377.
2. MCCAUGHAN GW, DAVIES JW, WAUGH JA. A quantitative analysis of T lymphocyte populations in human liver allografts undergoing rejection. Hepatology 1990: 12: 1305.
3. BISHOP GA, ROKAHR KL, NAPOLI J, MCCAUGAN GW. Intragraft cytokine mRNA levels in human liver allograft rejection analyzed by reverse transcription and semiquantitative polymerase chain reaction amplification. Transplant Immunol 1993: 1: 253.
4. GORCZYNSKI RM, ADAMS RB, LEVY GA, CHUNG SW. Correlation of peripheral blood lymphocyte and intragraft cytokine mRNA expression with rejection in orthotopic liver transplantation. Surgery 1996: 120: 496.
5. COZENZA CA, SHIRWAN H, CRAMER DV, SHER L, PODESTA L, MAKOWKA L. Intragraft cytokine gene expression in human liver allografts. Liver Transplant Surg 1995: 1: 16.
6. BAAN CC, METSELAAR HJ, MOL WM, et al. Intragraft IL-4 mRNA expression is associated with down- regulation of liver graft rejection. Clin Transplant 1996: 10: 542.
7. MARTINEZ OM, KRAMS SM, STERNECK M, et al. Intragraft cytokine profile during human liver allograft rejection. Transplantation 1992: 53: 449.
8. STEIGER J, NICKERSON PW, STREURER W, MOSCOVITCH-LOPATIN M, STROM TB. IL-2 knockout recipient mice reject islet cell allografts. J Immunol 1995: 155: 489.
9. ROY-CHAUDHURY P, MANFRO RC, STEIGER J, MOSCOVITCH-LOPATIN M, STROM TB. IL-2 and IL-4 double knock-out mice reject islet allografts: a role for novel T-cell growth factors? Transplant Proc 1997: 29: 1083.
10. GRABSTEIN KH, EISENMAN J, SHANEBECK K, et al. Cloning of a T-cell growth factor that interacts with the β-chain of the Interleukin-2 receptor. Science 1994: 264 965.
11. CARSON WE, GIRI JG, LINDEMANN MJ, et al. Interleukin-15 is a novel cytokine which activates natural killer cells via components of the interleukin-2 receptor. J Exp Med 1994: 180: 1395.
12. YE W, DING-E YOUNG J, LIU C. Interleukin-15 induces the expression of mRNAs of cytolytic mediators and augments cytotoxic activities in primary murine lymphocytes. Cell Immunol 1996: 174: 54.
13. ARMITAGE RJ, MACDUFF BM, TSANG M, et al. IL-15 has stimulatory activity for the induction of B cell proliferation and differentiation. J Immunol 1995: 154: 483.
14. WILKINSON PC, LIEW FY. Chemoattraction of human blood T lymphocytes by interleukin-15. J Exp Med 1995: 181: 1255.
15. MCINNES IB, AL-MUGHALES J, FIELD M, et al. The role of IL-15 in T-cell migration and activation in rheumatoid arthritis. Nature Med 1996: 2: 175.
16. CARSON WE, CALIGIURI MA. Interleukin 15: A potential player during the innate immune response to infection. Exp Parasitol 1996: 84: 291.
17. PAVLAKIS M, STREHLAU J, LIPMAN M, SHAPIRO M, MASLINSKI W, STROM TB. Intragraft IL-15 transcripts are increased in human renal allograft rejection. Transplantation 1996: 62: 543.
18. SNOVER DC, FREESE DK, SHARP HL, BLOOMER JR, NAJARIAN JS, ASCHER NL Liver allograft rejection. An analysis of the use of biopsy in determining outcome of rejection. Am J Surg Pathol 1987: 11 (1): 1.
19. CHOMCZYNSKI P, SACCHI N. Single step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987: 162: 156.
20. NICKERSON P, STEURER W, STEIGER J, ZHENG X, STEELE AW, STROM TB. Cytokines and the Th1/Th2 paradigm in transplantation. Curr Opin Immunol 1994: 6: 757.
21. PICCOTTI JR, CHAN SY, VANBUSKIRK AM, EICHWALD EJ, BISHOP DK. Are Th2 helper T lymphocytes beneficial deleterious, or irrelevant in promoting allograft survival? Transplantation 1997: 63 (5): 619.
22. BAMFORD RN, TAGAYA Y, WALDMANN TA. Interleukin 15-what it does and how it is controlled. The Immunologist 1997: 5/2: 52.
23. CHAE DW, NOSAKA Y, STROM TB, MASLINSKI W. Distribution of IL-15 receptor alpha-chains on human peripheral blood mononuclear cells and effect of immunosuppressive drugs on receptor expression. J Immunol 1995: 157 (7): 2813
24. ADAMS DH, LLOYD AR. Chemokines: leucocyte recruitment and activation cytokines. Lancet 1997: 349: 490.
25. ADAMS DH, HUBSCHER S, FEAR J, JOHNSON J, SHAW S, AFFORD S. Hepatic expression of macrophage inflammatory protein-1α and macrophage inflammatory factor-1β after liver transplantation. Transplantation 1996: 61: 817.
26. SOLEZ K, RACUSEN LC, MARCUSSEN N, et al. Morphology of ischemic acute renal failure, normal function, and cyclosporin toxicity in cyclosporin-treated renal allograft recipients. Kidney Int 1993: 43: 1058.
27. HOFFMANN MW, WONIGEIT K, STEINHOFF G, HERZBECK H, FLAD HD, PICHLMAYR R. Production of cytokines (TNF-α, IL-1β) and endothelial cell activation in human liver allograft rejection Transplantation 1993: 55: 329.