Local anesthetics structure-dependently interact with anionic phospholipid membranes to modify the fluidity

Chemico-Biological Interactions

Volumn 183, Issue 1, 2010, Pages 19-24

  Tsuchiya, Hironori ^a   Ueno, Takahiro ^a   Mizogami, Maki ^a   Takakura, Ko ^a  

^a ASAHI UNIVERSITY   (Japan)

Author keywords

Anionic phospholipids; Cardiotoxicity; Fluidity modification; Local anesthetics; Membrane interaction; Structure dependence

Indexed keywords

ANION; BUPIVACAINE; CARDIOLIPIN; CHOLESTEROL; LIDOCAINE; LIPOSOME; LOCAL ANESTHETIC AGENT; PHOSPHATIDIC ACID; PHOSPHATIDYLGLYCEROL; PHOSPHATIDYLSERINE; PHOSPHOLIPID; PRILOCAINE; ROPIVACAINE;

ARTICLE; CARDIOTOXICITY; CELL MEMBRANE FLUIDITY; CELL MEMBRANE POTENTIAL; CONTROLLED STUDY; DRUG POTENCY; HEART MITOCHONDRION; HEART MUSCLE CELL; HYDROPHOBICITY; LIPID BILAYER; LIPID COMPOSITION; MEMBRANE VESICLE; MITOCHONDRIAL MEMBRANE; PHOSPHOLIPID MEMBRANE;

AMIDES; ANESTHETICS, LOCAL; ANIONS; BUPIVACAINE; CARDIOLIPINS; FLUORESCENCE POLARIZATION; LIDOCAINE; LIPID BILAYERS; MEMBRANE FLUIDITY; PHOSPHOLIPIDS; PRILOCAINE; UNILAMELLAR LIPOSOMES;

EID: 71349083368     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2009.10.006     Document Type: Article

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