Mangifera indica L. extract attenuates glutamate-induced neurotoxicity on rat cortical neurons

NeuroToxicology

Volumn 30, Issue 6, 2009, Pages 1053-1058

  Lemus Molina, Yeny ^a   Sánchez Gómez, Maria Victoria ^b   Delgado Hernández, René ^a   Matute, Carlos ^b  

^a Centro de Quimica Farmaceutica   (Cuba)

^b CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED SOBRE ENFERMEDADES NEURODEGENERATIVAS CIBERNED   (Spain)

Author keywords

Excitotoxicity; Mangifera indica; Mangiferin; Mitochondria; Reactive oxygen species

Indexed keywords

DICHLORODIHYDROFLUORESCEIN DIACETATE; GLUTAMIC ACID; MANGIFERA INDICA EXTRACT; MANGIFERIN; REACTIVE OXYGEN METABOLITE; TETRAMETHYLRHODAMINE;

ANIMAL CELL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN CELL; BRAIN CORTEX; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; EXCITOTOXICITY; FLUOROMETRY; MANGO; MITOCHONDRIAL MEMBRANE POTENTIAL; NERVE CELL CULTURE; NERVE CELL NECROSIS; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

ANALYSIS OF VARIANCE; ANIMALS; CELLS, CULTURED; CEREBRAL CORTEX; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; EMBRYO, MAMMALIAN; GLUTAMIC ACID; INTRACELLULAR FLUID; MEMBRANE POTENTIAL, MITOCHONDRIAL; NEURONS; OXIDATIVE STRESS; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES;

MANGIFERA INDICA; RATTUS;

EID: 71249128716     PISSN: 0161813X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuro.2009.06.012     Document Type: Article

References (32)

1. Ankarcrona M., Dypbukt J.M., Bonfoco M., Zhivotovsky B., Orrenius S., Lipton S.A., et al. Glutamate-induced neuronal death: a succession of necrosis or apoptosis depending on mitochondrial function. Neuron 15 (1995) 961-973
2. Atlante A., Calissano P., Bobba A., Giannattasio S., Marra E., and Passarella S. Glutamate neurotoxicity, oxidative stress and mitochondria. FEBS Lett 497 (2001) 1-5
3. Bastianetto S., Yao Z.X., Papadopoulos V., and Quirion R. Neuroprotective effects of green and black teas and their catechin gallate esters against beta-amyloid-induced toxicity. Eur J Neurosci 23 1 (2006) 55-64
4. Bernardi P., Scorrano L., Colonna R., Petronilli V., and Di Lisa F. Mitochondria and cell death. Mechanistical aspects and methodological issues. Eur J Biochem 264 (1999) 687-701
5. Brewer G.J., Torricelli J.R., Evege E.K., and Price P.J. Optimized survival of hippocampal neurons in B27-supplemented Neurobasal, a new serum-free medium combination. J Neurosc Res 35 (1993) 567-576
6. Cheung N.S., Pascoe C.J., Giardina S.F., John C.A., and Beart P.M. Micromolar l-glutamate induces extensive apoptosis in an apoptotic-necrotic continuum of insult-dependent, excitotoxic injury in cultured cortical neurons. Neuropharmacol 37 (1998) 1419-1429
7. Campos-Esparza M.R., Sanchez-Gomez M.V., and Matute C. Molecular mechanisms of neuroprotection by two natural antioxidant polyphenols. Cell Calcium 45 (2009) 358-368
8. Cho J.Y., Kim I.S., Jang Y.H., Kim A.R., and Lee S.R. Protective effect of quercetin, a natural flavonoid against neuronal damage after transient global cerebral ischemia. Neurosci Lett 404 3 (2006) 330-335
9. Choi D.W. Calcium: still center-stage in hypoxic-ischemic neuronal death. Trends in Neurosci 18 (1995) 58-60
10. 2+ exchanger in hypoxic reoxygenated guinea pig ventricular myocytes. Am J Physiol-Heart Circulat Physiol 286 (2004) 955-963
11. García D., Leiro J., Delgado R., Sanmartin M.L., and Ubeira F.M. Mangifera indica L. extract (Vimang) and mangiferin modulate mouse humoral immune responses. Phytother Res 17 (2003) 1182-1187
12. Garrido G., González D., Delporte C., Backhouse N., Quintero G., and Núñez-Sellés A.J. Analgesic and anti-inflammatory effects of Mangifera indica L. extract (Vimang). Phytother Res 15 (2001) 18-21
13. ®) against mouse ear edemas and its inhibition of eicosanoid production in J774 murine macrophages. Phytomedicine 13 (2006) 412-418
14. Gilgun-Sherki Y., Melamed E., and Offen D. The role of oxidative stress in the pathogenesis of multiple sclerosis: the need for effective antioxidant therapy. J Neurol 251 (2004) 261-268
15. Gottlieb M., Leal-Campanario R., Campos-Esparza M.R., Sánchez-Gómez M.V., Alberdi E., Arranz A., et al. Neuroprotection by two polyphenols following excitotoxicity and experimental ischemia. Neurobiol Dis 23 2 (2006) 374-386
16. Guo S., Bezard E., and Zhao B. Protective effect of green tea polphenols on the SH-SY5Y cells against 6-OHDA induced apoptosis through ROS-NO pathway. Free Rad Biol Med 39 (2005) 682-695
17. Ibarretxe G., Sánchez-Gómez M.V., Campos-Esparza M.R., Alberdi E., and Matute C. Differential oxidative stress in oligodendrocytes and neurons after excitotoxic insults and protection by natural polyphenols. Glia 52 (2006) 201-211
18. 2+ and neurodegenerative disease. Eur J Pharmacol 447 (2002) 177-188
19. Martínez G., Delgado R., Perez G., Garrido G., Núñez-Sellés A.J., and León O.S. Evaluations of the in vitro antioxidant activity of Mangifera indica L. extract (EMi). Phytotherapy Res 14 (2000) 424-427
20. Martínez-Sánchez G., Candelario-Jalil E., Giuliani A., León O.S., Sam S., Delgado R., et al. Mangifera indica L. extract (EMi) reduces ischaemia-induced neuronal loss and oxidative damage in the gerbil brain. Free Radic Res 35 5 (2001) 465-473
21. Mattson M.P., Pedersen W.A., Duan W., Culmsee C., and Camandola S. Cellular and molecular mechanism underlying perturbed energy metabolism and neuronal degeneration in Alzheimer's and Parkinson's diseases. Ann N Y Acad Sci 893 (1999) 154-175
22. Matute C., Alberdi E., Ibarretxe G., and Sánchez-Gómez M.V. Excitotoxicity in glial cells. Eur J Pharmacol 447 (2002) 239-246
23. Michaelis M.L. Drugs targeting Alzheimer's disease: some things old and some things new. J Pharmacol Experim Ther 304 (2003) 897-904
24. Michaels R.L., and Rothman S.M. Glutamate neurotoxicity in vitro: antagonist pharmacology and intracellular calcium concentrations. J Neurosci 10 (1990) 283-292
25. Núñez-Sellés A., Vélez-Castro H., Agüero-Agüero J., González-González J., Naddeo F., and De Simone F. Isolation and quantitative analysis of phenolic antioxidants, free sugars, fatty acids and polyols from mango (Mangifera indica L.) stem bark aqueous decoction used in Cuba as nutritional supplement. J Agricult Food Chem 50 (2002) 762-766
26. 2+-citrate. Eur J Pharmacol 513 (2005) 47-55
27. Rice-Evans C. Flavonoid antioxidants. Curr MedChem 8 (2001) 797-807
28. Reynolds I.J., and Hastings T.G. Glutamate induces the production of reactive oxygen species in cultured forebrain neurons following NMDA receptor activation. J Neurosci 15 (1995) 3318-3327
29. Roden M.M., Lee K.H., Panelli M.C., and Marincola F.M. A novel cytolysis assay using fluorescent labelling and quantitative fluorescent scanning technology. J Immunol Methods 226 (1999) 29-41
30. Sánchez-Gómez M.V., Alberdi E., Ibarretxe G., Torre I., and Matute C. Caspase-dependent and caspase-independent oligodendrocyte death mediated by AMPA and kainate receptors. J Neurosci 23 (2003) 9519-9528
31. i during metabolic inhibition. J Mol Cell Cardiol 35 (2003) 331-336
32. Ward M.W., Rego A.C., Frenguelli B.G., and Nicholls D.G. Mitochondrial membrane potential and glutamate excitotoxicity in cultured cerebellar granule cells. J Neurosci 20 (2000) 7208-7219