Summary of contributions to GAW group 15: Family-based samples are useful in identifying common polymorphisms associated with complex traits

Genetic Epidemiology

Volumn 33, Issue SUPPL. 1, 2009, Pages

  Knight, Stacey ^a   Uh, Hae Won ^b   Martinez, Maria ^c,d  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c INSERM   (France)

^d UNIVERSITÉ DE TOULOUSE   (France)

Author keywords

Association; Linkage; Parent of origin effect

Indexed keywords

CONFERENCE PAPER; CONTROLLED STUDY; FAMILY; GENETIC ANALYSIS; GENETIC LINKAGE; GENETIC POLYMORPHISM; GENETIC TRAIT; GENETIC VARIABILITY; GENOTYPE; HERITABILITY; HUMAN; HYPERTENSION; INHERITANCE; LINKAGE ANALYSIS; PEDIGREE ANALYSIS; PENETRANCE; PHENOTYPE; POPULATION GENETICS; QUANTITATIVE TRAIT; SINGLE NUCLEOTIDE POLYMORPHISM;

CARDIOVASCULAR DISEASES; EPISTASIS, GENETIC; FEMALE; GENOME-WIDE ASSOCIATION STUDY; GENOMIC IMPRINTING; HUMANS; LINKAGE (GENETICS); MALE; MODELS, GENETIC; MOLECULAR EPIDEMIOLOGY; PEDIGREE; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 71249111472     PISSN: 07410395     EISSN: 10982272     Source Type: Journal    
DOI: 10.1002/gepi.20480     Document Type: Conference Paper

References (22)

1. Abecasis GR, Cardon LR, Cookson WO. 2000. A general test of association for quantitative traits in nuclear families. Am J Hum Genet 66:279-292.
2. Antoniou AC, Easton DF. 2003. Polygenic inheritance of breast cancer: implications for design of association studies. Genet Epidemiol 25:190-202. (Pubitemid 37296594)
3. Baron M. 2001. The search for complex disease genes: fault by linkage or fault by association? Mol Psychiatry 6:143-149.
4. Boerwinkle E, Chakraborty R, Sing CF. 1986. The use of measured genotype information in the analysis of quantitative phenotypes in man. I. Models and analyticalmethods. Ann Hum Genet 50:181-194. (Pubitemid 16116788)
5. Browning SR, Briley JD, Briley LP, Chandra G, Charnecki JH, Ehm MG, Johansson KA, Jones BJ, Karter AJ, Yarnall DP, Wagner MJ. 2005. Case-control single-marker and haplotypic association analysis of pedigree data. Genet Epidemiol 28:110-122.
6. Cupples LA, Heard-Costa N, Lee M, Atwood LD, for the Framingham Heart Study Investigators. 2009. Genetic Analysis Workshop 16 Problem 2: Framingham Heart Study data. BMC Proc 3:S2.
7. Haseman JK, Elston RC. 1972. The investigation of linkage between a quantitative trait and a marker locus. Behav Genet 2:3-19.
8. Havill LM, Dyer TD, Richardson DK, Mahaney MC, Blangero J. 2005. The quantitative trait linkage disequilibrium test: a more powerful alternative to the quantitative transmission disequilibrium test for use in the absence of population stratification. BMC Genet 6:S91. (Pubitemid 46443059)
9. Huang C, Li K, Saint Fleur R, Chang S-W, Choi SH, Shen T, Shin SY, Finch SJ, Mendell NR. 2009. Family-based analysis of a myocardial infarction endophenotype: comparison of sampling designs. BMC Proc 3:S120.
10. Kathiresan S,Willer CJ, Peloso GM, Demissie S, Musunuru K, Schadt EE, Kaplan L, Bennett D, Li Y, Tanaka T, Voight BF, Bonnycastle LL, Jackson AU, Crawford G, Surti A, Guiducci C, Burtt NP, Parish S, Clarke R, Zelenika D, Kubalanza KA, Morken MA, Scott LJ, Stringham HM, Galan P, Swift AJ, Kuusisto J, Bergman RN, Sundvall J, Laakso M, Ferrucci L, Scheet P, Sanna S, Uda M, Yang Q, Lunetta KL, Dupuis J, de Bakker PI, O'Donnell CJ, Chambers JC, Kooner JS, Hercberg S, Meneton P, Lakatta EG, Scuteri A, Schlessinger D, Tuomilehto J, Collins FS, Groop L, Altshuler D, Collins R, Lathrop GM, Melander O, Salomaa V, Peltonen L, Orho-Melander M, Ordovas JM, Boehnke M, Abecasis GR, Mohlke KL, Cupples LA. 2009. Common variants at 30 loci contribute to polygenic dyslipidemia. Nat Genet 41:56-65.
11. Kent WJ, Sugnet CW, Furey TS, Roskin KM, Pringle TH, Zahler AM, Haussler D. 2002. The human genome browser at UCSC. Genome Res 12:996-1006.
12. Knight S, Abo RP, Wong J, Thomas A, Camp NJ. 2009. Pedigree association: assigning individual weights to pedigree members for genetic association analysis. BMC Proc 3:S121.
13. Kraja AT, Culverhouse R, Daw EW, Wu J, Van Brunt A, Province MA, Borecki IB. 2009. The Genetic Analysis Workshop 16 Problem 3: simulation of heritable longitudinal cardiovascular phenotypes based on actual genome-wide single-nucleotide polymorphisms in the Framingham Heart Study. BMC Proc 3:S4.
14. McArdle PF, O'Connell JR, Pollin TI, Baumgarten M, Shuldiner AR, Peyser PA, Mitchell BD. 2007. Accounting for relatedness in family based genetic association studies. Hum Hered 64:234-242. (Pubitemid 47036986)
15. Saint Pierre A, Vitezica Z, Martinez M. 2009. A comparative study of three methods for detecting association of quantitative traits in samples of related subjects. BMC Proc 3:S122.
16. Sasieni PD. 1997. From genotypes to genes: doubling the sample size. Biometrics 53:1253-1261.
17. Thornton T, McPeek MS. 2007. Case-control association testing with related individuals: a more powerful quasi-likelihood score test. Am J Hum Genet 81:321-337. (Pubitemid 47236079)
18. Uh H-W, van der Wijk HJ, Houwing-Duistermaat JJ. 2009. Testing for genetic association taking into account phenotypic information of relatives. BMC Proc 3:S123.
19. Weinberg CR. 1999. Methods for detection of parent-of-origin effects in genetic studies of case-parents triads. Am J Hum Genet 65:229-235.
20. Weinberg CR, Wilcox AJ, Lie RT. 1998. A log-linear approach to case-parent-triad data: assessing effects of disease genes that act either directly or through maternal effects and that may be subject to parental imprinting. Am J Hum Genet 62:969-978.
21. Wilcox AJ, Weinberg CR, Lie RT. 1998. Distinguishing the effects of maternal and offspring genes through studies of "case-parent triads". Am J Epidemiol 148:893-901.
22. Yang J, Lin S. 2009. Detection of imprinting and heterogeneous maternal effects on high blood pressure using Framingham Heart Study data. BMC Proc 3:S125.