Late-onset rheumatoid arthritis and late-onset spondyloarthritis

Clinical and Experimental Rheumatology

Volumn 27, Issue 4 SUPPL. 55, 2009, Pages

  Olivieri, Ignazio ^a   Pipitone, Nicolò ^b   D'Angelo, Salvatore ^a   Padula, Angela ^a   Salvarani, Carlo ^b  

^a SAN CARLO HOSPITAL   (Italy)

^b Rheumatology Unit   (Italy)

Author keywords

Ankylosing spondylitis; Elderly; Late onset; Psoriatic arthritis; Rheumatoid arthritis; Spondyloarthritis; Undifferentiated spondyloarthritis

Indexed keywords

ALPHA 2 GLOBULIN; ANTIINFLAMMATORY AGENT; C REACTIVE PROTEIN; CYCLIC CITRULLINATED PEPTIDE ANTIBODY; CYCLOOXYGENASE 2 INHIBITOR; DISEASE MODIFYING ANTIRHEUMATIC DRUG; ETANERCEPT; GLUCOCORTICOID; HLA B27 ANTIGEN; HLA DR3 ANTIGEN; HYDROXYCHLOROQUINE; INTERLEUKIN 1BETA; INTERLEUKIN 6; LEFLUNOMIDE; METHOTREXATE; NONSTEROID ANTIINFLAMMATORY AGENT; PENICILLAMINE; PLACEBO; RHEUMATOID FACTOR; SALAZOSULFAPYRIDINE;

ANKYLOSING SPONDYLITIS; CLINICAL TRIAL; DIFFERENTIAL DIAGNOSIS; DISEASE COURSE; DISEASE SEVERITY; ECHOGRAPHY; EDEMA; ENTERITIS; ENTHESITIS; ERYTHROCYTE SEDIMENTATION RATE; GERIATRIC DISORDER; GOLD THERAPY; HUMAN; INCIDENCE; INFLAMMATION; JOINT ASPIRATION; JOINT RADIOGRAPHY; JOINT SCINTISCANNING; LIMB SWELLING; LOW DRUG DOSE; METACARPOPHALANGEAL JOINT; MORTALITY; NUCLEAR MAGNETIC RESONANCE IMAGING; ONSET AGE; PATIENT COMPLIANCE; POLYARTHRITIS; PRACTICE GUIDELINE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN BLOOD LEVEL; PROXIMAL INTERPHALANGEAL JOINT; PSORIATIC ARTHRITIS; REACTIVE ARTHRITIS; REVIEW; RHEUMATIC POLYMYALGIA; RHEUMATOID ARTHRITIS; SEROLOGY; SPONDYLARTHRITIS; SUBCUTANEOUS NODULE; SWELLING; SYNOVITIS; WRIST;

AGE OF ONSET; AGED; ANTIRHEUMATIC AGENTS; ARTHRITIS, PSORIATIC; ARTHRITIS, RHEUMATOID; DIAGNOSIS, DIFFERENTIAL; HUMANS; MIDDLE AGED; PRACTICE GUIDELINES AS TOPIC; SPONDYLITIS, ANKYLOSING;

EID: 71249147670     PISSN: 0392856X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (94)

1. DEAL CL, MEENAN RF, GOLDENBERG DL et al.: The clinical features of elderly-onset rheumatoid arthritis. A comparison with younger-onset disease of similar duration. Arthritis Rheum 1985; 28: 987-994
2. VAN SCHAARDENBURG D, BREEDVELD FC: Elderly-onset rheumatoid arthritis. Semin Arthritis Rheum 1994; 23: 367-378
3. TERKELTAUB R, ESDAILE J, DECARY F, TANNENBAUM H: A clinical study of older age rheumatoid arthritis with comparison to a younger onset group. J Rheumatol 1983; 10: 418-424
4. SALVARANI C, ZIZZI F, MACCHIONI PL et al.: [A clinical study on elderly-onset rheumatoid arthritis. Comparison with a group of patients with disease onset before age 60 years]. [Italian]. Il Reumatologo 1990; 3: 107-112
5. EHRLICH GE, KATZ WA, COHEN SH: Rheumatoid arthritis in the aged. Geriatrics 1970; 25: 103-113
6. PIPITONE N, PITZALIS C: [Arthritides in the elderly]. [Italian]. Recenti Prog Med 2004; 95: 432-442
7. CECIL RL, KAMMERER WH: Rheumatoid arthritis in the aged. Am J Med 1951; 10: 439-45.
8. OLIVIERI I, PALAZZI C, PERUZ G, PADULA A: Management issues with elderly-onset rheumatoid arthritis: an update. Drugs Aging 2005; 22: 809-822 (Pubitemid 41539946)
9. BAJOCCHI G, LA CORTE R, LOCAPUTO A, GOVONI M, TROTTA F: Elderly onset rheumatoid arthritis: clinical aspects. Clinical Exp Rheumatol 2000; 18 (Suppl. 20): S49-50.
10. PUNZI L, BERTAZZOLO N, PIANON M, RIZZI E, ROSSINI P, TODESCO S: Synovial fluid levels of proinflammatory interleukins and their inter-relationships in elderly vs younger onset rheumatoid arthritis. Aging (Milano) 1996; 8: 277-281
11. CHEN DY, HSIEH TY, CHEN YM, HSIEH CW, LAN JL, LIN FJ: Proinflammatory cytokine profiles of patients with elderly-onset rheumatoid arthritis: a comparison with younger-onset disease. Gerontology 2009; 55: 250-258
12. CORRIGAN AB, ROBINSON RG, TERENTY TR, DICK-SMITH JB, WALTERS D: Benign rheumatoid arthritis of the aged. Br Med J 1974; 1: 444-446
13. TURKCAPAR N, DEMIR O, ATLI T et al.: Late onset rheumatoid arthritis: clinical and laboratory comparisons with younger onset patients. Arch Gerontol Geriatr 2006; 42: 225-231
14. BATHON JM, FLEISCHMANN RM, VAN DER HEIJDE D et al.: Safety and efficacy of etanercept treatment in elderly subjects with rheumatoid arthritis. J Rheumatol 2006; 33: 234-243 (Pubitemid 43209297)
15. GLENNAS A, KVIEN TK, ANDRUP O, KARSTENSEN B, MUNTHE E: Recent onset arthritis in the elderly: a 5 year longitudinal observational study. J Rheumatol 2000; 27: 101-108
16. HANTZSCHEL H, BIRD HA, SEIDEL W et al.: Polymyalgia rheumatica and rheumatoid arthritis of the elderly: a clinical, laboratory, and scintigraphic comparison. Ann Rheum Dis 1991; 50: 619-622
17. CECCATO F, ROVERANO S, BARRIONUEVO A, RILLO O, PAIRA S: The role of anticyclic citrullinated peptide antibodies in the differential diagnosis of elderly-onset rheumatoid arthritis and polymyalgia rheumatica. Clin Rheumatol 2006; 25: 854-857 (Pubitemid 44473152)
18. LOPEZ-HOYOS M, RUIZ DE ALEGRIA C, BLANCO R et al.: Clinical utility of anti-CCP antibodies in the differential diagnosis of elderly-onset rheumatoid arthritis and polymyalgia rheumatica. Rheumatology (Oxford) 2004; 43: 655-657
19. PARODI M, GARLASCHI G, SILVESTRI E, CIMMINO MA: Magnetic resonance imaging in the differential diagnosis between polymyalgia rheumatica and elderly onset rheumatoid arthritis. Clin Rheumatol 2006; 25: 402-403
20. SALVARANI C, CANTINI F, OLIVIERI I et al.: Proximal bursitis in active polymyalgia rheumatica. Ann Intern Med 1997; 127: 27-31.
21. CANTINI F, SALVARANI C, NICCOLI L et al.: Fat suppression magnetic resonance imaging in shoulders of patients with polymyalgia rheumatica. J Rheumatol 2004; 31: 120-124
22. CANTINI F, SALVARANI C, OLIVIERI I et al.: Shoulder ultrasonography in the diagnosis of polymyalgia rheumatica: a case-control study. J Rheumatol 2001; 28: 1049-1055
23. MORI S, KOGA Y, ITO K: Clinical characteristics of polymyalgia rheumatica in Japanese patients: evidence of synovitis and extracapsular inflammatory changes by fat suppression magnetic resonance imaging. Mod Rheumatol 2007; 17: 369-375
24. SALVARANI C, CANTINI F, OLIVIERI I: Distal musculoskeletal manifestations in polymyalgia rheumatica. Clin Exp Rheumatol 2000; 18 (4 Suppl. 20): S51-2.
25. PEASE CT, HAUGEBERG G, MONTAGUE B et al.: Polymyalgia rheumatica can be distinguished from late onset rheumatoid arthritis at baseline: results of a 5-year prospective study. Rheumatology (Oxford) 2009; 48: 123-127
26. PEASE CT, BHAKTA BB, DEVLIN J, EMERY P: Does the age of onset of rheumatoid arthritis influence phenotype?: a prospective study of outcome and prognostic factors. Rheumatology (Oxford) 1999; 38: 228-234
27. CAPORALI R, MONTECUCCO C, EPIS O, BOBBIO-PALLAVICINI F, MAIO T, CIMMINO MA: Presenting features of polymyalgia rheumatica (PMR) and rheumatoid arthritis with PMR-like onset: a prospective study. Ann Rheum Dis 2001; 60: 1021-1024
28. HEALEY LA: Polymyalgia rheumatica and seronegative rheumatoid arthritis may be the same entity. J Rheumatol 1992; 19: 270-272
29. SALVARANI C, MACCHIONI P, MANTOVANI W, PORTIOLI I: Polymyalgia rheumatica and seronegative rheumatoid arthritis: some considerations based on a northern Italian population. J Rheumatol 1993; 20: 756-757
30. GONZALEZ-GAY MA, HAJEER AH, DABABNEH A et al.: Seronegative rheumatoid arthritis in elderly and polymyalgia rheumatica have similar patterns of HLA association. J Rheumatol 2001; 28: 122-125
31. COACCIOLI S, PINOCA F, GIULIANI M, LANDUCCI P, SABATINI C, PUXEDDU A: Definition of adult-onset rheumatoid arthritis from elderly-onset rheumatoid arthritis by studying T-lymphocyte subpopulations, their soluble receptors and soluble receptor of interleukin-2. Clin Ter 2007; 158: 303-306
32. CUTOLO M, MONTECUCCO CM, CAVAGNA L et al.: Serum cytokines and steroidal hormones in polymyalgia rheumatica and elderly-onset rheumatoid arthritis. Ann Rheum Dis 2006; 65: 1438-1443
33. BIRD HA, ESSELINCKX W, DIXON AS, MOWAT AG, WOOD PH: An evaluation of criteria for polymyalgia rheumatica. Ann Rheum Dis 1979; 38: 434-439
34. TAGGART AJ, MCDERMOTT B, DELARGY M et al.: The pharmacokinetics of sulphasalazine in young and elderly patients with rheumatoid arthritis. Scand J Rheumatol 1987; 64 (Suppl.): 29-36.
35. KEAN WF, BELLAMY N, BROOKS PM: Gold therapy in the elderly rheumatoid arthritis patient. Arthritis Rheum 1983; 26: 705-711
36. BIASI D, CARLETTO A, CARAMASCHI P, BAMBARA LM: [Treatment of rheumatoid arthritis of senile onset with methotrexate] [Italian). Recenti Prog Med 1995; 86: 472-475
37. NURCHIS P, SALVARANI C, ZIZZI F et al.: Rheumatoid arthritis in the elderly: frequency of side effects of parenteral and oral chrysotherapy. Eur J Inter Med 1994; 5: 1-7.
38. TUTUNCU Z, REED G, KREMER J, KAVANAUGH A: Do patients with older-onset rheumatoid arthritis receive less aggressive treatment? Ann Rheum Dis 2006; 65: 1226-1229
39. MAVRAGANI CP, MOUTSOPOULOS HM: Rheumatoid arthritis in the elderly. Exp Gerontol 1999; 34: 463-471
40. WASSENBERG S, RAU R, STEINFELD P, ZEIDLER H: Very low-dose prednisolone in early rheumatoid arthritis retards radiographic progression over two years: a multicenter, double-blind, placebo-controlled trial. Arthritis Rheum 2005; 52: 3371-3380
41. KIRWAN JR: The effect of glucocorticoids on joint destruction in rheumatoid arthritis. The Arthritis and Rheumatism Council Low-Dose Glucocorticoid Study Group. N Engl J Med 1995; 333: 142-146
42. KEAN WF, ANASTASSIADES TP, DWOSH IL, FORD PM, KELLY WG, DOK CM: Efficacy and toxicity of D-penicillamine for rheumatoid disease in the elderly. J Am Geriatr Soc 1982; 30: 94-100. (Pubitemid 12179858)
43. DROSOS A: Methotrexate intolerance in elderly patients with rheumatoid arthritis: what are the alternatives? Drugs Aging 2003; 20: 723-736
44. KHAN MA, VAN DER LINDEN SM: A wider spectrum of spondyloarthropathies. Semin Arthritis Rheum 1990; 20: 107-113
45. AMOR B, DOUGADOS M, MIJIYAWA M: [Critères de classification des spondylarthropathies] (French). Rev Rhum 1990; 57: 85-89
46. DOUGADOS M, VAN DER LINDEN S, JUHLIN R et al.: The European Spondylarthropathy Study Group preliminary criteria for the classification of spondylarthropathy. Arthritis Rheum 1991; 34: 1218-1227
47. OLIVIERI I, VAN TUBERGEN A, SALVARANI C, VAN DER LINDEN S: Seronegative spondyloarthritides. Best Pract Res Clin Rheumatol 2002; 16: 723-739
48. TOUSSIROT E, WENDLING D: Late-onset ankylosing spondylitis and related spondyloarthropathies. Clinical and radiological characteristics and pharmacological treatment options. Drugs Aging 2005; 22: 451-469
49. BENNETT PH, BURCH TA: Population studies of rheumatic diseases. Amsterdam: Excerpta Medica Foundation 1968: 456-457
50. VAN DER LINDEN S, VALKENBURG HA, CATS A: Evaluation of diagnostic criteria for ankylosing spondylitis. A proposal for modification of the New York criteria. Arthritis Rheum 1984; 27: 361-368
51. VAN DER LINDEN SM, VALKENBURG HA, DE JONGH BM, CATS A: The risk of developing ankylosing spondylitis in HLA-B27 positive individuals. A comparison of relatives of spondylitis patients with the general population. Arthritis Rheum 1984; 27: 241-249
52. DUBOST JJ, SAUVEZIE B: Actualités des rhumatismes inflammatoires du sujet âgé. Rev Rhum Mal Osteoartic 1992; 59 (6 bis): S37-42.
53. RD: Ankylosing spondylitis in Rochester, Minnesota, 1935-1989. Is the epidemiology changing? Arthritis Rheum 1992; 35: 1476-1482
54. FELDTKELLER E, BRUCKEL J, KHAN MA: Scientific contributions of ankylosing spondylitis patient advocacy groups. Curr Opin Rheumatol 2000; 12: 239-247
55. FELDTKELLER E, KHAN MA, VAN DER HEIJDE D, VAN DER LINDEN S, BRAUN J: Age at disease onset and diagnosis delay in HLA-B27 negative vs. positive patients with ankylosing spondylitis. Rheumatol Int 2003; 23: 61-66
56. DUBOST JJ, SAUVEZIE B: Late onset peripheral spondyloarthropathy. J Rheumatol 1989; 16: 1214-1217
57. DUBOST JJ, RISTORI JM, ZMANTAR C, SAUVEZIE B: [Rhumatismes séronégatifs a début tardif: Fréquence et atypies des spondylarthropathies] [French]. Rev Rhum Mal Osteoartic 1991; 58: 577-584
58. OLIVIERI I, ORANGES GS, SCONOSCIUTO F, PADULA A, RUJU GP, PASERO G: Late onset peripheral seronegative spondyloarthropathy: report of two additional cases. J Rheumatol 1993; 20: 390-393
59. OLIVIERI I, PADULA A, PIERRO A, FAVARO L, ORANGES GS, FERRI S: Late onset undifferentiated seronegative spondylarthropathy. J Rheumatol 1995, 22: 899-903.
60. CAPLANNE D, TUBACH F, LE PARC JM: Late onset spondylarthropathy: Clinical and biological comparison with early onset patients. Ann Rheum Dis 1997; 56: 176-179
61. OLIVIERI I, SALVARANI C, CANTINI F, CIANCIO G, PADULA A: Ankylosing spondylitis and undifferentiated spondyloarthropathies: a clinical review and description of a disease subset with older age at onset. Curr Opin Rheumatol 2001; 13: 280-284
62. OLIVIERI I, PADULA A, CIANCIO G, CANTINI F, SALVARANI C, GONZALEZ-GAY MA: Late onset HLA-B27-positive undifferentiated spondyloarthropathy: a new series of 20 patients. Arthritis Rheum 2001; 44 (Suppl.): S94.
63. MCCARTY DJ, O'DUFFY JD, PEARSON L, HUNTER JB: Remitting seronegative symmetrical synovitis with pitting edema. RS3PE syndrome. JAMA 1985; 254: 2763-2767
64. RUSSELL EB, HUNTER JB, PEARSON L, MCCARTY DJ: Remitting seronegative, symmetrical synovitis with pitting edema - 13 additional cases. J Rheumatol 1990; 17: 633-639
65. OLIVIERI I, PADULA A, FAVARO L, PIERRO A, ORANGES GS, FERRI S: Dactylitis with pitting edema of the hand in longstanding ankylosing spondylitis. Clin Rheumatol 1995; 14: 701-704
66. KOEGER AC, KARMOCHKINE M, CHAÏBI P: RS3PE syndrome associated with advanced ankylosing spondylitis. J Rheumatol 1995; 22: 375-376
67. KAIPIAINEN-SEPPÄNEN O: Incidence of psoriatic arthritis in Finland. Br J Rheumatol 1996; 35: 1289-1291
68. PUNZI L, PIANON M, ROSSINI P, SCHIAVON F, GAMBARI PF: Clinical and laboratory manifestations of elderly onset psoriatic arthritis: A comparison with younger onset disease. Ann Rheum Dis 1999; 58: 226-229
69. SALVARANI C, CANTINI F, OLIVIERI I et al.: Isolated peripheral enthesitis and/or dactylitis: A subset of psoriatic arthritis. J Rheumatol 1997; 24: 1106-1110
70. CANTINI, SALVARANI C, OLIVIERI I et al.: Distal extremity swelling with pitting edema in psoriatic arthritis: A case-control study. Clin Exp Rheumatol 2001; 19: 291-296 (Pubitemid 32529822)
71. LÓPEZ-MONTILLA MD, GONZÁLEZ J, MARTÍNEZ FG, FERNÁNDEZ-MORENO JR, COLLANTES E: Clinical features of late onset psoriatic arthritis. Exp Gerontol 2002; 37: 441-443 (Pubitemid 34073562)
72. KAY LJ, WALKER DJ: Late onset spondyloarthropathy: comparison with early onset patients. Ann Rheum Dis 1997; 56: 572.
73. OLIVIERI I, SALVARANI C, CANTINI F: Remitting distal extremity swelling with pitting edema: A distinct syndrome or a clinical feature of different inflammatory rheumatic diseases? J Rheumatol 1997; 24: 249-252
74. OLIVIERI I, SALVARANI C, CANTINI F: RS3PE syndrome: an overview. Clin Exp Rheumatol 2000; 18 (Suppl. 20): 53-55
75. SALVARANI C, GABRIEL S, HUNDER GG: Distal extremity swelling with pitting edema in polymyalgia rheumatica. Report on nineteen cases. Arthritis Rheum 1996; 39: 73-80.
76. SALVARANI C, CANTINI F, MACCHIONI P et al.: Distal musculoskeletal manifestations in polymyalgia rheumatica: A prospective followup study. Arthritis Rheum 1998; 41: 1221-1226
77. SALVARANI C, HUNDER GG: Musculoskeletal manifestations in a population-based cohort of patients with giant cell arteritis. Arthritis Rheum 1999; 42: 1259-1266 (Pubitemid 29268964)
78. CANTINI F, SALVARANI C, OLIVIERI I et al.: Remitting sieronegative symmetrical synovitis with pitting oedema (RS3PE) syndrome: A prospective follow up and magnetic resonance imaging study. Ann Rheum Dis 1999; 58: 230-236
79. GONZÁLEZ-GAY MA, GARCÍA-PORRÚA C, SALVARANI C, OLIVIERI I, HUNDER GG: Polymyalgia manifestations in different conditions mimicking polymyalgia rheumatica. Clin Exp Rheumatol 2000; 18: 755-759
80. OLIVIERI I, GARCIA-PORRUA C, PADULA A, CANTINI F, SALVARANI C, GONZALEZ-GAY MA: Late onset undifferentiated spondyloarthritis presenting with polymyalgia rheumatica features: description of seven cases. Rheumatol Int 2007; 27: 927-933
81. OLIVIERI I, BRANDI G, PADULA A et al.: Lack of association with spondyloarthitis and the HLA-B27 in Italian patients with Whipple's disease. J Rheumatol 2001; 28: 1294-1297
82. CANTINI F, NICCOLI L, OLIVIERI I et al.: Remitting distal lower extremity swelling with pitting oedema in acute sarcoidosis. Ann Rheum Dis 1997; 56: 565-566
83. IKE RW, BLAIVAS M: Corticosteroid responsive puffy hands and occult vasculitis neuropathy: RS3PE plus? J Rheumatol 1993: 20: 205-206
84. SCHAEVERBEKE T, FATOUT E, MARCÉ S et al.: Remitting seronegative symmetrical synovitis with pitting oedema: disease or syndrome? Ann Rheum Dis 1995; 54: 681-684
85. BILLEY T, NAVAUX F, LASSOUED S: Remitting seronegative symmetrical synovitis with pitting edema (RS3PE) as the first manifestation of periarteritis nodosa. Report of a case. Rev Rheum [Engl ed] 1995; 62: 53-54
86. GUMÁ M, CASADO E, TENA X, OLIVÉ A: RS3PE: Six years later. Ann Rheum Dis 1999; 58: 722-723
87. MCCARTY DJ: Clinical picture of rheumatoid arthritis. Arthritis and Allied Conditions, 12th edition. Edited by MCCARTY DJ, KOOPMAN WJ. MALVERN, PA: Lea and Febiger; 1993: n781-809.
88. MAGY N, MICHEL F, AUGE B, TOUSSIROT E, WENDLING D: Amyloid arthropathy revealed by RS3PE syndrome. Joint Bone Spine 2000; 67: 475-477
89. PITTAU E, PASSIU G, MATHIEU A: Remitting asymmetrial pitting oedema in systemic lupus erythematosus: two cases studied with magnetic resonance imaging. Joint Bone Spine 2000; 67: 544-549
90. CANTINI F, SALVARANI C, OLIVIERI I: Paraneoplastic remitting seronegative symmetrical synovitis with pitting edema. Clin Exp Rheumatol 1999; 17: 741-744
91. OLIVIERI I, D'ANGELO S, PALAZZI C, PADULA A, MADER R, KHAN MA: Diffuse idiopathic skeletal hyperorostosis: a condition that needs to be differentiated from spondyloarthritis. Curr Rheumatol Rep (in press).
92. ZOCHLING J, VAN DER HEIJDE D, BURGOS-VARGAS R et al.: ASAS/EULAR recommendations for the management of ankylosing spondylitis. Ann Rheum Dis 2006; 65: 442-52
93. RICHLIN CT, KAVANAUGH A, GLADMAN DD et al.: Treatment recommendations for psoriatic arthritis. Ann Rheum Dis 2009; 68: 1387-94.
94. OLIVIERI I, D'ANGELO S, PALAZZI C, PADULA A: Treatment strategies for early psoriatic arthritis. Expert Opin Pharmacother 2009; 10: 271-282