Outcomes after liver transplant in patients aged 70 years or older compared with those younger than 60 years

Mayo Clinic Proceedings

Volumn 84, Issue 11, 2009, Pages 973-978

  Aduen, Javier F ^a   Sujay, Bangarulingam ^a   Dickson, Rolland C ^a   Heckman, Michael G ^a   Hewitt, Winston R ^a   Stapelfeldt, Wolf H ^a   Steers, Jeffrey L ^a   Harnois, Denise M ^a   Kramer, David J ^a  

^a MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BILIRUBIN; CREATININE; SERUM ALBUMIN;

ADULT; AGED; ALBUMIN BLOOD LEVEL; ARTICLE; BILIRUBIN BLOOD LEVEL; BRAIN DISEASE; CARDIOGENIC SHOCK; CARDIOVASCULAR DISEASE; CATHETER INFECTION; CEREBROVASCULAR ACCIDENT; CHOLANGITIS; COMORBIDITY; COMPARATIVE STUDY; CONTROL GROUP; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DEATH; DEMOGRAPHY; DIABETES MELLITUS; ERYTHROCYTE TRANSFUSION; FEMALE; FLUID THERAPY; FOLLOW UP; GRAFT FAILURE; GRAFT REJECTION; GROUPS BY AGE; HEART ARRHYTHMIA; HEART INFARCTION; HUMAN; HYPERLIPIDEMIA; INTERNATIONAL NORMALIZED RATIO; KIDNEY FAILURE; LIVER GRAFT; LIVER TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; MORTALITY; NEOPLASM; PERITONITIS; PEROPERATIVE CARE; PNEUMONIA; POSTOPERATIVE CARE; POSTOPERATIVE COMPLICATION; POSTOPERATIVE PERIOD; RISK FACTOR; SEIZURE; WOUND INFECTION;

ACADEMIC MEDICAL CENTERS; AGE FACTORS; AGED; AGED, 80 AND OVER; CASE-CONTROL STUDIES; CAUSE OF DEATH; CONFIDENCE INTERVALS; FEMALE; FOLLOW-UP STUDIES; GERIATRIC ASSESSMENT; GRAFT REJECTION; GRAFT SURVIVAL; HOSPITAL MORTALITY; HUMANS; KAPLAN-MEIER ESTIMATE; LIVER FUNCTION TESTS; LIVER TRANSPLANTATION; MALE; MIDDLE AGED; MINNESOTA; POSTOPERATIVE COMPLICATIONS; PROBABILITY; RETROSPECTIVE STUDIES; RISK ASSESSMENT; STATISTICS, NONPARAMETRIC; SURGICAL WOUND INFECTION; TREATMENT OUTCOME;

EID: 71249134040     PISSN: 00256196     EISSN: None     Source Type: Journal    
DOI: 10.4065/84.11.973     Document Type: Article

References (22)

1. United Network for Organ Sharing. UNOS Web site. www.unos.org/. Accessed August 27, 2009.
2. U.S. Census Bureau. 2008 national population projections. www.census.gov/population/www/projections/2008projections.html. Accessed August 27, 2009.
3. Stieber AC, Gordon RD, Todo S, et al. Liver transplantation in patients over sixty years of age. Transplantation. 1991;51(1):271-273.
4. Pirsch JD, Kalayoglu M, D'Alessandro AM, et al. Orthotopic liver transplantation in patients 60 years of age and older. Transplantation. 1991;51(2):431-433.
5. Emre S, Mor E, Schwartz ME, et al. Liver transplantation in patients beyond age 60. Transplant Proc. 1993;25(1, pt 2):1075-1076. (Pubitemid 23078902)
6. Scheiner P, Emre S, Guy SR, Min A, Schwartz ME, Miller CM. The older liver transplant candidate: what are the limits? Liver Transpl Surg. 1996;2(5) (suppl 1):9-11. (Pubitemid 26303907)
7. Filipponi F, Roncella M, Boggi U, et al. Liver transplantation in recipients over 60. Transplant Proc. 2001;33(1-2):1465-1466.
8. Cross TJ, Antoniades CG, Muiesan P, et al. Liver transplantation in patients over 60 and 65 years: an evaluation of long-term outcomes and survival. Liver Transpl. 2007;13(10):1382-1388. (Pubitemid 47629570)
9. Rudich S, Busuttil R. Similar outcomes, morbidity, and mortality for orthotopic liver transplantation between the very elderly and the young. Transplant Proc. 1999;31(1-2):523-525. (Pubitemid 29127556)
10. Safdar K, Neff GW, Montalbano M, et al. Liver transplant for the septuagenarians: importance of patient selection. Transplant Proc. 2004;36(5):1445-1448. (Pubitemid 38903000)
11. Lipshutz GS, Hiatt J, Ghobrial RM, et al. Outcome of liver transplantation in septuagenarians: a single-center experience. Arch Surg. 2007;142(8):775-781. (Pubitemid 47295742)
12. Zetterman RK, Belle SH, Hoofnagle JH, et al. Age and liver transplantation: a report of the Liver Transplantation Database. Transplantation. 1998;66(4):500-506. (Pubitemid 28415378)
13. Adam R, Cailliez V, Majno P, et al. Normalised intrinsic mortality risk in liver transplantation: European Liver Transplant Registry study [published correction appears in Lancet. 2001;367(9264):1296]. Lancet. 2000;356(9230):621- 627.
14. Levy MF, Somasundar PS, Jennings LW, et al. The elderly liver transplant recipient: a call for caution. Ann Surg. 2001;233(1):107-113. (Pubitemid 32042780)
15. Garcia CE, Garcia RF, Mayer AD, Neuberger J. Liver transplantation in patients over sixty years of age. Transplantation. 2001;72(4):679-684. (Pubitemid 32802753)
16. Herrero JI, Lucena JF, Quiroga J, et al. Liver transplant recipients older than 60 years have lower survival and higher incidence of malignancy. Am J Transplant. 2003;3(11):1407-1412. (Pubitemid 37288086)
17. Collins BH, Pirsch JD, Becker YT, et al. Long-term results of liver transplantation in older patients 60 years of age and older. Transplantation. 2000;70(5):780-783.
18. Neuberger J, James O. Guidelines for selection of patients for liver transplantation in the era of donor-organ shortage. Lancet. 1999;354(9190):1636- 1639. (Pubitemid 29515965)
19. Keswani RN, Ahmed A, Keeffe EB. Older age and liver transplantation: a review. Liver Transpl. 2004;10(8):957-967. (Pubitemid 39232748)
20. Galandiuk S, Sterioff S. The problems of organ donor shortage [editorial]. Mayo Clin Proc. 2005;80(3):320-321. (Pubitemid 40316292)
21. Freeman RB Jr, Wiesner RH, Harper A, et al; UNOS/OPTN Liver Disease Severity Score, UNOS/OPTN Liver and Intestine, and UNOS/OPTN Pediatric Transplantation Committees The new liver allocation system: moving toward evidence-based transplantation policy. Liver Transpl. 2002;8(9):851-858.
22. Schlitt HJ, Obed A. Should liver transplantation be excluded in elderly patients? Nat Clin Pract Gastroenterol Hepatol. 2008 May;5(5):242-243. Epub 2008 Mar 11. (Pubitemid 351637907)