Distribution of the B33 CTG repeat polymorphism in a subtype of schizophrenia

European Archives of Psychiatry and Clinical Neuroscience

Volumn 248, Issue 2, 1998, Pages 78-81

  Bengel, Dietmar ^a   Balling, Ursula ^a   Stöber, Gerald ^a   Heils, Armin ^a   Li, Shi Hua ^b   Ross, Cristopher A ^b   Jungkunz, Gerd ^c   Franzek, Ernst ^a   Beckmann, Helmut ^a   Riederer, Peter ^a   Lesch, Klaus Peter ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b JOHNS HOPKINS UNIVERSITY   (United States)

^c Bezirk Unterfranken   (Germany)

Author keywords

Anticipation; Association study; B33 CTG repeat locus; Periodic catatonia; Schizophrenia

Indexed keywords

ADULT; ARTICLE; CATATONIA; CHROMOSOME 3; CLINICAL ARTICLE; FEMALE; GENETIC POLYMORPHISM; HUMAN; HUMAN CELL; MALE; PRIORITY JOURNAL; SCHIZOPHRENIA; TRINUCLEOTIDE REPEAT;

ADULT; AGED; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 3; FEMALE; GENES, DOMINANT; GENETIC PREDISPOSITION TO DISEASE; GENETIC SCREENING; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; SCHIZOPHRENIA, CATATONIC; TRINUCLEOTIDE REPEATS;

EID: 7144227924     PISSN: 09401334     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004060050021     Document Type: Article

References (30)

1. American Psychiatric Association (1987) Diagnostic and statistical manual of mental disorders (DSM-III-R), 3rd edn, revised. American Psychiatric Press, Washington DC
2. Bassett AS, Honer WG (1994) Evidence for anticipation in schizophrenia. Am J Hum Genet 54: 864-870
3. Bates G, Lehrach H (1994) Trinucleotide repeat expansions and human genetic disease. BioEssays 16: 277-284
4. Franzek E, Beckmann H (1992) Schizophrenia: not a disease entity? A study of 57 long-term hospitalized chronic schizophrenics. Eur J Psychiatry 6: 97-108
5. Gaitonde EJ, Sivagnanasundaram S, Morris AG, McKenna PJ, Mollon JD, Hunt DM (1997) The number of triplet repeats in five brain-expressed loci with CAG repeats is not associated with schizophrenia. Schizophr Res 25: 111-116
6. Gorwood P, Leboyer M, Falissard B, Jay M, Rouillon F, Feingold J (1996) Anticipation in schizophrenia: new light on a controversial problem. Am J Psychiatry 153: 1173-1177
7. Haaf T, Sirugo G, Kidd KK, Ward DC (1996) Chromosomal localization of long trinucleotide repeats in the human genome by fluorescence in situ hybridization. Nat Genet 12: 183-185
8. La Spada AR, Paulson HL, Fischbeck KH (1994) Trinucleotide repeat expansion in neurological disease. Ann Neurol 36: 814-822
9. Leonhard K (1979) The classification of endogenous psychoses. Irvington, New York
10. Leonhard K (1980) Contradictory issues in the origin of schizophrenia. Br J Psychiatry 136: 437-444
11. Lesch KP, Stöber G, Balling U, Franzek E, Li SH, Ross CA, Newman M, Beckmann H, Riederer P (1994) Triplet repeats in clinical subtypes of schizophrenia: variation at the DRPLA (B37 CAG repeat) locus is not associated with periodic catatonia. J Neural Transm Genet 198: 153-157
12. Li SH, McInnis MG, Margolis RL, Antonarkis SE, Ross CA (1993) Novel triplet repeat containing genes in human brain: cloning, expression and length polymorphisms. Genomics 16: 572-579
13. Mandel JL (1993) Questions of expansion. Nat Genet 4: 8-9
14. Mclnnis MG, McMahon FJ, Chase GH, Simpson SG, Ross CA, DePaulo JR (1993) Anticipation of bipolar affective disorder. Am J Hum Genet 53: 385-390
15. Morris AG, Gaitonde E, McKenna PJ, Mollon JD, Hunt DM (1995) CAG repeat expansions and schizophrenia: association with disease in females and with early age-at-onset. Hum Mol Genet 4: 1957-1961
16. Morris-Rosendahl DJ, Burgert E, Uyanik G, Mayerova A, Duval F, Macher JP, Crocq MA (1997) Analysis of the CAG repeats in the SCA1 and B37 genes in schizophrenic and bipolar disorder patients: tentative association between B37 and schizophrenia. Am J Med Genet 74: 324-330
17. O'Donovan MC, Guy C, Craddock N, Bowen T, McKeon P, Macedo A, Maier W, Wildenauer D, Aschauer HN, Sorbi S, Feldman E, Mynett-Johnson L, Claffey E, Nacmias B, Valente J, Dourado A, Grassi E, Lenzinger E, Heiden AM, Moorhead S, Harrison D, Williams J, McGuffin P, Owen MJ (1996) Confirmation of association between expanded CAG/CTG repeats and both schizophrenia and bipolar disorder. Psychol Med 26: 1145-1153
18. Petronis A, Kennedy JL (1995) Unstable genes - unstable mind? Am J Psychiatry 152: 164-172
19. Propping P (1989) Psychiatrische Genetik. Springer, Berlin Heidelberg New York
20. Ross CA, McInnis MG, Margolis RL, Li SH (1993) Genes with triplet repeats: candidate mediators of neuropsychiatric disorders. Trends Neurosci 16: 264-272
21. Rubinsztein DC, Leggo J, Goodburn S, Barton DE, Ferguson-Smith MA, Ross CA, Li SH, Lofthouse R, Crow TH, Delisi TH (1994a) B 37 repeats are normal in most schizophrenic patients (letter). Br J Psychiatry 164: 851-852
22. Rubinsztein DC, Leggo J, Goodburn S, Crow TJ, Lofthouse R, Barton DE, Ferguson-Smith MA (1994b) Study of the Huntington disease (HD) gene CAG repeats in schizophrenic patients shows overlap of the normal and HD affected ranges but absence of correlation with schizophrenia. J Med Genet 31: 690-693
23. Sasaki T, Billet E, Petronis A, Ying D, Parsons T, Macciardi FM, Meltzer HY, Lieberman J, Joffe RT, Ross CA, McInnis MG (1996) Psychosis and genes with trinucleotide repeat polymorphism. Hum Genet 97: 244-246
24. Schalling M, Hudson TJ, Buetow KW, Housman DE (1993) Direct detection of novel expanded trinucleotide repeals in the human genome. Nat Genet 7: 135-139
25. Scharfetter C, Nuesperli M (1980) The group of schizophrenias, schizoaffective psychoses, and affective disorders. Schizophr Bull 6: 586-591
26. Slater E, Cowie V (1971) The genetics of mental disorders. Oxford Press, London
27. St. Clair D (1994) Expanded CAG trinucleotide repeat of Huntington's disease gene in a patient with schizophrenia and normal striatal histology. J Med Genet 31: 658-659
28. Stöber G, Franzek E, Lesch KP, Beckmann H (1995) Periodic catatonia: a schizophrenic subtype with major gene effect and anticipation. Eur Arch Psychiatry Neurol Sci 245: 135-141
29. Thibaut F, Martinez M, Petit M, Jay M, Campion D (1995) Further evidence for anticipation in schizophrenia. Psychiatry Res 59: 25-33
30. Yaw J, Myles-Worsley M, Hoff M, Holik J, Freedman R, Byerley W, Coon H (1996) Anticipation in multiplex schizophrenia pedigrees. Psychiatr Genet 6: 7-11