Co-engagement of α4β1 integrin (VLA-4) and CD4 or CD8 is necessary to induce maximal Erk1/2 phosphorylation and cytokine production in human T cells

Human Immunology

Volumn 71, Issue 1, 2010, Pages 23-28

  Kim, Tae Kon ^a,c   Billard, Matthew J ^b,d   Wieder, Eric D ^a   McIntyre, Bradley W ^b,c   Komanduri, Krishna V ^a,c  

^a UNIVERSITY OF MIAMI   (United States)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^c UNIVERSITY OF TEXAS   (United States)

^d DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

CD4; CD8; Co stimulation; Human; Integrin; T lymphocyte

Indexed keywords

CD28 ANTIGEN; CD3 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 2; MITOGEN ACTIVATED PROTEIN KINASE 1; VERY LATE ACTIVATION ANTIGEN 4;

ANTIGEN BINDING; ANTIGEN FUNCTION; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME PHOSPHORYLATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION;

ANTIGENS, CD28; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CYTOKINES; ENZYME ACTIVATION; HUMANS; INTEGRIN ALPHA4BETA1; LYMPHOCYTE ACTIVATION; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PHOSPHORYLATION; RECEPTORS, ANTIGEN, T-CELL;

EID: 71249109305     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humimm.2009.09.360     Document Type: Article

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